Publications by authors named "Howard Donninger"

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RALGEF inhibitors suppress RAS-driven pancreatic cancer and metastasis.
Howard Donninger, Rachel Ferrill, Becca von Baby, Katie R Hobbing, William L Dean

J Biol Chem· October 2025

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NORE1A loss promotes MASLD/MASH.
Howard Donninger, Katherine Hobbing, Gavin E Arteel, Geoffrey J Clark

Transgenic Res· October 2024

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Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy.
Omar S Sarkar, Howard Donninger, Numan Al Rayyan, Lewis C Chew, Bryce Stamp

Sci Adv· June 2023

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Detection of Endogenous RASSF1A Interacting Proteins.
Howard Donninger, Desmond Harrell-Stewart, Geoffrey J Clark

Methods Mol Biol· June 2021

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Cancer Vaccines: Promising Therapeutics or an Unattainable Dream.
Howard Donninger, Chi Li, John W Eaton, Kavitha Yaddanapudi

Vaccines (Basel)· June 2021

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Regulatory Role of Immune Cell-Derived Extracellular Vesicles in Cancer: The Message Is in the Envelope.
Chi Li, Howard Donninger, John Eaton, Kavitha Yaddanapudi

Front Immunol· April 2021

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Human polymorphonuclear neutrophils specifically recognize and kill cancerous cells.
Jun Yan, Goetz Kloecker, Chris Fleming, Michael Bousamra, Richard Hansen, Howard Donninger

Oncoimmunology· February 2021

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The RASSF1A Tumor Suppressor Binds the RasGAP DAB2IP and Modulates RAS Activation in Lung Cancer.
Desmond R Harrell Stewart, M Lee Schmidt, Howard Donninger, Geoffrey J Clark

Cancers (Basel)· December 2020

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Simultaneous Quantification of Nucleosides and Nucleotides from Biological Samples.
Liqing He, Xiaoli Wei, Xipeng Ma, Xinmin Yin, Ming Song, Howard Donninger

J Am Soc Mass Spectrom· June 2019

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The role of RASSF proteins in modulating RAS driven lung tumors .
Desmond Harrell Stewart, Katherine Hobbing, M Lee Schmidt, Howard Donninger, Geoffrey J Clark

J Thorac Dis· May 2019

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RASSF1A Deficiency Enhances RAS-Driven Lung Tumorigenesis.
M Lee Schmidt, Katharine R Hobbing, Howard Donninger, Geoffrey J Clark

Cancer Res· May 2018

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The role of the NORE1A tumor suppressor in Oncogene-Induced Senescence.
Thibaut Barnoud, M Lee Schmidt, Howard Donninger, Geoffrey J Clark

Cancer Lett· August 2017

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Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.
Payal Arora, Amartya Basu, M Lee Schmidt, Geoffrey J Clark, Howard Donninger

Hepatology· May 2017

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Ras signaling through RASSF proteins.
Howard Donninger, M Lee Schmidt, Jessica Mezzanotte, Thibaut Barnoud, Geoffrey J Clark

Semin Cell Dev Biol· October 2016

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NORE1A is a double barreled Ras senescence effector that activates p53 and Rb.
Howard Donninger, Thibaut Barnoud, Geoffrey J Clark

Cell Cycle· September 2016

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Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular Properties.
Michael T Scherzer, Sabine Waigel, Howard Donninger, Vennila Arumugam, Wolfgang Zacharias

PLoS One· May 2016

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Nore1a drives Ras to flick the P53 senescence switch.
Howard Donninger, Geoffrey J Clark

Mol Cell Oncol· May 2016

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Proteomics Analysis Reveals Novel RASSF2 Interaction Partners.
Thibaut Barnoud, Daniel W Wilkey, Michael L Merchant, Jennifer A Clark, Howard Donninger

Cancers (Basel)· March 2016

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Ras Regulates Rb via NORE1A.
Thibaut Barnoud, Howard Donninger, Geoffrey J Clark

J Biol Chem· February 2016

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A porcine model system of BRCA1 driven breast cancer.
Howard Donninger, Katharine Hobbing, M L Schmidt, Eric Walters, Laurie Rund

Front Genet· September 2015

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NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2.
Howard Donninger, Diego F Calvisi, Thibaut Barnoud, Jennifer Clark, M Lee Schmidt

J Cell Biol· March 2015

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The RASSF1A tumor suppressor regulates XPA-mediated DNA repair.
Howard Donninger, Jennifer Clark, Francesca Rinaldo, Nicholas Nelson, Thibaut Barnoud

Mol Cell Biol· January 2015

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Ras regulates SCF(β-TrCP) protein activity and specificity via its effector protein NORE1A.
M Lee Schmidt, Howard Donninger, Geoffrey J Clark

J Biol Chem· November 2014

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Cell cycle restriction is more important than apoptosis induction for RASSF1A protein tumor suppression.
Howard Donninger, Jennifer A Clark, Megan K Monaghan, M Lee Schmidt, Michele Vos

J Biol Chem· November 2014

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p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
Nina Holderness Parker, Howard Donninger, Michael J Birrer, Virna D Leaner

PLoS One· January 2014

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