Publications by authors named "Hubert Borell"

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Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Hubert Borell

Drug Metab Dispos· October 2020

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An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data.
Alexander D James, Hilmar Schiller, Cyrille Marvalin, Yi Jin, Hubert Borell

Pharmacol Res Perspect· June 2020

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Metabolism and Disposition of Siponimod, a Novel Selective S1P/S1P Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism.
Ulrike Glaenzel, Yi Jin, Robert Nufer, Wenkui Li, Kirsten Schroer, Hubert Borell

Drug Metab Dispos· July 2018

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In vitro studies and in silico predictions of fluconazole and CYP2C9 genetic polymorphism impact on siponimod metabolism and pharmacokinetics.
Yi Jin, Hubert Borell, Anne Gardin, Mike Ufer, Felix Huth

Eur J Clin Pharmacol· April 2018

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CYP4F enzymes are responsible for the elimination of fingolimod (FTY720), a novel treatment of relapsing multiple sclerosis.
Yi Jin, Markus Zollinger, Hubert Borell, Alfred Zimmerlin, Christopher J Patten

Drug Metab Dispos· February 2011

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