Publications by authors named "Ian Semple"

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Sestrins are evolutionarily conserved mediators of exercise benefits.
Myungjin Kim, Alyson Sujkowski, Sim Namkoong, Bondong Gu, Tyler Cobb, Ian Semple

Nat Commun· January 2020

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Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury.
Chun-Seok Cho, Allison H Kowalsky, Sim Namkoong, Sung-Rye Park, Shuangcheng Wu, Ian A Semple

Cell Discov· November 2019

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Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity.
Ruiting Li, Yin Huang, Ian Semple, Myungjin Kim, Zunjian Zhang

Am J Physiol Heart Circ Physiol· July 2019

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Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation.
Chun-Seok Cho, Hwan-Woo Park, Allison Ho, Ian A Semple, Boyoung Kim

Hepatology· October 2018

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Autophagy Dysregulation and Obesity-Associated Pathologies.
Sim Namkoong, Chun-Seok Cho, Ian Semple, Jun Hee Lee

Mol Cells· January 2018

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Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.
Myungjin Kim, Ian Semple, Boyoung Kim, Alexandra Kiers, Samuel Nam

Autophagy· June 2016

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Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.
Seung-Hyun Ro, Xiang Xue, Sadeesh K Ramakrishnan, Chun-Seok Cho, Sim Namkoong, Ian A Semple

Elife· February 2016

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Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Myungjin Kim, Erin Sandford, Damian Gatica, Yu Qiu, Xu Liu, Ian Semple

Elife· January 2016

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Corrigendum: Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
Jeong Sig Kim, Seung-Hyun Ro, Myungjin Kim, Hwan-Woo Park, Ian A Semple

Sci Rep· September 2015

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Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue.
Seung-Hyun Ro, Ian Semple, Allison Ho, Hwan-Woo Park, Jun Hee Lee

Front Endocrinol (Lausanne)· August 2015

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Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
Jeong Sig Kim, Seung-Hyun Ro, Myungjin Kim, Hwan-Woo Park, Ian A Semple

Sci Rep· March 2015

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Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1.
Seung-Hyun Ro, Ian A Semple, Haewon Park, Haeli Park, Hwan-Woo Park

FEBS J· September 2014

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Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers.
Hwan-Woo Park, Haeli Park, Ian A Semple, Insook Jang, Seung-Hyun Ro

Nat Commun· September 2014

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Hepatoprotective role of Sestrin2 against chronic ER stress.
Hwan-Woo Park, Haeli Park, Seung-Hyun Ro, Insook Jang, Ian A Semple

Nat Commun· June 2014

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Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species.
Seung-Hyun Ro, Myeongjin Nam, Insook Jang, Hwan-Woo Park, Haeli Park, Ian A Semple

Proc Natl Acad Sci U S A· May 2014

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