Publications by authors named "Huda Alkhalaf"

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Hemp Seed Oil Inhibits the Adipogenicity of the Differentiation-Induced Human Mesenchymal Stem Cells through Suppressing the Cannabinoid Type 1 (CB1).
Albatul S Almousa, Pandurangan Subash-Babu, Ibrahim O Alanazi, Ali A Alshatwi, Huda Alkhalaf

Molecules· March 2024

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Ionizing radiation normalizes the features of active breast cancer stromal fibroblasts and suppresses their paracrine pro-carcinogenic effects.
Abdelilah Aboussekhra, Noura N Alraouji, Falah H Al-Mohanna, Huda Al-Khalaf

Transl Oncol· November 2023

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Epidemiology of cancer in Saudi Arabia thru 2010-2019: a systematic review with constrained meta-analysis.
Wedad Saeed Alqahtani, Nawaf Abdulrahman Almufareh, Dalia Mostafa Domiaty, Gadah Albasher, Manal Abduallah Alduwish, Huda Alkhalaf

AIMS Public Health· September 2020

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AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1.
Manar M AlAhmari, Huda H Al-Khalaf, Falah H Al-Mohanna, Hazem Ghebeh, Abdelilah Aboussekhra

Oncogenesis· August 2020

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Interleukin-8 Dedifferentiates Primary Human Luminal Cells to Multipotent Stem Cells.
Huda H Al-Khalaf, Hazem Ghebeh, Salma M Wakil, Falah Al-Mohanna, Abdelilah Aboussekhra

Mol Cell Biol· April 2020

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AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma.
Huda H Al-Khalaf, Abdelilah Aboussekhra

Oncotarget· August 2019

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Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects.
Huda H Al-Khalaf, Bothaina Al-Harbi, Adher Al-Sayed, Maria Arafah, Asma Tulbah

Mol Cell Biol· January 2019

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Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts.
Huda H Al-Khalaf, Hazem Ghebeh, Rabia Inass, Abdelilah Aboussekhra

Mol Cell Biol· January 2019

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p16 Controls p53 Protein Expression Through miR-dependent Destabilization of MDM2.
Huda H Al-Khalaf, Abdelilah Aboussekhra

Mol Cancer Res· August 2018

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Obesity and p16 Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.
Huda H Al-Khalaf, Mrad Amir, Falah Al-Mohanna, Asma Tulbah, Adher Al-Sayed

Mol Cell Biol· September 2017

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p16 enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction.
Huda H Al-Khalaf, Shreeram C Nallar, Dhananjaya V Kalvakolanu, Abdelilah Aboussekhra

Mol Carcinog· July 2017

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p16 induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1.
Huda H Al-Khalaf, Abdelilah Aboussekhra

Mol Carcinog· March 2017

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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells.
Huda A Al-Howail, Hana A Hakami, Basem Al-Otaibi, Amer Al-Mazrou, Maha H Daghestani

BMC Cancer· July 2016

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PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition.
Abeer Al-Qasem, Huda A Al-Howail, Mashael Al-Swailem, Amer Al-Mazrou, Basem Al-Otaibi

Mol Carcinog· March 2016

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ATR controls the UV-related upregulation of the CDKN1A mRNA in a Cdk1/HuR-dependent manner.
Huda H Al-Khalaf, Abdelilah Aboussekhra

Mol Carcinog· December 2014

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The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1.
Siti-Fauziah Hendrayani, Huda H Al-Khalaf, Abdelilah Aboussekhra

J Biol Chem· November 2014

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MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor ZEB1 and the protein kinase AKT.
Huda H Al-Khalaf, Abdelilah Aboussekhra

J Biol Chem· November 2014

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p16(INK4A) positively regulates p21(WAF1) expression by suppressing AUF1-dependent mRNA decay.
Huda H Al-Khalaf, Abdelilah Aboussekhra

PLoS One· March 2014

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The cyclin-dependent kinase inhibitor p16INK4a physically interacts with transcription factor Sp1 and cyclin-dependent kinase 4 to transactivate microRNA-141 and microRNA-146b-5p spontaneously and in response to ultraviolet light-induced DNA damage.
Huda H Al-Khalaf, Peer Mohideen, Shreeram C Nallar, Dhananjaya V Kalvakolanu, Abdelilah Aboussekhra

J Biol Chem· December 2013

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Survivin expression increases during aging and enhances the resistance of aged human fibroblasts to genotoxic stress.
Huda H Al-Khalaf, Abdelilah Aboussekhra

Age (Dordr)· June 2013

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Curcumin triggers p16-dependent senescence in active breast cancer-associated fibroblasts and suppresses their paracrine procarcinogenic effects.
Siti-Fauziah Hendrayani, Huda H Al-Khalaf, Abdelilah Aboussekhra

Neoplasia· June 2013

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ATR controls the p21(WAF1/Cip1) protein up-regulation and apoptosis in response to low UV fluences.
Huda H Al-Khalaf, Siti-Faujiah Hendrayani, Abdelilah Aboussekhra

Mol Carcinog· December 2012

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p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
Huda H Al-Khalaf, Dilek Colak, Maher Al-Saif, Albandary Al-Bakheet, Siti-Faujiah Hendrayani

PLoS One· December 2011

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The atr protein kinase controls UV-dependent upregulation of p16INK4A through inhibition of Skp2-related polyubiquitination/degradation.
Huda H Al-Khalaf, Siti-Faujiah Hendrayani, Abdelilah Aboussekhra

Mol Cancer Res· March 2011

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Expression of survivin and p16(INK4a)/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells.
Huda H Al-Khalaf, Boleslaw Lach, Ayman Allam, Maher Hassounah, Ahmed Alkhani

Brain Res· January 2008

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