Publications by authors named "Howard Stern"

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Duvelisib, an oral dual PI3K-δ, γ inhibitor, shows clinical activity in indolent non-Hodgkin lymphoma in a phase 1 study.
Ian W Flinn, Manish Patel, Yasuhiro Oki, Steven Horwitz, Francine F Foss, Howard Stern

Am J Hematol· November 2018

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Duvelisib, an oral dual PI3K-δ,γ inhibitor, shows clinical and pharmacodynamic activity in chronic lymphocytic leukemia and small lymphocytic lymphoma in a phase 1 study.
Susan O'Brien, Manish Patel, Brad S Kahl, Steven M Horwitz, Francine M Foss, Howard M Stern

Am J Hematol· November 2018

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Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma.
Steven M Horwitz, Raphael Koch, Pierluigi Porcu, Yasuhiro Oki, Alison Moskowitz, Howard Stern

Blood· February 2018

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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.
Olivier De Henau, Matthew Rausch, David Winkler, Luis Felipe Campesato, Cailian Liu, Howard Stern

Nature· November 2016

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HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.
Brenda C O'Connell, Katie O'Callaghan, Bonnie Tillotson, Mark Douglas, Nafeeza Hafeez, Howard Stern

PLoS One· August 2015

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Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass.
Mark J Solloway, Azadeh Madjidi, Chunyan Gu, Jeff Eastham-Anderson, Holly J Clarke, Howard Stern

Cell Rep· July 2015

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PTEN Loss Is Associated with Worse Outcome in HER2-Amplified Breast Cancer Patients but Is Not Associated with Trastuzumab Resistance.
Howard M Stern, Humphrey Gardner, Tomasz Burzykowski, Wafaa Elatre, Carol O'Brien

Clin Cancer Res· May 2015

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Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.
Genee Y Lee, Peter M Haverty, Li Li, Noelyn M Kljavin, Richard Bourgon, Howard Stern

Cancer Res· June 2014

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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Jinfeng Liu, Mark McCleland, Eric W Stawiski, Florian Gnad, Oleg Mayba, Howard M Stern

Nat Commun· May 2014

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High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck.
David S Shames, Juliet Carbon, Kim Walter, Adrian M Jubb, Cleopatra Kozlowski, Howard Stern

PLoS One· August 2013

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Oncogenic ERBB3 mutations in human cancers.
Bijay S Jaiswal, Noelyn M Kljavin, Eric W Stawiski, Emily Chan, Chaitali Parikh, Howard M Stern

Cancer Cell· May 2013

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Immunohistochemistry and fluorescence in situ hybridization assessment of HER2 in clinical trials of adjuvant therapy for breast cancer (NCCTG N9831, BCIRG 006, and BCIRG 005).
Edith A Perez, Michael F Press, Amylou C Dueck, Robert B Jenkins, Chungyeul Kim, Howard M Stern

Breast Cancer Res Treat· February 2013

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Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.
Jinfeng Liu, William Lee, Zhaoshi Jiang, Zhongqiang Chen, Suchit Jhunjhunwala, Howard M Stern

Genome Res· December 2012

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Phase Ib study of drozitumab combined with first-line mFOLFOX6 plus bevacizumab in patients with metastatic colorectal cancer.
Caio M Rocha Lima, Soley Bayraktar, Aurea M Flores, Jessica MacIntyre, Alberto Montero, Howard Stern

Cancer Invest· December 2012

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Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.
Chaitali Parikh, Vasantharajan Janakiraman, Wen-I Wu, Catherine K Foo, Noelyn M Kljavin, Howard M Stern

Proc Natl Acad Sci U S A· November 2012

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.
Charles M Rudin, Steffen Durinck, Eric W Stawiski, John T Poirier, Zora Modrusan, Howard M Stern

Nat Genet· October 2012

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Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth.
Nicholas S Wilson, Annie Yang, Becky Yang, Suzana Couto, Howard Stern

Cancer Cell· July 2012

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Analysis of Fcγ receptor IIIa and IIa polymorphisms: lack of correlation with outcome in trastuzumab-treated breast cancer patients.
Sara A Hurvitz, David J Betting, Howard M Stern, Emmanuel Quinaux, Jeremy Stinson

Clin Cancer Res· June 2012

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DNA methylation profiling defines clinically relevant biological subsets of non-small cell lung cancer.
Kim Walter, Thomas Holcomb, Tom Januario, Pan Du, Marie Evangelista, Howard Stern

Clin Cancer Res· April 2012

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The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.
Zhaoshi Jiang, Suchit Jhunjhunwala, Jinfeng Liu, Peter M Haverty, Michael I Kennemer, Howard M Stern

Genome Res· April 2012

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Improving treatment of HER2-positive cancers: opportunities and challenges.
Howard M Stern

Sci Transl Med· March 2012

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Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1.
Ai-Luen Wu, Ganesh Kolumam, Scott Stawicki, Yongmei Chen, Jun Li, Howard Stern

Sci Transl Med· December 2011

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Randomized phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer.
Jean-Charles Soria, Zsuzsanna Márk, Petr Zatloukal, Barna Szima, István Albert, Howard Stern

J Clin Oncol· November 2011

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PPM1H is a p27 phosphatase implicated in trastuzumab resistance.
Si Tuen Lee-Hoeflich, Thinh Q Pham, Don Dowbenko, Xander Munroe, James Lee, Howard M Stern

Cancer Discov· September 2011

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miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer.
Susanna Stinson, Mark R Lackner, Alex T Adai, Nancy Yu, Hyo-Jin Kim, Howard M Stern

Sci Signal· August 2011

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