Publications by authors named "Hugues Beauchemin"

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Inhibiting the RNA helicase DDX3X in Burkitt lymphoma induces oxydative stress and impedes tumor progression in xenografts.
Hugues Beauchemin, Zeinab Dalloul, Eva-Maria Piskor, Virginie Calderon, Andrew Chatr-Aryamontri

Front Cell Dev Biol· July 2025

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The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma.
Marion Lacroix, Hugues Beauchemin, Cyrus Khandanpour, Tarik Möröy

Front Oncol· March 2023

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DDX3: a relevant therapeutic target for lymphoma?
Marion Lacroix, Hugues Beauchemin, Tarik Möröy

Expert Opin Ther Targets· December 2022

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The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis.
Marion Lacroix, Hugues Beauchemin, Jennifer Fraszczak, Julie Ross, Peiman Shooshtarizadeh

Cancer Res· September 2022

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Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice.
Hugues Beauchemin, Peiman Shooshtharizadeh, Jordan Pinder, Graham Dellaire, Tarik Möröy

Haematologica· October 2020

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Multifaceted Actions of GFI1 and GFI1B in Hematopoietic Stem Cell Self-Renewal and Lineage Commitment.
Hugues Beauchemin, Tarik Möröy

Front Genet· October 2020

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Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.
Peiman Shooshtarizadeh, Anne Helness, Charles Vadnais, Nelleke Brouwer, Hugues Beauchemin

Nat Commun· March 2019

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Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice.
Jennifer Fraszczak, Charles Vadnais, Marissa Rashkovan, Julie Ross, Hugues Beauchemin

Leukemia· January 2019

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The common, autoimmunity-predisposing 620Arg > Trp variant of PTPN22 modulates macrophage function and morphology.
Meihang Li, Hugues Beauchemin, Natalija Popovic, Alan Peterson, Eva d'Hennezel

J Autoimmun· May 2017

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controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes.
Hugues Beauchemin, Peiman Shooshtarizadeh, Charles Vadnais, Lothar Vassen, Yves D Pastore

Haematologica· March 2017

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Generation and characterization of human iPSC line MML-6838-Cl2 from mobilized peripheral blood derived megakaryoblasts.
Marten Hansen, Eszter Varga, Tatjana Wüst, Nelleke Brouwer, Hugues Beauchemin

Stem Cell Res· January 2017

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Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression.
Lothar Vassen, Hugues Beauchemin, Wafaa Lemsaddek, Joseph Krongold, Marie Trudel

PLoS One· June 2015

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Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice.
Mara Kornete, Hugues Beauchemin, Constantin Polychronakos, Ciriaco A Piccirillo

Autoimmunity· June 2013

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Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines.
Aabida Saferali, Elin Grundberg, Soizik Berlivet, Hugues Beauchemin, Lisanne Morcos

Epigenetics· January 2010

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Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch.
Hugues Beauchemin, Marie Trudel

Mol Cell Biol· March 2009

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BP1 is a negative modulator of definitive erythropoiesis.
Marthe-Sandrine Eiymo Mwa Mpollo, Mélissa Beaudoin, Patricia E Berg, Hugues Beauchemin, Vivette D'Agati

Nucleic Acids Res· December 2006

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Differential regulatory and compensatory responses in hematopoiesis/erythropoiesis in alpha- and beta-globin hemizygous mice.
Hugues Beauchemin, Marie-José Blouin, Marie Trudel

J Biol Chem· May 2004

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