Publications by authors named "Ian R Kill"

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Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells.
Ishita S Mehta, Kumars Riyahi, Rita Torres Pereira, Karen J Meaburn, Martin Figgitt, Ian R Kill

Front Cell Dev Biol· May 2021

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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform.
Mehmet U Bikkul, Richard G A Faragher, Gemma Worthington, Peter Meinke, Alastair R W Kerr, Ian R Kill

Genes Chromosomes Cancer· June 2019

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Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.
Craig S Clements, Mehmet U Bikkul, Wendy Ofosu, Christopher Eskiw, David Tree, Ian R Kill

Biogerontology· June 2019

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Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts.
Mehmet U Bikkul, Craig S Clements, Lauren S Godwin, Martin W Goldberg, Ian R Kill

Biogerontology· December 2018

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Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/B-mediated cytokine production.
Zoe E Gillespie, Kimberly MacKay, Michelle Sander, Brett Trost, Wojciech Dawicki, Ian R Kill

Nucleus· November 2016

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A structured environment helps to regulate nuclear architecture in breast epithelial cells.
Joanna M Bridger, Ian R Kill

Cell Cycle· May 2016

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The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer.
Joanna M Bridger, Halime D Arican-Gotkas, Helen A Foster, Lauren S Godwin, Amanda Harvey, Ian R Kill

Adv Exp Med Biol· September 2014

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Progeria Research Day at Brunel University.
Joanna M Bridger, Christopher H Eskiw, Evgeny M Makarov, David Tree, Ian R Kill

Nucleus· May 2012

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Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.
Ishita S Mehta, Christopher H Eskiw, Halime D Arican, Ian R Kill, Joanna M Bridger

Genome Biol· August 2011

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Progeria, the nucleolus and farnesyltransferase inhibitors.
Ishita S Mehta, Joanna M Bridger, Ian R Kill

Biochem Soc Trans· February 2010

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The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts.
Richard G A Faragher, Ian R Kill

Biogerontology· June 2009

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Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?
Ishita S Mehta, Lauren S Elcock, Manelle Amira, Ian R Kill, Joanna M Bridger

Biochem Soc Trans· December 2008

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Towards a Drosophila model of Hutchinson-Gilford progeria syndrome.
Gemma S Beard, Joanna M Bridger, Ian R Kill, David R P Tree

Biochem Soc Trans· December 2008

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Primary laminopathy fibroblasts display altered genome organization and apoptosis.
Karen J Meaburn, Erik Cabuy, Gisele Bonne, Nicolas Levy, Glenn E Morris, Ian R Kill

Aging Cell· April 2007

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Alterations to nuclear architecture and genome behavior in senescent cells.
Ishita S Mehta, Martin Figgitt, Craig S Clements, Ian R Kill, Joanna M Bridger

Ann N Y Acad Sci· April 2007

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The nuclear lamina. Both a structural framework and a platform for genome organization.
Joanna M Bridger, Nicole Foeger, Ian R Kill, Harald Herrmann

FEBS J· March 2007

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Heterogeneity of dimer excision in young and senescent human dermal fibroblasts.
Jennifer Boyle, Ian R Kill, Christopher N Parris

Aging Cell· October 2005

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Analysis of UV-induced damage and repair in young and senescent human dermal fibroblasts using the comet assay.
Eman A Al-Baker, Michael Oshin, Christopher J Hutchison, Ian R Kill

Mech Ageing Dev· September 2005

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Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis.
Joanna M Bridger, Ian R Kill

Exp Gerontol· May 2004

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A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation.
Eman Ali Al-Baker, Jennifer Boyle, Rachel Harry, Ian R Kill

Exp Cell Res· January 2004

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