Publications by authors named "Hyungshin Yim"

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TSG6 promotes epithelial-mesenchymal transition and tumor-associated macrophage polarization through Smad2/3 and MAPK signaling by facilitating TSG6-CD44-TGFβR1 or EGFR complex formation.
Hyun-Ji Oh, Ga-Hong Min, Da-Eun Kim, Sol-Bi Shin, Hyungshin Yim

Int J Biol Sci· August 2025

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Synergistic two-step inhibition approach using a combination of trametinib and onvansertib in KRAS and TP53-mutated colorectal adenocarcinoma.
Da-Eun Kim, Hyun-Ji Oh, Hyun-Jin Kim, Yeo-Bin Kim, Seung-Tae Kim, Hyungshin Yim

Biomed Pharmacother· January 2025

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Clinical applications of circulating biomarkers in non-small cell lung cancer.
Hyun-Ji Oh, Abdulhamid B Imam-Aliagan, Yeo-Bin Kim, Hyun-Jin Kim, Issac A Izaguirre, Hyungshin Yim

Front Cell Dev Biol· August 2024

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The Gene Induces Tumor Growth and Triggers Leptomeningeal Metastasis by Regulating the mTORC2 Signaling Pathway in Group 3 Medulloblastomas.
Elisabet Ampudia-Mesias, Charles S Cameron, Eunjae Yoo, Marcus Kelly, Sarah M Anderson, Hyungshin Yim

Int J Mol Sci· April 2024

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Targeting dysregulated lipid metabolism in the tumor microenvironment.
Do-Hee Kim, Na-Young Song, Hyungshin Yim

Arch Pharm Res· December 2023

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Invasive FoxM1 phosphorylated by PLK1 induces the polarization of tumor-associated macrophages to promote immune escape and metastasis, amplified by IFITM1.
Rong Xu, Young-Joo Lee, Chang-Hyeon Kim, Ga-Hong Min, Yeo-Bin Kim, Hyungshin Yim

J Exp Clin Cancer Res· November 2023

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Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21 signaling in acute kidney injury.
Da-Eun Kim, Hye Eun Byeon, Dae-Hoon Kim, Sang Geon Kim, Hyungshin Yim

Cell Biol Toxicol· August 2023

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PLK1-mediated phosphorylation of β-catenin enhances its stability and transcriptional activity for extracellular matrix remodeling in metastatic NSCLC.
Da-Eun Kim, Sol-Bi Shin, Chang-Hyeon Kim, Yeo-Bin Kim, Hyun-Ji Oh, Hyungshin Yim

Theranostics· February 2023

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Correction: PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma.
Hay-Ran Jang, Sol-Bi Shin, Chang-Hyeon Kim, Jae-Yeon Won, Rong Xu, Hyungshin Yim

Cell Death Differ· October 2022

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Improved anti-fibrotic effects by combined treatments of simvastatin and NS-398 in experimental liver fibrosis models.
Seong Hee Kang, Hyung Joon Yim, Ji-Won Hwang, Mi-Jung Kim, Young-Sun Lee, Hyungshin Yim

Korean J Intern Med· July 2022

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Mitotic protein kinase-driven crosstalk of machineries for mitosis and metastasis.
Chang-Hyeon Kim, Da-Eun Kim, Dae-Hoon Kim, Ga-Hong Min, Jung-Won Park, Hyungshin Yim

Exp Mol Med· April 2022

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PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma.
Hay-Ran Jang, Sol-Bi Shin, Chang-Hyeon Kim, Jae-Yeon Won, Rong Xu, Hyungshin Yim

Cell Death Differ· September 2021

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Dual Targeting of EGFR with PLK1 Exerts Therapeutic Synergism in Taxane-Resistant Lung Adenocarcinoma by Suppressing ABC Transporters.
Sol-Bi Shin, Dae-Hoon Kim, Da-Eun Kim, Mark Borris D Aldonza, Yoosik Kim, Hyungshin Yim

Cancers (Basel)· September 2021

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Combination of Inhibitors of USP7 and PLK1 has a Strong Synergism against Paclitaxel Resistance.
Sol-Bi Shin, Chang-Hyeon Kim, Hay-Ran Jang, Hyungshin Yim

Int J Mol Sci· November 2020

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CRISPR-mediated promoter de/methylation technologies for gene regulation.
Chang K Sung, Hyungshin Yim

Arch Pharm Res· July 2020

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Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer.
Sol-Bi Shin, Hay-Ran Jang, Rong Xu, Jae-Yeon Won, Hyungshin Yim

Oncogene· January 2020

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Correction: Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer.
Sol-Bi Shin, Hay-Ran Jang, Rong Xu, Jae-Yeon Won, Hyungshin Yim

Oncogene· January 2020

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Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21.
Min Sung Joo, Sol-Bi Shin, Eun Jung Kim, Ja Hyun Koo, Hyungshin Yim

FASEB J· July 2019

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Roles of the Phosphorylation of Transcriptional Factors in Epithelial-Mesenchymal Transition.
Rong Xu, Jae-Yeon Won, Chang-Hyeon Kim, Da-Eun Kim, Hyungshin Yim

J Oncol· June 2019

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Molecular Targets of Genistein and Its Related Flavonoids to Exert Anticancer Effects.
Hee-Sung Chae, Rong Xu, Jae-Yeon Won, Young-Won Chin, Hyungshin Yim

Int J Mol Sci· May 2019

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Cotargeting Plk1 and androgen receptor enhances the therapeutic sensitivity of paclitaxel-resistant prostate cancer.
Sol-Bi Shin, Sang-Uk Woo, Hyungshin Yim

Ther Adv Med Oncol· May 2019

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7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells.
Sang-Uk Woo, Hay-Ran Jang, Young-Won Chin, Hyungshin Yim

Planta Med· February 2019

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53BP1: A guardian for centrosomal integrity.
Haeyoung Kim, Hyungshin Yim

Front Biosci (Landmark Ed)· January 2018

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Oligopeptide Competition Assay for Phosphorylation Site Determination.
Min Sung Joo, Ja Hyun Koo, Sol-Bi Shin, Hyungshin Yim, Sang Geon Kim

J Vis Exp· May 2017

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Comparative Analysis of a FRET-based PLK1 Kinase Assay to Identify PLK1 inhibitors for Chemotherapy.
Sol-Bi Shin, Sang-Uk Woo, Young-Joo Lee, Hyungshin Yim

Anticancer Res· March 2017

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