Publications by authors named "Howard Greenberg"

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Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults.
Jincheng Yang, Mina Nikanjam, Edmund V Capparelli, Shirley M Tsunoda, Howard E Greenberg

J Clin Pharmacol· November 2019

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Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach.
Jincheng Yang, Maulik Patel, Mina Nikanjam, Edmund V Capparelli, Shirley M Tsunoda, Howard E Greenberg

J Clin Pharmacol· September 2018

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A call to incorporate systems theory and human factors into the existing investigation of harm in clinical research involving healthcare products.
Brian D Edwards, Bernard Bégaud, Esther Daemen, Ioannis Dokas, Jonathan M Fishbein, Howard E Greenberg

Br J Clin Pharmacol· November 2017

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Hot Button Protocol and Operational Issues Between Sponsors and Sites in Clinical Pharmacology Studies: A Moderated Forum Session.
Gary L Steinman, William B Smith, Mary L Westrick, Howard E Greenberg

Ther Innov Regul Sci· May 2017

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Safety in FIH Trials: A Summary of the Symposium "Fatal Drug Trial in Phase 1: Understanding Risk, Subject Safety, Timelines, and Cost".
Howard E Greenberg, Mattheus Thijs van Iersel, Mary L Westrick, William B Smith

Ther Innov Regul Sci· May 2017

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Structured Risk Assessment for First-in-Human Studies.
Mattheus Thijs van Iersel, Howard E Greenberg, Mary L Westrick

Ther Innov Regul Sci· May 2017

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Comprehensive review of visual defects reported with topiramate.
Lisa Ford, Jeffrey L Goldberg, Fred Selan, Howard E Greenberg, Yingqi Shi

Clin Ophthalmol· May 2017

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Is uveitis associated with topiramate use? A cumulative review.
Jeffrey L Goldberg, Amy G Lau, Bo Fan, Lisa Ford, Howard E Greenberg

Clin Ophthalmol· August 2016

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A 46-Year-Old Asian Woman With Liver Mass.
Gloria J Morris, Anne M Covey, Michael D'Angelica, Daniel T Chang, Yun Yen, Howard Greenberg

Semin Oncol· October 2015

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Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin.
Jules I Schwartz, Bret J Musser, Wesley K Tanaka, William V Taggart, Anish Mehta, Howard E Greenberg

Clin Pharmacol Drug Dev· September 2015

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Limited sampling strategy of partial area under the concentration-time curves to estimate midazolam systemic clearance for cytochrome P450 3A phenotyping.
Joanna C Masters, Denise M Harano, Howard E Greenberg, Shirley M Tsunoda, In-Jin Jang

Ther Drug Monit· February 2015

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Detection and localization of bile duct leaks after cholecystectomy using Gd-EOB-DTPA-enhanced MR cholangiography: retrospective study of 16 patients.
Gregory E Ratcliffe, Iain D Kirkpatrick, V Anik Sahni, Howard M Greenberg, Blair Henderson

J Comput Assist Tomogr· September 2014

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Evaluation of partial area under the concentration time curve to estimate midazolam apparent oral clearance for cytochrome P450 3A phenotyping.
Wei Tai, Sheryl L Gong, Shirley M Tsunoda, Howard E Greenberg, J Christopher Gorski

Drug Metabol Drug Interact· August 2014

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Investigators' Experience With Expedited Safety Reports Prior to the FDA's Final IND Safety Reporting Rule.
Judith M Kramer, David Vock, Howard E Greenberg, Cheri Janning, Lynda Szczech

Ther Innov Regul Sci· July 2014

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MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans.
Behzad B Pavri, Howard E Greenberg, Walter K Kraft, Nicole Lazarus, Joseph J Lynch

Circ Arrhythm Electrophysiol· December 2012

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Blastomycosis presenting as multiple splenic abscesses: Case report and review of the literature.
Sami Al-Nassar, Tracy Macnair, Jeremy Lipschitz, Howard Greenberg, Elly Trepman

Can J Infect Dis Med Microbiol· July 2011

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Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and without aprepitant.
S Aubrey Stoch, Cynthia Gargano, Jack Valentine, Matthew P Braun, M Gail Murphy, Howard E Greenberg

Cancer Chemother Pharmacol· June 2011

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Safety and immunogenicity of a novel Staphylococcus aureus vaccine: results from the first study of the vaccine dose range in humans.
Clayton Harro, Robert Betts, Walter Orenstein, Eun-Jeong Kwak, Howard E Greenberg

Clin Vaccine Immunol· December 2010

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Diurnal variation of the human adipose transcriptome and the link to metabolic disease.
Andrey Loboda, Walter K Kraft, Bernard Fine, Jeffrey Joseph, Michael Nebozhyn, Howard E Greenberg

BMC Med Genomics· February 2009

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Minimal effects of ritonavir and efavirenz on the pharmacokinetics of raltegravir.
Marian Iwamoto, Larissa A Wenning, Amelia S Petry, Martine Laethem, Marina De Smet, Howard E Greenberg

Antimicrob Agents Chemother· December 2008

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The pharmacokinetics of taurolidine metabolites in healthy volunteers.
Li Gong, Howard E Greenberg, James L Perhach, Scott A Waldman, Walter K Kraft

J Clin Pharmacol· June 2007

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Effect of aprepitant on the pharmacokinetics of intravenous midazolam.
Anup K Majumdar, Kerri X Yan, Diana V Selverian, Suna Barlas, Marvin Constanzer, Howard E Greenberg

J Clin Pharmacol· June 2007

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American College of Clinical Pharmacology position statement on the use of microdosing in the drug development process.
Joseph S Bertino, Howard E Greenberg, Michael D Reed,

J Clin Pharmacol· April 2007

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Human pharmacokinetics and interconversion of enantiomers of MK-0767, a dual PPARalpha/gamma agonist.
Ronda K Rippley, Kerri X Yan, Natalie D Matthews, Howard E Greenberg, Gary A Herman

J Clin Pharmacol· March 2007

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Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects.
Arthur J Bergman, Joanne Burke, Patrick Larson, Amy O Johnson-Levonas, Larisa Reyderman, Howard E Greenberg

J Clin Pharmacol· March 2006

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