Publications by authors named "Hussein Aly"

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A novel synthetic bile acid derivative inhibits hepatitis B virus infection at entry step by interfering with the oligomerization of sodium taurocholate co-transporting polypeptide.
Gede Ngurah Rsi Suwardana, Takayuki Abe, Lin Deng, Chieko Matsui, Takashi Okitsu, Hussein H Aly

Antiviral Res· November 2025

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A synonymous mutation in the preS2 region enhances production of infectious hepatitis B virus.
Asako Murayama, Norie Yamada, Masaaki Toyama, Hussein Hassan Aly, Hironori Nishitsuji

Virology· November 2025

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RXR agonist S169 inhibits HBV/HDV entry in vitro by disrupting KIF4-dependent NTCP trafficking.
Sameh A Gad, Doaa A Abo Elwafa, Saied A Hussein, Kento Fukano, Takanobu Kato, Hussein H Aly

Antiviral Res· August 2025

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Advanced Hybrid Closed-Loop Insulin Delivery Is Associated With Improved Glycemic Indicators and Normalization of Small Nerve Fibre Structure in Adults With Type 1 Diabetes.
Hoda Gad, Einas Elgassim, Kawsar Mohamed Ayon Mohamud, Najlaa Sultan Al-Naimi, Hamad Ali Al-Sharshani, Hussein Ahmed Hussein Zaky Aly

J Peripher Nerv Syst· June 2025

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Exploring the tolerable region for HiBiT tag insertion in the hepatitis B virus genome.
Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Masaaki Toyama

mSphere· October 2024

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Antiviral effect of peptoids on hepatitis B virus infection in cell culture.
Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Natalia Molchanova

Antiviral Res· March 2024

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Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication.
Adi Ariffianto, Lin Deng, Takayuki Abe, Chieko Matsui, Masahiko Ito, Hussein Hassan Aly

J Virol· October 2023

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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes.
Hoda Gad, Einas Elgassim, Ibrahim Mohammed, Ahmad Yaser Alhaddad, Hussein Ahmed Hussein Zaky Aly

Diabetes Res Clin Pract· June 2023

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Longitudinal Studies of Wearables in Patients with Diabetes: Key Issues and Solutions.
Ahmad Yaser Alhaddad, Hussein Aly, Hoda Gad, Einas Elgassim, Ibrahim Mohammed

Sensors (Basel)· May 2023

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Recent Advances in Protective Vaccines against Hepatitis Viruses: A Narrative Review.
Ashraf Elbahrawy, Hassan Atalla, Mohamed Alboraie, Ahmed Alwassief, Ali Madian, Hussein H Aly

Viruses· January 2023

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Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen.
Ayaka Washizaki, Asako Murayama, Megumi Murata, Tomoko Kiyohara, Keigo Yato, Hussein Hassan Aly

Nat Commun· September 2022

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IFN-γ‒Induced APOBEC3B Contributes to Merkel Cell Polyomavirus Genome Mutagenesis in Merkel Cell Carcinoma.
Lusheng Que, Yingfang Li, Teruki Dainichi, Iwao Kukimoto, Tomoaki Nishiyama, Hussein H Aly

J Invest Dermatol· July 2022

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Sense and Learn: Recent Advances in Wearable Sensing and Machine Learning for Blood Glucose Monitoring and Trend-Detection.
Ahmad Yaser Alhaddad, Hussein Aly, Hoda Gad, Abdulaziz Al-Ali, Kishor Kumar Sadasivuni

Front Bioeng Biotechnol· May 2022

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Amino Acid Polymorphism in Hepatitis B Virus Associated With Functional Cure.
Takashi Honda, Norie Yamada, Asako Murayama, Masaaki Shiina, Hussein Hassan Aly

Cell Mol Gastroenterol Hepatol· March 2022

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The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro.
Sameh A Gad, Masaya Sugiyama, Masataka Tsuge, Kosho Wakae, Kento Fukano, Hussein H Aly

PLoS Pathog· March 2022

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Predicting COVID-19 cases using bidirectional LSTM on multivariate time series.
Ahmed Ben Said, Abdelkarim Erradi, Hussein Ahmed Aly, Abdelmonem Mohamed

Environ Sci Pollut Res Int· October 2021

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Current situation of viral hepatitis in Egypt.
Ashraf Elbahrawy, Marwa K Ibrahim, Ahmed Eliwa, Mohamed Alboraie, Ali Madian, Hussein Hassan Aly

Microbiol Immunol· September 2021

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Identification of natural compounds extracted from crude drugs as novel inhibitors of hepatitis C virus.
Xin Zheng, Rui Guo, Qingbo Liu, Kousho Wakae, Noriyuki Watanabe, Hussein H Aly

Biochem Biophys Res Commun· August 2021

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MafF Is an Antiviral Host Factor That Suppresses Transcription from Hepatitis B Virus Core Promoter.
Marwa K Ibrahim, Tawfeek H Abdelhafez, Junko S Takeuchi, Kosho Wakae, Masaya Sugiyama, Hussein H Aly

J Virol· July 2021

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N-Terminal PreS1 Sequence Regulates Efficient Infection of Cell-Culture-Generated Hepatitis B Virus.
Asako Murayama, Norie Yamada, Yoshiki Osaki, Masaaki Shiina, Hussein Hassan Aly

Hepatology· February 2021

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MCPIP1 reduces HBV-RNA by targeting its epsilon structure.
Yingfang Li, Lusheng Que, Kento Fukano, Miki Koura, Kouichi Kitamura, Hussein Hassan Aly

Sci Rep· November 2020

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Anti-viral effects of interferon-λ3 on hepatitis B virus infection in cell culture.
Norie Yamada, Asako Murayama, Masaaki Shiina, Hussein Hassan Aly, Masashi Iwamoto

Hepatol Res· March 2020

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Hepatitis B Virus Genotype-Dependent Vulnerability of Infected Cells to Immune Reaction in the Early Phase of Infection.
Masaaki Shiina, Norie Yamada, Ryuichi Sugiyama, Asako Murayama, Hussein Hassan Aly

Front Microbiol· October 2019

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Peroxiredoxin 1, a Novel HBx-Interacting Protein, Interacts with Exosome Component 5 and Negatively Regulates Hepatitis B Virus (HBV) Propagation through Degradation of HBV RNA.
Lin Deng, Xiang Gan, Masahiko Ito, Ming Chen, Hussein H Aly

J Virol· March 2019

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Evaluation of antiviral effects of novel NS5A inhibitors in hepatitis C virus cell culture system with full-genome infectious clones.
Asako Murayama, Kei Fujiwara, Norie Yamada, Masaaki Shiina, Hussein Hassan Aly

Antiviral Res· October 2018

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