Publications by authors named "Ian Lobb"

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USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.
Anamarija Jurisic, Pei-Ju Sung, Mark Wappett, Julien Daubriac, Ian T Lobb

Clin Transl Med· April 2024

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Oxidation modulates LINGO2-induced inactivation of large conductance, Ca-activated potassium channels.
Srikanth Dudem, Pei Xin Boon, Nicholas Mullins, Heather McClafferty, Michael J Shipston, Ian Lobb

J Biol Chem· March 2023

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SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships.
Mark Wappett, Adam Harris, Alexander L R Lubbock, Ian Lobb, Simon McDade

Nucleic Acids Res· July 2021

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The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes.
Brian M Ortmann, Natalie Burrows, Ian T Lobb, Esther Arnaiz, Niek Wit

Nat Genet· July 2021

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A Role for the Autophagic Receptor, SQSTM1/p62, in Trafficking NF-κB/RelA to Nucleolar Aggresomes.
Ian T Lobb, Pierre Morin, Kirsty Martin, Hazel C Thoms, Jimi C Wills

Mol Cancer Res· February 2021

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Endogenous HS production deficiencies lead to impaired renal erythropoietin production.
Jennifer Leigh, Smriti Juriasingani, Masoud Akbari, Peng Shao, Manujendra N Saha, Ian Lobb

Can Urol Assoc J· July 2019

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Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway.
Jingyu Chen, Ian T Lobb, Pierre Morin, Sonia M Novo, James Simpson

Nucleic Acids Res· July 2018

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A Hibernation-Like State for Transplantable Organs: Is Hydrogen Sulfide Therapy the Future of Organ Preservation?
George J Dugbartey, Hjalmar R Bouma, Manujendra N Saha, Ian Lobb, Robert H Henning

Antioxid Redox Signal· June 2018

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Daily therapy with a slow-releasing HS donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction.
Shouzhe Lin, Dameng Lian, Weihua Liu, Aaron Haig, Ian Lobb

Nitric Oxide· June 2018

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MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.
Sandra Stefanovic-Barrett, Anna S Dickson, Stephen P Burr, James C Williamson, Ian T Lobb

EMBO Rep· May 2018

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A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model.
Daniel Olvera-Posada, Shouzhe Lin, Ghaleb Aboalsamh, Aaron Haig, Ian Lobb

Can Urol Assoc J· October 2017

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GYY4137, a Slow-Releasing Hydrogen Sulfide Donor, Ameliorates Renal Damage Associated with Chronic Obstructive Uropathy.
Shouzhe Lin, Fazil Visram, Weihua Liu, Aaron Haig, Jifu Jiang, Ian Lobb

J Urol· December 2016

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Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.
Stephen P Burr, Ana S H Costa, Guinevere L Grice, Richard T Timms, Ian T Lobb

Cell Metab· November 2016

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Hydrogen Sulfide Induced Erythropoietin Synthesis is Regulated by HIF Proteins.
Jennifer Leigh, Manujendra N Saha, Amy Mok, Omar Champsi, Rui Wang, Ian Lobb

J Urol· July 2016

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Hydrogen sulfide: A novel nephroprotectant against cisplatin-induced renal toxicity.
George J Dugbartey, Hjalmar R Bouma, Ian Lobb, Alp Sener

Nitric Oxide· July 2016

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Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation.
Ian Lobb, Michael Davison, David Carter, Weihua Liu, Aaron Haig

J Urol· December 2015

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Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential.
Eric Sonke, Megan Verrydt, Carl O Postenka, Siddika Pardhan, Chantalle J Willie, Ian Lobb

Nitric Oxide· September 2015

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The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains.
Guinevere L Grice, Ian T Lobb, Michael P Weekes, Steven P Gygi, Robin Antrobus

Cell Rep· July 2015

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Hydrogen sulfide treatment ameliorates long-term renal dysfunction resulting from prolonged warm renal ischemia-reperfusion injury.
Ian Lobb, Justin Zhu, Weihua Liu, Aaron Haig, Zhu Lan

Can Urol Assoc J· May 2014

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Detrimental effects of prolonged warm renal ischaemia-reperfusion injury are abrogated by supplemental hydrogen sulphide: an analysis using real-time intravital microscopy and polymerase chain reaction.
Justin X G Zhu, Melanie Kalbfleisch, Yi Xin Yang, Relka Bihari, Ian Lobb

BJU Int· December 2012

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Supplemental hydrogen sulphide protects transplant kidney function and prolongs recipient survival after prolonged cold ischaemia-reperfusion injury by mitigating renal graft apoptosis and inflammation.
Ian Lobb, Amy Mok, Zhu Lan, Weihua Liu, Bertha Garcia

BJU Int· December 2012

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