Publications by authors named "Ian Cowell"

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A Detailed Analysis of How Physiotherapists "Give" Reassurance for Patients' Concerns in Back Pain Consultations.
Ian Cowell, Alison McGregor, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton

Qual Health Res· June 2025

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Topoisomerase II DNA Cleavage Assay Using Fluorescently Labelled Double-Stranded Oligonucleotides.
Ian G Cowell, Elise M Ling, Caroline A Austin

Methods Mol Biol· May 2025

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TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells.
Erica M Hildebrand, Ian G Cowell, Mushtaq M Khazeem, Snehal Sambare, Ozgun Uyan

Chromosome Res· April 2025

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Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti-cancer drug etoposide.
Ian G Cowell, Caroline A Austin

FEBS Open Bio· June 2024

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To Break or Not to Break: The Role of TOP2B in Transcription.
Ian G Cowell, John W Casement, Caroline A Austin

Int J Mol Sci· September 2023

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Physiotherapists' perceptions on using a multidimensional clinical reasoning form during psychologically informed training for low back pain.
Ian Cowell, Alison McGregor, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton

Musculoskelet Sci Pract· August 2023

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DNA fragility at the / locus: insights from old and new technologies.
Ian G Cowell, Caroline A Austin

Open Biol· January 2023

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TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells.
Mushtaq M Khazeem, John W Casement, George Schlossmacher, Niall S Kenneth, Nielda K Sumbung, Ian G Cowell

Mol Neurobiol· October 2022

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Two type I topoisomerases maintain DNA topology in human mitochondria.
Katja E Menger, James Chapman, Héctor Díaz-Maldonado, Mushtaq M Khazeem, Dasha Deen, Ian G Cowell

Nucleic Acids Res· October 2022

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A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Elise M Ling, Arnaud Baslé, Ian G Cowell, Bert van den Berg, Tim R Blower

Structure· August 2022

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Disease-associated mutations in topoisomerase IIβ result in defective NK cells.
Lori Broderick, Gwendolyn M Clay, Robert H Blum, Yang Liu, Rachael McVicar, Ian G Cowell

J Allergy Clin Immunol· June 2022

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Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent Complexes.
Rebecca L Swan, Ian G Cowell, Caroline A Austin

Mol Pharmacol· January 2022

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TOP2B's contributions to transcription.
Caroline A Austin, Ian G Cowell, Mushtaq M Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans· December 2021

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Physiotherapists' Approaches to Patients' Concerns in Back Pain Consultations Following a Psychologically Informed Training Program.
Ian Cowell, Alison McGregor, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton

Qual Health Res· November 2021

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A Role for VCP/p97 in the Processing of Drug-Stabilized TOP2-DNA Covalent Complexes.
Rebecca L Swan, Ian G Cowell, Caroline A Austin

Mol Pharmacol· July 2021

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How do physiotherapists solicit and explore patients' concerns in back pain consultations: a conversation analytic approach.
Ian Cowell, Alison McGregor, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton

Physiother Theory Pract· June 2021

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Transcription of carbonyl reductase 1 is regulated by DNA topoisomerase II beta.
Mushtaq M Khazeem, Ian G Cowell, Lauren F Harkin, John W Casement, Caroline A Austin

FEBS Lett· October 2020

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Small Molecule Inhibitors Confirm Ubiquitin-Dependent Removal of TOP2-DNA Covalent Complexes.
Rebecca L Swan, Luke L K Poh, Ian G Cowell, Caroline A Austin

Mol Pharmacol· September 2020

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The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison.
Ian G Cowell, Elise M Ling, Rebecca L Swan, Matilda L W Brooks, Caroline A Austin

Mol Pharmacol· November 2019

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Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations.
Mandeep Atwal, Rebecca L Swan, Chloe Rowe, Ka C Lee, David C Lee, Ian G Cowell

Mol Pharmacol· October 2019

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Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Lori Broderick, Shawn Yost, Dong Li, Matthew D McGeough, Laela M Booshehri, Ian G Cowell

Nat Commun· August 2019

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The perspectives of physiotherapists on managing nonspecific low back pain following a training programme in cognitive functional therapy: A qualitative study.
Ian Cowell, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton, Alison McGregor

Musculoskeletal Care· March 2019

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Perceptions of physiotherapists towards the management of non-specific chronic low back pain from a biopsychosocial perspective: A qualitative study.
Ian Cowell, Peter O'Sullivan, Kieran O'Sullivan, Ross Poyton, Alison McGregor

Musculoskelet Sci Pract· December 2018

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TOP2B: The First Thirty Years.
Caroline A Austin, Ka C Lee, Rebecca L Swan, Mushtaq M Khazeem, Catriona M Manville, Ian G Cowell

Int J Mol Sci· September 2018

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Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
Ka Cheong Lee, Rebecca L Swan, Zbyslaw Sondka, Kay Padget, Ian G Cowell

Int J Mol Sci· July 2018

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