Publications by authors named "Hugues Nury"

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Asynchronous subunit transitions prime acetylcholine receptor activation.
Mackenzie J Thompson, Christian J G Tessier, Anna Ananchenko, Camille Hénault, Johnathon R Emlaw, Hugues Nury

Science· October 2025

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Functional conformations or poor mimetics?
Hugues Nury, Rouslan G Efremov

Structure· May 2025

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Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT receptors.
Uriel López-Sánchez, Lachlan Jake Munro, Lucy Kate Ladefoged, Anders Juel Pedersen, Christian Colding Brun, Hugues Nury

Nat Struct Mol Biol· August 2024

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Author Correction: Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT receptors.
Uriel López-Sánchez, Lachlan Jake Munro, Lucy Kate Ladefoged, Anders Juel Pedersen, Christian Colding Brun, Hugues Nury

Nat Struct Mol Biol· July 2024

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Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Hugues Nury

Nat Commun· May 2024

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A release of local subunit conformational heterogeneity underlies gating in a muscle nicotinic acetylcholine receptor.
Mackenzie J Thompson, Farid Mansoub Bekarkhanechi, Anna Ananchenko, Hugues Nury, John E Baenziger

Nat Commun· February 2024

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Superiority of the Triple-Acting 5-HTR/5-HTR Antagonist and MAO-B Reversible Inhibitor over 5-HTR Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats.
Katarzyna Grychowska, Uriel López-Sánchez, Mathieu Vitalis, Geoffrey Canet, Grzegorz Satała, Hugues Nury

J Med Chem· November 2023

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Role of surfactants in electron cryo-microscopy film preparation.
Baptiste Michon, Uriel López-Sánchez, Jéril Degrouard, Hugues Nury, Amélie Leforestier

Biophys J· May 2023

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The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Hugues Nury

Nat Commun· August 2022

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Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor.
Eleftherios Zarkadas, Eva Pebay-Peyroula, Mackenzie John Thompson, Guy Schoehn, Tomasz Uchański, Hugues Nury

Neuron· April 2022

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Distinct classes of potassium channels fused to GPCRs as electrical signaling biosensors.
M Dolores García-Fernández, Franck C Chatelain, Hugues Nury, Anna Moroni, Christophe J Moreau

Cell Rep Methods· December 2021

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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.
Nicholas M Barnes, Gerard P Ahern, Carine Becamel, Joël Bockaert, Michael Camilleri, Hugues Nury

Pharmacol Rev· January 2021

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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Tomasz Uchański, Simonas Masiulis, Baptiste Fischer, Valentina Kalichuk, Uriel López-Sánchez, Hugues Nury

Nat Methods· January 2021

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The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor.
Eleftherios Zarkadas, Hong Zhang, Wensheng Cai, Gregory Effantin, Jonathan Perot, Hugues Nury

Structure· October 2020

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A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Camille M Hénault, Cedric Govaerts, Radovan Spurny, Marijke Brams, Argel Estrada-Mondragon, Hugues Nury

Nat Chem Biol· December 2019

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Conformational transitions of the serotonin 5-HT receptor.
Lucie Polovinkin, Ghérici Hassaine, Jonathan Perot, Emmanuelle Neumann, Anders A Jensen, Hugues Nury

Nature· November 2018

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Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor.
Ghérici Hassaïne, Cédric Deluz, Luigino Grasso, Romain Wyss, Ruud Hovius, Hugues Nury

Methods Mol Biol· April 2018

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X-ray structure of the mouse serotonin 5-HT3 receptor.
Ghérici Hassaine, Cédric Deluz, Luigino Grasso, Romain Wyss, Menno B Tol, Hugues Nury

Nature· August 2014

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Sedimentation velocity analytical ultracentrifugation in hydrogenated and deuterated solvents for the characterization of membrane proteins.
Aline Le Roy, Hugues Nury, Benjamin Wiseman, Jonathan Sarwan, Jean-Michel Jault

Methods Mol Biol· March 2014

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Large scale expression and purification of the mouse 5-HT3 receptor.
Ghérici Hassaine, Cédric Deluz, Menno B Tol, Xiao-Dan Li, Alexandra Graff, Hugues Nury

Biochim Biophys Acta· November 2013

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Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Radovan Spurny, Joachim Ramerstorfer, Kerry Price, Marijke Brams, Margot Ernst, Hugues Nury

Proc Natl Acad Sci U S A· October 2012

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A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Marie S Prevost, Ludovic Sauguet, Hugues Nury, Catherine Van Renterghem, Christèle Huon

Nat Struct Mol Biol· May 2012

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[X-ray structures of general anesthetics bound to their molecular targets].
Hugues Nury, Marc Delarue, Pierre-Jean Corringer

Med Sci (Paris)· December 2011

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X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Hugues Nury, Catherine Van Renterghem, Yun Weng, Alphonso Tran, Marc Baaden

Nature· January 2011

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Structural approaches of the mitochondrial carrier family.
Hugues Nury, Iulia Blesneac, Stephanie Ravaud, Eva Pebay-Peyroula

Methods Mol Biol· November 2010

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