Publications by authors named "Howard Fearnhead"

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In vitro co-culture of newly excysted juveniles (NEJs) with 3D HepG2 spheroids permits novel investigation of host-parasite interactions.
Aiste Vitkauskaite, Emma McDermott, Richard Lalor, Carolina De Marco Verissimo, Mahshid H Dehkordi, Howard Oliver Fearnhead

Virulence· December 2025

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Functionalizing Injectable Hydrogels with Cobalt-Based Metallacarboranes for Targeted Delivery in Triple-Negative Breast Cancer.
Neville Murphy, Roberto González-Gómez, Nivethitha Ashok, Enda O'Connell, Howard Fearnhead

Chembiochem· November 2025

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Correction to "Computational Characterization of the Interaction of CARD Domains in the Apoptosome".
Rita Ortega-Vallbona, Linda Johansson, Laureano E Carpio, Eva Serrano-Candelas, Sayyed Jalil Mahdizadeh, Howard Fearnhead

Biochemistry· October 2025

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Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay.
Roman Lambert, Eva Serrano Candelas, Pablo Aparicio, Aisling Murphy, Rafael Gozalbes, Howard Oliver Fearnhead

PLoS One· May 2025

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Computational Characterization of the Interaction of CARD Domains in the Apoptosome.
Rita Ortega-Vallbona, Linda Johansson, Laureano E Carpio, Eva Serrano-Candelas, Sayyed Jalil Mahdizadeh, Howard Fearnhead

Biochemistry· January 2025

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An atlas of caspase cleavage events in differentiating muscle cells.
Erik Gomez-Cardona, Mahshid H Dehkordi, Kolden Van Baar, Aiste Vitkauskaite, Olivier Julien, Howard O Fearnhead

Protein Sci· September 2024

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WITHDRAWN: Mera: A scalable high throughput automated micro-physiological system.
Finola E Cliffe, Conor Madden, Patrick Costello, Shane Devitt, Sumir Ramesh Mukkunda, Howard O Fearnhead

SLAS Discov· December 2023

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Mera: A scalable high throughput automated micro-physiological system.
Finola E Cliffe, Conor Madden, Patrick Costello, Shane Devitt, Sumir Ramesh Mukkunda, Howard O Fearnhead

SLAS Technol· August 2023

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Non-Canonical Roles of Apoptotic Caspases in the Nervous System.
Mahshid H Dehkordi, Robert G K Munn, Howard O Fearnhead

Front Cell Dev Biol· February 2022

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Apoptosome Formation through Disruption of the K192-D616 Salt Bridge in the Apaf-1 Closed Form.
Fatemeh Sahebazzamani, Saman Hosseinkhani, Leif A Eriksson, Howard O Fearnhead

ACS Omega· September 2021

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Non-lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins.
Eli Arama, Luis Alberto Baena-Lopez, Howard O Fearnhead

FEBS J· April 2021

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A robust platform for high-throughput screening of therapeutic strategies for acute and chronic spinal cord injury.
Vaibhav Patil, Enda O'Connell, Leo R Quinlan, Howard Fearnhead, Siobhan McMahon

iScience· March 2021

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Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Ali-Reza Noori, Amin Tashakor, Maryam Nikkhah, Leif A Eriksson, Saman Hosseinkhani, Howard O Fearnhead

Biochimie· January 2021

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Density Functional Theory (DFT)-Aided Structure Elucidation of Linear Diterpenes from the Irish Brown Seaweed .
Vangelis Smyrniotopoulos, Daria Firsova, Howard Fearnhead, Laura Grauso, Alfonso Mangoni

Mar Drugs· January 2021

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Oxygenated Acyclic Diterpenes with Anticancer Activity from the Irish Brown Seaweed .
Vangelis Smyrniotopoulos, Christian Merten, Daria Firsova, Howard Fearnhead, Deniz Tasdemir

Mar Drugs· November 2020

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Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts.
Mahshid H Dehkordi, Amin Tashakor, Enda O'Connell, Howard O Fearnhead

Cell Death Dis· May 2020

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The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
Elaheh Sadat Hosseini, Maryam Nikkhah, Amir Ali Hamidieh, Howard O Fearnhead, Jean-Paul Concordet

J Cell Sci· May 2020

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Droplet Combinations: A Scalable Microfluidic Platform for Biochemical Assays.
Finola E Cliffe, Mark Lyons, Daniel C Murphy, Lisa McInerney, Niall Hurley, Howard O Fearnhead

SLAS Technol· April 2020

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A Novel High-Throughput Screening Platform Identifies Itaconate Derivatives from Marine as Inhibitors of Mesenchymal Stem Cell Differentiation.
Pietro Marchese, Nipun Mahajan, Enda O'Connell, Howard Fearnhead, Maria Tuohy

Mar Drugs· April 2020

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A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Amin Tashakor, Mahshid H-Dehkordi, Enda O'Connell, Sergi Gomez Ganau, Rafael Gozalbes, Howard O Fearnhead

FEBS Open Bio· July 2019

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How do we fit ferroptosis in the family of regulated cell death?
Howard O Fearnhead, Peter Vandenabeele, Tom Vanden Berghe

Cell Death Differ· December 2017

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Viral hijacking of host caspases: an emerging category of pathogen-host interactions.
Patrick F Connolly, Howard O Fearnhead

Cell Death Differ· August 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Howard Fearnhead

Autophagy· October 2016

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DNA-PK activity is associated with caspase-dependent myogenic differentiation.
Patrick F Connolly, Howard O Fearnhead

FEBS J· October 2016

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Mesenchymal stem cells and a vitamin D receptor agonist additively suppress T helper 17 cells and the related inflammatory response in the kidney.
Michelle M Duffy, Bairbre A McNicholas, David A Monaghan, Shirley A Hanley, Jill M McMahon, Howard O Fearnhead

Am J Physiol Renal Physiol· December 2014

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