Publications by authors named "Hugo Wurtele"

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Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Yahya Benslimane, Thierry Bertomeu, Jasmin Coulombe-Huntington, Mary McQuaid, María Sánchez-Osuna, David Papadopoli, Daina Avizonis, Mariana De Sa Tavares Russo, Caroline Huard, Ivan Topisirovic

September 2020

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The lncRNA ELDR suppresses tumorigenicity of AML by interfering with DNA replication and chromatin accessibility.
Kaifee Arman, Julie Ross, Eva-Maria Piskor, Luca Lazzari, Virginie Calderon, Hugo Wurtele

Blood Adv· December 2025

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Focus on numbers - characterizing protein accumulation at DNA double-strand breaks.
Graziana Modica, Joannie Roy, Antoine G Godin, Hugo Wurtele, Santiago Costantino

J Cell Sci· June 2025

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R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity.
Florence Couteau, Laurence M Gagné, Karine Boulay, Philippe Rousseau, Mélissa Carbonneau, Hugo Wurtele

Nucleic Acids Res· June 2025

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Functional studies in yeast confirm the pathogenicity of a new GINS3 Meier-Gorlin syndrome variant.
Yosra Mehrjoo, Philippe M Campeau, Lama Al Abdi, Abdullah Aldowaish, Omar Abouyousef, Hugo Wurtele

Clin Genet· September 2024

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MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
Stefania Bottardi, Taylorjade Layne, Ailyn C Ramòn, Norreen Quansah, Hugo Wurtele

Front Immunol· April 2024

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SMARCAL1 ubiquitylation controls its association with RPA-coated ssDNA and promotes replication fork stability.
Maïlyn Yates, Isabelle Marois, Edlie St-Hilaire, Daryl A Ronato, Billel Djerir, Hugo Wurtele

PLoS Biol· March 2024

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Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins.
Roch Tremblay, Yosra Mehrjoo, Oumaima Ahmed, Antoine Simoneau, Mary E McQuaid, Hugo Wurtele

Mol Cell Biol· November 2023

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A Rapid and Efficient Method for the Extraction of Histone Proteins.
Charles Homsi, Roshan Elizabeth Rajan, Robin Minati, Edlie St-Hilaire, Eric Bonneil, Hugo Wurtele

J Proteome Res· August 2023

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A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21.
François Bélanger, Cassandra Roussel, Christina Sawchyn, Edlie St-Hilaire, Sari Gezzar-Dandashi, Hugo Wurtele

J Biol Chem· July 2023

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A genome-wide screen identifies SCAI as a modulator of the UV-induced replicative stress response.
Jean-François Lemay, Edlie St-Hilaire, Daryl A Ronato, Yuandi Gao, François Bélanger, Hugo Wurtele

PLoS Biol· October 2022

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Biallelic variant p.(Arg114Leu) causes Meier-Gorlin syndrome with craniosynostosis.
Maria J Nabais Sá, Kerry A Miller, Mary McQuaid, Nils Koelling, Andrew O M Wilkie, Hugo Wurtele

J Med Genet· August 2022

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Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.
Mary E McQuaid, Kashif Ahmed, Stephanie Tran, Justine Rousseau, Ranad Shaheen, Hugo Wurtele

JCI Insight· May 2022

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Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells.
Nicole L Batenburg, Sofiane Y Mersaoui, John R Walker, Yan Coulombe, Ian Hammond-Martel, Hugo Wurtele

Nucleic Acids Res· December 2021

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Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.
Maxime Uriarte, Nadine Sen Nkwe, Roch Tremblay, Oumaima Ahmed, Clémence Messmer, Hugo Wurtele

Nat Commun· November 2021

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Chromatin dynamics and DNA replication roadblocks.
Ian Hammond-Martel, Alain Verreault, Hugo Wurtele

DNA Repair (Amst)· August 2021

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TACIMA-218: A Novel Pro-Oxidant Agent Exhibiting Selective Antitumoral Activity.
Jamilah Abusarah, Yun Cui, Nehme El-Hachem, Abed El-Hakim El-Kadiry, Ian Hammond-Martel, Hugo Wurtele

Mol Cancer Ther· January 2021

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A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties.
Abed El-Hakim El-Kadiry, Jamilah Abusarah, Yun Emma Cui, Nehme El-Hachem, Ian Hammond-Martel, Hugo Wurtele

Front Pharmacol· March 2020

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A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase.
Nadine Sen Nkwe, Salima Daou, Maxime Uriarte, Jessica Gagnon, Nicholas Victor Iannantuono, Hugo Wurtele

J Cell Sci· February 2020

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Opto-magnetic capture of individual cells based on visual phenotypes.
Loïc Binan, François Bélanger, Maxime Uriarte, Jean François Lemay, Jean Christophe Pelletier De Koninck, Hugo Wurtele

Elife· April 2019

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An open-source algorithm for rapid unbiased determination of DNA fiber length.
Pierre Ghesquière, Abdelhamid Elsherbiny, Emile Fortier, Mary McQuaid, Javier Mazzaferri, Hugo Wurtele

DNA Repair (Amst)· February 2019

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Know your limits: RPA availability and chemoresistance in ovarian cancer.
Emile Fortier, Elliot Drobetsky, Hugo Wurtele

Oncotarget· January 2019

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Replication Protein A Availability during DNA Replication Stress Is a Major Determinant of Cisplatin Resistance in Ovarian Cancer Cells.
François Bélanger, Emile Fortier, Maxime Dubé, Jean-François Lemay, Rémi Buisson, Hugo Wurtele

Cancer Res· October 2018

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An interplay between multiple sirtuins promotes completion of DNA replication in cells with short telomeres.
Antoine Simoneau, Étienne Ricard, Hugo Wurtele

PLoS Genet· April 2018

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pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen .
Julien Chaillot, Faiza Tebbji, Carlos García, Hugo Wurtele, René Pelletier

Front Microbiol· October 2017

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