Publications by authors named "Hugo Besedovsky"

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Evolution Has neither Goals nor Aims, Only Needs.
Hugo Besedovsky, Adriana Del Rey

Neuroimmunomodulation· November 2025

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A Glucocorticoid-Mediated Immunoregulatory Circuit Integrated at Brain Levels: Our Early Studies and a Present View.
Hugo Besedovsky, Adriana Del Rey

Neuroimmunomodulation· December 2024

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Combined Use of Intranasal Methylprednisolone and Allopregnanolone: Revisiting Anti-inflammatory and Remyelinating Treatment in a Murine Model of Multiple Sclerosis.
Iván Nicolás Pérez-Osorio, José Alejandro Espinosa-Cerón, Camila Álvarez-Gutiérrez, Rodrigo Gonzalez-Flores, Hugo Besedovsky

Front Biosci (Landmark Ed)· December 2024

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Sympathetic-Immune Interactions during Different Types of Immune Challenge.
Adriana Del Rey, Hugo Besedovsky

Neuroimmunomodulation· February 2024

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Intranasal Versus Intravenous Dexamethasone to Treat Hospitalized COVID-19 Patients: A Randomized Multicenter Clinical Trial.
Graciela Cárdenas, María Chávez-Canales, Ana María Espinosa, Antonio Jordán-Ríos, Daniel Anica Malagon, Hugo Besedovsky

Arch Med Res· February 2024

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The immune system tends to eliminate the host when it cannot control pathogenic threats: Evolutionary, medical, and epidemiologic perspectives.
Adriana Del Rey, Hugo Besedovsky

Brain Behav Immun· March 2023

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To protect or to kill: A persisting Darwinian immune dilemma.
Hugo O Besedovsky, Adriana Del Rey

Brain Behav Immun· July 2022

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Intranasal dexamethasone: a new clinical trial for the control of inflammation and neuroinflammation in COVID-19 patients.
Graciela Cárdenas, María Chávez-Canales, Ana María Espinosa, Antonio Jordán-Ríos, Daniel Anica Malagon, Hugo Besedovsky

Trials· February 2022

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Nose-to-Brain Delivery of Dexamethasone: Biodistribution Studies in Mice.
Iván Nicolás Pérez-Osorio, Alejandro Espinosa, Manuel Giraldo Velázquez, Patricia Padilla, Brandon Bárcena, Hugo Besedovsky

J Pharmacol Exp Ther· September 2021

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Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model.
Alejandro Espinosa, Gabriela Meneses, Anahí Chavarría, Raúl Mancilla, José Pedraza-Chaverri, Hugo Besedovsky

Neurotherapeutics· October 2020

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Intranasal Methylprednisolone Effectively Reduces Neuroinflammation in Mice With Experimental Autoimmune Encephalitis.
Dunia Rassy, Brandon Bárcena, Iván Nicolás Pérez-Osorio, Alejandro Espinosa, Alberto N Peón, Hugo O Besedovsky

J Neuropathol Exp Neurol· February 2020

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Glucocorticoids and sympathetic neurotransmitters modulate the acute immune response to Trypanosoma cruzi.
Eduardo Roggero, Adriana Del Rey, Johannes Wildmann, Hugo Besedovsky

Ann N Y Acad Sci· February 2019

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The immune system as a sensorial system that can modulate brain functions and reset homeostasis.
Hugo O Besedovsky

Ann N Y Acad Sci· February 2019

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Sepsis: developing new alternatives to reduce neuroinflammation and attenuate brain injury.
Gabriela Meneses, Graciela Cárdenas, Alejandro Espinosa, Dunia Rassy, Ivan Nicolás Pérez-Osorio, Hugo Besedovsky

Ann N Y Acad Sci· February 2019

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Treatment-Resistant Human Extraparenchymal Neurocysticercosis: An Immune-Inflammatory Approach to Cysticidal Treatment Outcome.
Asiel Arce-Sillas, Graciela Cárdenas, Diana Álvarez-Luquín, Marisela Hernandez, Adriana Del Rey, Hugo Besedovsky

Neuroimmunomodulation· January 2019

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Immune-Neuro-Endocrine Reflexes, Circuits, and Networks: Physiologic and Evolutionary Implications.
Adriana Del Rey, Hugo O Besedovsky

Front Horm Res· September 2017

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The clinical recovery of tuberculosis patients undergoing specific treatment is associated with changes in the immune and neuroendocrine responses.
Ariana Díaz, Bettina Bongiovanni, Luciano D'Attilio, Natalia Santucci, Griselda Dídoli, Hugo Besedovsky

Pathog Dis· September 2017

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The sympathetic nervous system affects the susceptibility and course of Trypanosoma cruzi infection.
Eduardo Roggero, Ana Rosa Pérez, Natalia Pollachini, Silvina Raquel Villar, Johannes Wildmann, Hugo Besedovsky

Brain Behav Immun· November 2016

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Mimicking disruption of brain-immune system-joint communication results in collagen type II-induced arthritis in non-susceptible PVG rats.
Christine Wolff, Rainer H Straub, Anja Hahnel, Anke Randolf, Johannes Wildmann, Hugo O Besedovsky

Mol Cell Endocrinol· November 2015

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Physiologic versus diabetogenic effects of interleukin-1: a question of weight.
Hugo O Besedovsky, Adriana Del Rey

Curr Pharm Des· April 2015

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Gender-associated differential expression of cytokines in specific areas of the brain during helminth infection.
Lorena López-Griego, Karen Elizabeth Nava-Castro, Valeria López-Salazar, Rosalía Hernández-Cervantes, Nelly Tiempos Guzmán, Hugo O Besedovsky

J Interferon Cytokine Res· February 2015

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Helminth infection alters mood and short-term memory as well as levels of neurotransmitters and cytokines in the mouse hippocampus.
Jorge Morales-Montor, Ofir Picazo, Hugo Besedovsky, Romel Hernández-Bello, Lorena López-Griego

Neuroimmunomodulation· October 2014

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A cytokine network involving brain-borne IL-1β, IL-1ra, IL-18, IL-6, and TNFα operates during long-term potentiation and learning.
Adriana del Rey, Detlef Balschun, Wolfram Wetzel, Anke Randolf, Hugo O Besedovsky

Brain Behav Immun· October 2013

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Adverse neuro-immune-endocrine interactions in patients with active tuberculosis.
Oscar Bottasso, María Luisa Bay, Hugo Besedovsky, Adriana Del Rey

Mol Cell Neurosci· March 2013

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Neuroimmunomodulation in health and disease.
Adriana del Rey, C Jane Welsh, Markus J Schwarz, Hugo O Besedovsky

Ann N Y Acad Sci· July 2012

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