Publications by authors named "Ian Barrett"

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The role of graph topology in the performance of biomedical Knowledge Graph Completion models.
Alberto Cattaneo, Stephen Bonner, Thomas Martynec, Edward Morrissey, Carlo Luschi, Ian P Barrett

Bioinformatics· October 2025

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Network-Based Approaches for Drug Target Identification.
Thodoris Koutsandreas, Kalliopi Tsafou, Heiko Horn, Ian Barrett, Evangelia Petsalaki

Annu Rev Biomed Data Sci· August 2025

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Multi-omic analysis reveals VEGFR2, PI3K, and JNK mediate the small molecule induction of human iPSC-derived cardiomyocyte proliferation.
Laura A Woo, Kaitlyn L Wintruba, Bethany Wissmann, Svyatoslav Tkachenko, Ewa Kubicka, Ian Barrett

iScience· August 2024

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Small Gene Networks Delineate Immune Cell States and Characterize Immunotherapy Response in Melanoma.
Donagh Egan, Martina Kreileder, Myriam Nabhan, Luis F Iglesias-Martinez, Simon J Dovedi, Ian P Barrett

Cancer Immunol Res· August 2023

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A Knowledge Graph-Enhanced Tensor Factorisation Model for Discovering Drug Targets.
Cheng Ye, Rowan Swiers, Stephen Bonner, Ian Barrett

IEEE/ACM Trans Comput Biol Bioinform· April 2023

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A review of biomedical datasets relating to drug discovery: a knowledge graph perspective.
Stephen Bonner, Ian P Barrett, Cheng Ye, Rowan Swiers, Ola Engkvist

Brief Bioinform· November 2022

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Implications of topological imbalance for representation learning on biomedical knowledge graphs.
Stephen Bonner, Ufuk Kirik, Ola Engkvist, Jian Tang, Ian P Barrett

Brief Bioinform· September 2022

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Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic Signature.
Maria-Anna Trapotsi, Elizabeth Mouchet, Guy Williams, Tiziana Monteverde, Karolina Juhani, Ian Barrett

ACS Chem Biol· July 2022

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Probabilistic Random Forest improves bioactivity predictions close to the classification threshold by taking into account experimental uncertainty.
Lewis H Mervin, Maria-Anna Trapotsi, Avid M Afzal, Ian P Barrett, Andreas Bender

J Cheminform· August 2021

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Signaling Dynamics Regulating Crosstalks between T-Cell Activation and Immune Checkpoints.
Martina Kreileder, Ian Barrett, Claus Bendtsen, Donal Brennan, Walter Kolch

Trends Cell Biol· March 2021

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Comparison of Chemical Structure and Cell Morphology Information for Multitask Bioactivity Predictions.
Maria-Anna Trapotsi, Lewis H Mervin, Avid M Afzal, Noé Sturm, Ola Engkvist, Ian P Barrett

J Chem Inf Model· March 2021

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New Associations between Drug-Induced Adverse Events in Animal Models and Humans Reveal Novel Candidate Safety Targets.
Kathryn A Giblin, Danilo Basili, Avid M Afzal, Lyn Rosenbrier-Ribeiro, Nigel Greene, Ian Barrett

Chem Res Toxicol· February 2021

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Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach.
Lauren Drowley, Jane McPheat, Anneli Nordqvist, Samantha Peel, Ulla Karlsson, Ian Barrett

Stem Cells Transl Med· January 2020

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Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.
Elliot J Lee, Aakil Patel, Rey R Acedillo, Jovina C Bachynski, Ian Barrett

Can J Kidney Health Dis· December 2019

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Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.
Richard J Mills, Benjamin L Parker, Gregory A Quaife-Ryan, Holly K Voges, Elise J Needham, Ian P Barrett

Cell Stem Cell· June 2019

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High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.
Laura A Woo, Svyatoslav Tkachenko, Mei Ding, Alleyn T Plowright, Ola Engkvist, Ian Barrett

J Mol Cell Cardiol· February 2019

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Safety and Efficacy of Intraoperative Computer-Navigated Versus Non-Navigated Shoulder Arthroplasty at a Tertiary Referral.
Ian Barrett, Anna Ramakrishnan, Emilie Cheung

Orthop Clin North Am· January 2019

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Short- to mid-term outcomes of anatomic MCL reconstruction with Achilles tendon allograft after multiligament knee injury.
Ian J Barrett, Aaron J Krych, Ayoosh Pareek, Nicholas R Johnson, Diane L Dahm

Knee Surg Sports Traumatol Arthrosc· October 2018

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Validation of Neck-Shaft Angle Correction After Cephalomedullary Nail Fixation.
Joshua A Parry, Ian Barrett, Bradley Schoch, William Cross, Brandon Yuan

J Orthop Trauma· October 2018

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Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.
Jeremy Karlin, Jasmine Allen, Syed F Ahmad, Gareth Hughes, Victoria Sheridan, Ian P Barrett

Mol Cancer Ther· August 2018

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The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Stephen T Durant, Li Zheng, Yingchun Wang, Kan Chen, Lingli Zhang, Ian Barrett

Sci Adv· June 2018

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Does the Angle of the Nail Matter for Pertrochanteric Fracture Reduction? Matching Nail Angle and Native Neck-Shaft Angle.
Joshua A Parry, Ian Barrett, Bradley Schoch, Brandon Yuan, Joseph Cass

J Orthop Trauma· April 2018

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Orthologue chemical space and its influence on target prediction.
Lewis H Mervin, Krishna C Bulusu, Leen Kalash, Avid M Afzal, Fredrik Svensson, Ian Barrett

Bioinformatics· January 2018

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Clinician's Commentary on Parsons et al..
Ian R Barrett

Physiother Can· January 2018

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Construct Rigidity: Keystone for Treating Pelvic Discontinuity.
J Ryan Martin, Ian Barrett, Rafael J Sierra, David G Lewallen, Daniel J Berry

J Bone Joint Surg Am· May 2017

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