Publications by authors named "Ian T Pyrah"

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High hematocrit resulting from administration of erythropoiesis-stimulating agents is not fully predictive of mortality or toxicities in preclinical species.
Dina A Andrews, Ian T G Pyrah, Babette M Boren, Sarah H Tannehill-Gregg, Ruth M Lightfoot-Dunn

Toxicol Pathol· December 2014

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Dose-related differences in the pharmacodynamic and toxicologic response to a novel hyperglycosylated analog of recombinant human erythropoietin in Sprague-Dawley rats with similarly high hematocrit.
Dina A Andrews, Babette M Boren, James R Turk, Rogely W Boyce, Yudong D He, Ian T G Pyrah

Toxicol Pathol· December 2014

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Cytokines associated with increased erythropoiesis in Sprague-Dawley rats administered a novel hyperglycosylated analog of recombinant human erythropoietin.
Dina A Andrews, Hisham K Hamadeh, Yudong D He, Babette M Boren, James R Turk, Ian T G Pyrah

Toxicol Pathol· December 2014

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Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy.
Graeme J Moffat, Rhian Davies, Gayle Kwon, Marc W Retter, Gary J Chellman, Ian T G Pyrah

Reprod Toxicol· September 2014

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Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.
Rogely W Boyce, Aurore Varela, Luc Chouinard, Jeanine L Bussiere, Gary J Chellman, Ian T Pyrah

Bone· July 2014

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Dual inhibition of VEGFR and EGFR signaling reduces the incidence and size of intestinal adenomas in Apc(Min/+) mice.
Denis Alferez, Robert W Wilkinson, Jim Watkins, Richard Poulsom, Nikki Mandir, Ian T Pyrah

Mol Cancer Ther· March 2008

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Review of the application of RNA interference technology in the pharmaceutical industry.
Henny M Martineau, Ian T Pyrah

Toxicol Pathol· April 2007

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