Publications by authors named "Hugo Girard"

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Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes.
Hugo Girard, Olivier Potvin, Scott Nugent, Caroline Dallaire-Théroux, Stephen Cunnane

Neurobiol Aging· April 2018

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SRD5A polymorphisms and biochemical failure after radical prostatectomy.
Etienne Audet-Walsh, Judith Bellemare, Geneviève Nadeau, Louis Lacombe, Yves Fradet, Hugo Girard

Eur Urol· December 2011

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Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.
Judith Bellemare, Mélanie Rouleau, Hugo Girard, Mario Harvey, Chantal Guillemette

Drug Metab Dispos· October 2010

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Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation.
Eric Lévesque, Vincent Ménard, Isabelle Laverdière, Judith Bellemare, Olivier Barbier, Hugo Girard

Pharmacogenet Genomics· March 2010

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Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.
Vincent Ménard, Hugo Girard, Mario Harvey, Louis Pérusse, Chantal Guillemette

Hum Mutat· April 2009

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UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
Hugo Girard, Lesley M Butler, Lyne Villeneuve, Robert C Millikan, Rashmi Sinha

Mutat Res· September 2008

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Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity.
Hugo Girard, Eric Lévesque, Judith Bellemare, Kim Journault, Bertrand Caillier

Pharmacogenet Genomics· December 2007

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Regulation of the UGT1A1 bilirubin-conjugating pathway: role of a new splicing event at the UGT1A locus.
Eric Lévesque, Hugo Girard, Kim Journault, Johanie Lépine, Chantal Guillemette

Hepatology· January 2007

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The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
Hugo Girard, Lyne Villeneuve, Michael H Court, Louis-Charles Fortier, Patrick Caron

Drug Metab Dispos· July 2006

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UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver.
Hugo Girard, Jean Thibaudeau, Michael H Court, Louis-Charles Fortier, Lyne Villeneuve

Hepatology· August 2005

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Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.
Olivier Barbier, Hugo Girard, Yusuke Inoue, Hélène Duez, Lyne Villeneuve

Mol Pharmacol· January 2005

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Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.
Hugo Girard, Michael H Court, Olivier Bernard, Louis-Charles Fortier, Lyne Villeneuve

Pharmacogenetics· August 2004

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Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.
Lyne Villeneuve, Hugo Girard, Louis-Charles Fortier, Jean-Francois Gagné, Chantal Guillemette

J Pharmacol Exp Ther· October 2003

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