Publications by authors named "Ian MacFawn"

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TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma.
Jessica D Daley, Elina Mukherjee, David Ferraro, A Carolina Tufino, Nathanael Bailey, Ian MacFawn

Cancer Res Commun· August 2025

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Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation.
Geyon L Garcia, Taylor Orellana, Grace Gorecki, Leonard Frisbie, Roja Baruwal, Ian P MacFawn

Cancer Discov· June 2025

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Past failures and new horizons: the nuances of tertiary lymphoid structures in high-grade serous ovarian cancer may contribute to immunotherapy effectiveness.
Rufiaat Rashid, Lan Coffman, Tullia C Bruno, Ian MacFawn

J Immunother Cancer· April 2025

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Dysfunctional CD11cCD21 extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer.
Ayana T Ruffin, Allison N Casey, Sheryl R Kunning, Ian P MacFawn, Zhentao Liu

Sci Transl Med· February 2025

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Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer.
Raphaël Mattiuz, Jesse Boumelha, Pauline Hamon, Jessica Le Berichel, Abishek Vaidya, Ian P MacFawn

bioRxiv· December 2024

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The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions.
Ian P MacFawn, Grant Magnon, Grace Gorecki, Sheryl Kunning, Rufiaat Rashid

Cancer Cell· November 2024

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Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence.
Ian MacFawn, Joshua Farris, Phillip Pifer, Naira V Margaryan, Halima Akhter

Mol Immunol· June 2024

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Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation.
Jessica D Daley, Elina Mukherjee, A Carolina Tufino, Nathanael Bailey, Shanthi Bhaskar, Ian MacFawn

bioRxiv· May 2024

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Stromal mediated DNA damage promotes high grade serous ovarian cancer initiation.
Geyon L Garcia, Taylor Orellana, Grace Gorecki, Leonard G Frisbie, Roja Baruwal, Ian P MacFawn

bioRxiv· May 2024

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Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes.
Lilit Karapetyan, Hassan M AbuShukair, Aofei Li, Andrew Knight, Ayah Nedal Al Bzour, Ian P MacFawn

Front Immunol· July 2023

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Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells.
Alyssa Vito, Omar Salem, Nader El-Sayes, Ian P MacFawn, Ana L Portillo

Commun Biol· July 2021

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Type I interferons and related pathways in cell senescence.
Steven M Frisch, Ian P MacFawn

Aging Cell· October 2020

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Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers.
Ian MacFawn, Hannah Wilson, Luke A Selth, Ian Leighton, Ilya Serebriiskii

Mol Immunol· January 2019

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