Publications by authors named "Ian Majewski"

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Uridine-cytidine kinase 2 potentiates the mutagenic influence of the antiviral β-d-N4-hydroxycytidine.
Zhen Xu, Christoffer Flensburg, Rebecca A Bilardi, Ian J Majewski

Nucleic Acids Res· December 2023

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Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition.
Hesham D Abdulla, Raed Alserihi, Christoffer Flensburg, Waruni Abeysekera, Meng-Xiao Luo, Ian J Majewski

J Exp Med· June 2023

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Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.
Rachel Thijssen, Luyi Tian, Mary Ann Anderson, Christoffer Flensburg, Andrew Jarratt, Ian J Majewski

Blood· November 2022

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Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.
Hu Fang, Helen H N Yan, Rebecca A Bilardi, Christoffer Flensburg, Haocheng Yang, Ian J Majewski

Genome Med· October 2022

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ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia.
Breon Schmidt, Lauren M Brown, Georgina L Ryland, Andrew Lonsdale, Hansen J Kosasih, Ian J Majewski

Blood Adv· July 2022

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Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.
Claire Palles, Hannah D West, Edward Chew, Sara Galavotti, Christoffer Flensburg, Ian J Majewski

Am J Hum Genet· May 2022

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Detecting copy number alterations in RNA-Seq using SuperFreq.
Christoffer Flensburg, Alicia Oshlack, Ian J Majewski

Bioinformatics· November 2021

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Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencing.
Luyi Tian, Jafar S Jabbari, Rachel Thijssen, Quentin Gouil, Shanika L Amarasinghe, Ian Majewski

Genome Biol· November 2021

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MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data.
Marek Cmero, Breon Schmidt, Ian J Majewski, Paul G Ekert, Alicia Oshlack

Genome Biol· October 2021

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The crux of Cux1 in myeloid neoplasms.
Ian J Majewski

Blood· September 2021

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CHK2 Inhibition Provides a Strategy to Suppress Hematologic Toxicity from PARP Inhibitors.
Zhen Xu, Cassandra J Vandenberg, Elizabeth Lieschke, Ladina Di Rago, Clare L Scott, Ian J Majewski

Mol Cancer Res· August 2021

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Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Rachel Thijssen, Sarah T Diepstraten, Donia Moujalled, Edward Chew, Christoffer Flensburg, Ian J Majewski

Blood· May 2021

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Finding a suitable library size to call variants in RNA-Seq.
Anna Quaglieri, Christoffer Flensburg, Terence P Speed, Ian J Majewski

BMC Bioinformatics· December 2020

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Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy.
Chong Chyn Chua, Andrew W Roberts, John Reynolds, Chun Yew Fong, Stephen B Ting, Ian J Majewski

J Clin Oncol· October 2020

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A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.
Joanne M Hildebrand, Maria Kauppi, Ian J Majewski, Zikou Liu, Allison J Cox

Nat Commun· June 2020

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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia.
Lauren M Brown, Andrew Lonsdale, Andrea Zhu, Nadia M Davidson, Breon Schmidt, Ian J Majewski

Blood Adv· March 2020

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SuperFreq: Integrated mutation detection and clonal tracking in cancer.
Christoffer Flensburg, Tobias Sargeant, Alicia Oshlack, Ian J Majewski

PLoS Comput Biol· February 2020

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Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia.
Lauren M Brown, Ray C Bartolo, Nadia M Davidson, Breon Schmidt, Ian Brooks, Ian J Majewski

Pediatr Blood Cancer· October 2019

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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Richard W Birkinshaw, Jia-Nan Gong, Cindy S Luo, Daisy Lio, Christine A White, Ian J Majewski

Nat Commun· June 2019

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On fitness: how do mutations shape the biology of cancer?
Ian J Majewski

Biochem Soc Trans· April 2019

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Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia.
Piers Blombery, Mary Ann Anderson, Jia-Nan Gong, Rachel Thijssen, Richard W Birkinshaw, Ian J Majewski

Cancer Discov· March 2019

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MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML.
Mathijs A Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E Miller, Ian J Majewski

Blood· October 2018

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Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines.
Katarzyna Jastrzebski, Bram Thijssen, Roelof J C Kluin, Klaas de Lint, Ian J Majewski

Cancer Res· August 2018

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Clinker: visualizing fusion genes detected in RNA-seq data.
Breon M Schmidt, Nadia M Davidson, Anthony D K Hawkins, Ray Bartolo, Ian J Majewski

Gigascience· July 2018

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BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming.
Esther J Y Kim, Minna-Liisa Anko, Christoffer Flensberg, Ian J Majewski, Fan-Suo Geng

Stem Cell Reports· February 2018

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