Publications by authors named "Hugues De The"

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Retinoic acid disrupts an NPM1c/ROS/SENP3/ARF oncogenic axis in acute myeloid leukemia.
Rita Hleihel, Hala Skayneh, Hsin-Chieh Wu, Maguy Hamie, Abdallah Kurdi

Leukemia· November 2025

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Immune intervention is dispensable for retinoic acid/arsenic therapy of murine acute promyelocytic leukemia.
Cécile Esnault, Gael Fortin, Fang Qiu, Hassane Soilihi, Sylvie Souquère

Haematologica· September 2025

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[Pierre Tiollais (1934-2024), a pioneer in genetic engineering with a lifelong commitment to the hepatitis B virus].
Christian Bréchot, Patrick Charnay, Hugues de Thé, Anne Dejean, Marie-Louise Michel

Med Sci (Paris)· July 2025

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Conventional chemotherapy: millions of cures, unresolved therapeutic index.
Anthony Letai, Hugues de The

Nat Rev Cancer· March 2025

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Rnf111 has a pivotal role in regulating development of definitive hematopoietic stem and progenitor cells through the Smad2/3-Gcsfr/NO axis in zebrafish.
Xiaohui Liu, Jinghan Sha, Luxiang Wang, Zixuan Wang, Zhou Fang, Hugues De The

Haematologica· February 2025

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Tripartite RAR fusions explain RA resistance.
Hsin-Chieh Wu, Hugues de Thé

Blood· October 2024

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Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities.
Domitille Rérolle, Hsin-Chieh Wu, Hugues de Thé

Cold Spring Harb Perspect Med· September 2024

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Creg1 Regulates Erythroid Development via TGF-β/Smad2-Klf1 Axis in Zebrafish.
Xiao Han, Wenxin He, Dongguo Liang, Xiaohui Liu, Jun Zhou

Adv Sci (Weinh)· September 2024

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Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development.
Lin Yan, Shuiyi Tan, Haihong Wang, Hao Yuan, Xiaohui Liu

Leukemia· April 2024

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History of Developing Acute Promyelocytic Leukemia Treatment and Role of Promyelocytic Leukemia Bodies.
Pierre Bercier, Hugues de Thé

Cancers (Basel)· March 2024

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Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Pierre Bercier, Qian Qian Wang, Ning Zang, Jie Zhang, Chang Yang

Cancer Discov· December 2023

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Ypel5 regulates liver development and function in zebrafish.
Yun Deng, Xiao Han, Huiqiao Chen, Chaoxian Zhao, Yi Chen, Hugues de The

J Mol Cell Biol· August 2023

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The PML hub: An emerging actor of leukemia therapies.
Domitille Rérolle, Hugues de Thé

J Exp Med· August 2023

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Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival.
Rita Hleihel, Hala Skayneh, Hugues de Thé, Olivier Hermine, Ali Bazarbachi

Blood Cancer J· May 2023

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Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia.
Marie Sebert, Stéphanie Gachet, Thierry Leblanc, Alix Rousseau, Olivier Bluteau

Cell Stem Cell· February 2023

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Author Correction: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells.
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Pierre Therizols

Nat Commun· January 2023

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Zbtb14 regulates monocyte and macrophage development through inhibiting expression in zebrafish.
Yun Deng, Haihong Wang, Xiaohui Liu, Hao Yuan, Jin Xu

Elife· October 2022

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In APL, noncoding mutations and SNP converge on WT1.
Hsin-Chieh Wu, Hugues de Thé

Blood· September 2022

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Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells.
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Pierre Therizols

Nat Commun· September 2022

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Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.
Bryann Pardieu, Justine Pasanisi, Frank Ling, Reinaldo Dal Bello, Justine Penneroux

Leukemia· June 2022

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Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication.
Simona Moretti, Amal Kamal Abdel-Aziz, Elena Ceccacci, Isabella Pallavicini, Fabio Santoro

Leukemia· May 2022

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Sumoylation in Physiology, Pathology and Therapy.
Umut Sahin, Hugues de Thé, Valérie Lallemand-Breitenbach

Cells· February 2022

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Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.
Hsin-Chieh Wu, Domitille Rérolle, Caroline Berthier, Rita Hleihel, Takashi Sakamoto

Cancer Discov· December 2021

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Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML).
Hanane Djamai, Jeannig Berrou, Mélanie Dupont, Marie-Magdelaine Coudé, Marc Delord

Biomedicines· November 2021

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Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish.
Shuo Gao, Zixuan Wang, Luxiang Wang, Haihong Wang, Hao Yuan

PLoS Genet· August 2021

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