Publications by authors named "Howard T Mount"

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In utero exposure to protease inhibitor-based antiretroviral regimens delays growth and developmental milestones in mice.
Ambalika Sarkar, Kayode Balogun, Monica S Guzman Lenis, Sebastian Acosta, Howard T Mount

PLoS One· January 2021

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Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.
Chloë R McDonald, Lindsay S Cahill, Keith T Ho, Jimmy Yang, Hani Kim, Howard T Mount

PLoS Pathog· September 2015

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Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease.
Beverly M Francis, Jimao Yang, Byung Jun Song, Saurabh Gupta, Mary Maj, Howard T J Mount

J Alzheimers Dis· October 2014

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PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria.
Lena Serghides, Chloe R McDonald, Ziyue Lu, Miriam Friedel, Cheryl Cui, Howard T J Mount

PLoS Pathog· March 2014

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Unesterified docosahexaenoic acid is protective in neuroinflammation.
Sarah K Orr, Sara Palumbo, Francesca Bosetti, Howard T Mount, Jing X Kang

J Neurochem· November 2013

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Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2.
Amy Hye Won Jeon, Christopher Böhm, Fusheng Chen, Hairu Huo, Xueying Ruan, Howard T J Mount

J Biol Chem· May 2013

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Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease.
Beverly M Francis, Jimao Yang, Enid Hajderi, Mary E Brown, Bernadeta Michalski, Howard T J Mount

Neuropsychopharmacology· July 2012

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Object recognition memory and BDNF expression are reduced in young TgCRND8 mice.
Beverly M Francis, John Kim, Meredith E Barakat, Stephan Fraenkl, Yeni H Yücel, Howard T J Mount

Neurobiol Aging· March 2012

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Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.
Christiane B Knobbe, Timothy J Revett, Yu Bai, Vinca Chow, Amy Hye Won Jeon, Howard T Mount

J Proteome Res· October 2011

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The sedative but not the memory-blocking properties of ethanol are modulated by α5-subunit-containing γ-aminobutyric acid type A receptors.
Loren J Martin, Agnieszka A Zurek, Robert P Bonin, Gabriel H T Oh, John H Kim, Howard T J Mount

Behav Brain Res· March 2011

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Region-specific distribution of β-amyloid peptide and cytokine expression in TgCRND8 mice.
Keran Ma, Howard T J Mount, JoAnne McLaurin

Neurosci Lett· March 2011

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Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related gamma-secretase.
Nobuo Sanjo, Taiichi Katayama, Hiroshi Hasegawa, Haifeng Jin, Monika Duthie, Howard T J Mount

Neurosci Lett· October 2010

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Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease.
Alexandra Auffret, Vanessa Gautheron, Mariaelena Repici, Rudolf Kraftsik, Howard T J Mount

J Neurosci· August 2009

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Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.
Shiyong Peng, Diego J Garzon, Monica Marchese, William Klein, Stephen D Ginsberg, Howard T J Mount

J Neurosci· July 2009

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Brainstem concentrations of cholesterol are not influenced by genetic ablation of the low-density lipoprotein receptor.
Ameer Y Taha, Chuck T Chen, Zhen Liu, John H Kim, Howard T J Mount

Neurochem Res· February 2009

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The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations.
Chuck T Chen, David W L Ma, John H Kim, Howard T J Mount, Richard P Bazinet

J Lipid Res· January 2008

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The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.
Joel C Watts, Bettina Drisaldi, Vivian Ng, Jing Yang, Bob Strome, Howard T J Mount

EMBO J· September 2007

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Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.
JoAnne McLaurin, Meredith E Kierstead, Mary E Brown, Cheryl A Hawkes, Mark H L Lambermon, Howard T J Mount

Nat Med· July 2006

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Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.
Victor Y Cheng, Loren J Martin, Erin M Elliott, John H Kim, Howard T J Mount

J Neurosci· April 2006

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Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
Bettina Drisaldi, Janaky Coomaraswamy, Peter Mastrangelo, Bob Strome, Jing Yang, Howard T J Mount

J Biol Chem· December 2004

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Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease.
Satyabrata Kar, Stephen P M Slowikowski, David Westaway, Howard T J Mount

J Psychiatry Neurosci· November 2004

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Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Howard T J Mount, Jean-Claude Martel, Paul Fluit, Yingji Wu, Eleanor Gallo-Hendrikx

J Neurochem· March 2004

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Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.
Fusheng Chen, Anurag Tandon, Nobuo Sanjo, Yong-Jun Gu, Hiroshi Hasegawa, Howard T J Mount

J Biol Chem· May 2003

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APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes.
Yongjun Gu, Fusheng Chen, Nobuo Sanjo, Toshitaka Kawarai, Hiroshi Hasegawa, Howard T J Mount

J Biol Chem· February 2003

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Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype.
Richard Rozmahel, Howard T J Mount, Fusheng Chen, Van Nguyen, Jean Huang

Proc Natl Acad Sci U S A· October 2002

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