Publications by authors named "Howard W Chambers"

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In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators.
Mary Beth Dail, Edward Caldwell Meek, Howard Wayne Chambers, Janice Elaine Chambers

Drug Chem Toxicol· July 2019

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Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain.
Ronald B Pringle, Edward C Meek, Howard W Chambers, Janice E Chambers

Toxicol Sci· December 2018

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Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX.
Janice E Chambers, Howard W Chambers, Kristen E Funck, Edward C Meek, Ronald B Pringle

Chem Biol Interact· November 2016

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Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates.
Janice E Chambers, Edward C Meek, Howard W Chambers

Ann N Y Acad Sci· June 2016

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Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase.
Alper Coban, Russell L Carr, Howard W Chambers, Kenneth O Willeford, Janice E Chambers

Toxicol Lett· April 2016

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Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates.
Janice E Chambers, Edward C Meek, Joshua P Bennett, W Shane Bennett, Howard W Chambers

Toxicology· January 2016

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The effect of PON1 enhancers on reducing acetylcholinesterase inhibition following organophosphate anticholinesterase exposure in rats.
Edward C Meek, Howard W Chambers, Ronald B Pringle, Janice E Chambers

Toxicology· October 2015

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Species differences in paraoxonase mediated hydrolysis of several organophosphorus insecticide metabolites.
Russell L Carr, Mary Beth Dail, Howard W Chambers, Janice E Chambers

J Toxicol· March 2015

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Novel nucleophiles enhance the human serum paraoxonase 1 (PON1)-mediated detoxication of organophosphates.
Janice E Chambers, Howard W Chambers, Edward C Meek, Kristen E Funck, Manikanthan H Bhavaraju

Toxicol Sci· January 2015

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Paraoxonase 1 polymorphisms within a Mississippi USA population as possible biomarkers of enzyme activities associated with disease susceptibility.
Chiquita Y McDaniel, Mary Beth Dail, Robert W Wills, Howard W Chambers, Janice E Chambers

Biochem Genet· December 2014

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Human paraoxonase 1 hydrolysis of nanomolar chlorpyrifos-oxon concentrations is unaffected by phenotype or Q192R genotype.
R Hunter Coombes, Edward C Meek, Mary Beth Dail, Howard W Chambers, Janice E Chambers

Toxicol Lett· October 2014

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Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates.
Janice E Chambers, Howard W Chambers, Edward C Meek, Ronald B Pringle

Chem Biol Interact· March 2013

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Synthesis and in vitro and in vivo inhibition potencies of highly relevant nerve agent surrogates.
Edward C Meek, Howard W Chambers, Alper Coban, Kristen E Funck, Ronald B Pringle, Janice E Chambers

Toxicol Sci· April 2012

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Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South.
R Hunter Coombes, J Allen Crow, MaryBeth Dail, Howard W Chambers, Robert W Wills, Janice E Chambers

Pharmacogenet Genomics· December 2011

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Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners?
Kimberly A Davis, J Allen Crow, Howard W Chambers, Edward C Meek, Janice E Chambers

Environ Health Perspect· August 2009

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