Publications by authors named "Husain Attarwala"

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Immunostimulatory/Immunodynamic model of mRNA-1273 to guide pediatric vaccine dose selection.
Vijay Ivaturi, Husain Attarwala, Weiping Deng, Baoyu Ding, Sabine Schnyder Ghamloush

CPT Pharmacometrics Syst Pharmacol· January 2025

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Translational pharmacokinetic/pharmacodynamic model for mRNA-0184, an investigational therapeutic for the treatment of heart failure.
Neeraj Kaushal, Husain Attarwala, Mir Javid Iqbal, Rajnish Saini, Linh Van

Clin Transl Sci· August 2024

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Translational kinetic-pharmacodynamics of mRNA-6231, an investigational mRNA therapeutic encoding mutein interleukin-2.
Ivana Liric Rajlic, Beatriz Guglieri-Lopez, Nabeel Rangoonwala, Vijay Ivaturi, Linh Van, Husain Attarwala

CPT Pharmacometrics Syst Pharmacol· June 2024

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Translational Pharmacokinetic/Pharmacodynamic Model for mRNA-3927, an Investigational Therapeutic for the Treatment of Propionic Acidemia.
Husain Attarwala, Matthew Lumley, Min Liang, Vijay Ivaturi, Joe Senn

Nucleic Acid Ther· April 2023

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Mathematical Modeling and Experimental Validation of Extracellular Vesicle-Mediated Tumor Suppressor MicroRNA Delivery and Propagation in Ovarian Cancer Cells.
Srujan K Gandham, Husain Z Attarwala, Mansoor M Amiji

Mol Pharm· November 2022

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Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1.
Elisabeth Narayanan, Samantha Falcone, Sayda M Elbashir, Husain Attarwala, Kimberly Hassett

Antibodies (Basel)· October 2022

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Author Correction: A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus.
Allison August, Husain Z Attarwala, Sunny Himansu, Shiva Kalidindi, Sophia Lu

Nat Med· May 2022

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A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus.
Allison August, Husain Z Attarwala, Sunny Himansu, Shiva Kalidindi, Sophia Lu

Nat Med· December 2021

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Co-Silencing of Tissue Transglutaminase-2 and Interleukin-15 Genes in a Celiac Disease Mimetic Mouse Model Using a Nanoparticle-in-Microsphere Oral System.
Husain Z Attarwala, Kanika Suri, Mansoor M Amiji

Mol Pharm· August 2021

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Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects.
Bahru A Habtemariam, Verena Karsten, Husain Attarwala, Varun Goel, Megan Melch

Clin Pharmacol Ther· February 2021

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Pharmacokinetics and Biodistribution Analysis of Small Interference RNA for Silencing Tissue Transglutaminase-2 in Celiac Disease After Oral Administration in Mice Using Gelatin-Based Multicompartmental Delivery Systems.
Husain Z Attarwala, Kanika Suri, Mansoor M Amiji

Bioelectricity· June 2020

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Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure-Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin-Mediated (hATTR) Amyloidosis.
Xiaoping Zhang, Varun Goel, Husain Attarwala, Marianne T Sweetser, Valerie A Clausen

J Clin Pharmacol· January 2020

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Oral nucleic acid therapy using multicompartmental delivery systems.
Husain Attarwala, Murui Han, Jonghan Kim, Mansoor Amiji

Wiley Interdiscip Rev Nanomed Nanobiotechnol· March 2018

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Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.
Jayaprakash K Nair, Husain Attarwala, Alfica Sehgal, Qianfan Wang, Krishna Aluri

Nucleic Acids Res· November 2017

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Cosilencing Intestinal Transglutaminase-2 and Interleukin-15 Using Gelatin-Based Nanoparticles in an in Vitro Model of Celiac Disease.
Husain Attarwala, Valerie Clausen, Prasoon Chaturvedi, Mansoor M Amiji

Mol Pharm· September 2017

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An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Alfica Sehgal, Scott Barros, Lacramioara Ivanciu, Brian Cooley, June Qin, Husain Attarwala

Nat Med· May 2015

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Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract.
Christina Kriegel, Husain Attarwala, Mansoor Amiji

Adv Drug Deliv Rev· June 2013

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Multi-compartmental nanoparticles-in-emulsion formulation for macrophage-specific anti-inflammatory gene delivery.
Husain Attarwala, Mansoor Amiji

Pharm Res· June 2012

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Role of antibodies in cancer targeting.
Husain Attarwala

J Nat Sci Biol Med· July 2010

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