Publications by authors named "Hugues Gascan"

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Potential Patient-Reported Toxicities With Disulfiram Treatment in Late Disseminated Lyme Disease.
Alain Trautmann, Hugues Gascan, Raouf Ghozzi

Front Med (Lausanne)· April 2020

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Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis.
Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, Benjamin Lefevre, Muhammad Farooq, Hugues Gascan

Mediators Inflamm· March 2018

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Interleukin-27 and IFNγ regulate the expression of CXCL9, CXCL10, and CXCL11 in hepatitis.
Laëtitia Basset, Sylvie Chevalier, Yannic Danger, Muhammad Imran Arshad, Claire Piquet-Pellorce, Hugues Gascan

J Mol Med (Berl)· December 2015

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Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes.
Muhammad Imran Arshad, Pierre Guihard, Yannic Danger, Gregory Noel, Jacques Le Seyec, Hugues Gascan

Am J Physiol Gastrointest Liver Physiol· October 2015

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Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis.
Laurence Amiot, Nicolas Vu, Michel Rauch, Annie L'Helgoualc'h, Frédéric Chalmel, Hugues Gascan

J Hepatol· February 2014

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Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.
Florence Robert-Gangneux, Anne-Sophie Drogoul, Octavie Rostan, Claire Piquet-Pellorce, Jérome Cayon, Hugues Gascan

PLoS One· August 2012

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Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling.
Pierre Guihard, Yannic Danger, Bénédicte Brounais, Emmanuelle David, Régis Brion, Hugues Gascan

Stem Cells· April 2012

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IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants.
Francois Rousseau, Laetitia Basset, Josy Froger, Nathalie Dinguirard, Sylvie Chevalier, Hugues Gascan

Proc Natl Acad Sci U S A· November 2010

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Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.
Pierrick Marvie, Mariette Lisbonne, Annie L'helgoualc'h, Michel Rauch, Bruno Turlin, Hugues Gascan

J Cell Mol Med· June 2010

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Definition and characterization of an inhibitor for interleukin-31.
Emilie Venereau, Caroline Diveu, Linda Grimaud, Elisa Ravon, Josy Froger, Hugues Gascan

J Biol Chem· May 2010

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Molecular dissection of human interleukin-31-mediated signal transduction through site-directed mutagenesis.
Sabine Le Saux, François Rousseau, Fabien Barbier, Elisa Ravon, Linda Grimaud, Hugues Gascan

J Biol Chem· January 2010

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Prokineticin 1 induces CCL4, CXCL1 and CXCL8 in human monocytes but not in macrophages and dendritic cells.
Justin Monnier, Véronique Quillien, Claire Piquet-Pellorce, Claudine Leberre, Laurence Preisser, Hugues Gascan

Eur Cytokine Netw· December 2008

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Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain.
François Rousseau, Sylvie Chevalier, Catherine Guillet, Elisa Ravon, Caroline Diveu, Hugues Gascan

J Biol Chem· October 2008

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Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Jérôme Pène, Sylvie Chevalier, Laurence Preisser, Emilie Vénéreau, Marie-Hélène Guilleux, Hugues Gascan

J Immunol· June 2008

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Neonatal and adult microglia cross-present exogenous antigens.
Celine Beauvillain, Sabrina Donnou, Ulrich Jarry, Mari Scotet, Hugues Gascan

Glia· January 2008

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Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
Dorothée Duluc, Yves Delneste, Fang Tan, Marie-Pierre Moles, Linda Grimaud, Hugues Gascan

Blood· December 2007

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Neutrophils efficiently cross-prime naive T cells in vivo.
Céline Beauvillain, Yves Delneste, Mari Scotet, Audrey Peres, Hugues Gascan

Blood· October 2007

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Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation.
Katia Boniface, Caroline Diveu, Franck Morel, Nathalie Pedretti, Josy Froger, Hugues Gascan

J Immunol· April 2007

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The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps.
Sébastien Jaillon, Giuseppe Peri, Yves Delneste, Isabelle Frémaux, Andrea Doni, Hugues Gascan

J Exp Med· April 2007

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Molecular and functional characterization of a soluble form of oncostatin M/interleukin-31 shared receptor.
Caroline Diveu, Emilie Venereau, Josy Froger, Elisa Ravon, Linda Grimaud, Hugues Gascan

J Biol Chem· December 2006

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Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient.
François Rousseau, Jean-François Gauchat, James G McLeod, Sylvie Chevalier, Catherine Guillet, Hugues Gascan

Proc Natl Acad Sci U S A· June 2006

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Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling.
Matthias Stanke, Chi Vinh Duong, Manuela Pape, Markus Geissen, Guido Burbach, Hugues Gascan

Development· January 2006

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Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.
Gersende Caron, Dorothée Duluc, Isabelle Frémaux, Pascale Jeannin, Catherine David, Hugues Gascan

J Immunol· August 2005

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Reversal of some viral IL-6 electrostatic properties compared to IL-6 contributes to a loss of alpha receptor component recruitment.
David Perret, François Rousseau, Vinh Tran, Hugues Gascan

Proteins· July 2005

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Cardiotrophin-like cytokine labelling using Bir A biotin ligase: a sensitive tool to study receptor expression by immune and non-immune cells.
Isabelle Cognet, Florence Guilhot, Mélanie Gabriac, Sylvie Chevalier, Younes Chouikh, Hugues Gascan

J Immunol Methods· June 2005

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