Publications by authors named "Iara Backes"

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Eliminating interactions with the viral Fc receptor improves antibody-mediated protection against neonatal HSV infection in mice.
Matthew D Slein, Iara M Backes, Lesle M Jiménez, Natasha S Kelkar, Callaghan R Garland

Sci Transl Med· November 2025

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Antibodies targeting HSV glycoprotein B require effector functions to protect neonatal mice.
Matthew D Slein, Lesle M Jiménez, Iara M Backes, Evelyn M Turnbaugh, Callaghan R Garland

bioRxiv· July 2025

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Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI.
Matthew D Slein, Iara M Backes, Natasha S Kelkar, Callaghan R Garland, Urjeet S Khanwalkar

bioRxiv· November 2024

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Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D.
Matthew D Slein, Iara M Backes, Callaghan R Garland, Natasha S Kelkar, David A Leib

Cell Rep Med· February 2024

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Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection.
Matthew D Slein, Iara M Backes, Callaghan R Garland, Natasha S Kelkar, David A Leib

bioRxiv· August 2023

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Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates.
Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M Backes

mBio· April 2023

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Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity.
Iara M Backes, Brook K Byrd, Matthew D Slein, Chaya D Patel, Sean A Taylor

J Exp Med· December 2022

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Monoclonal antibody therapy of herpes simplex virus: An opportunity to decrease congenital and perinatal infections.
Iara M Backes, David A Leib, Margaret E Ackerman

Front Immunol· August 2022

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Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.
Thach H Chu, Andrew R Crowley, Iara Backes, Cheryl Chang, Matthew Tay

PLoS Pathog· February 2020

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Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity.
Chaya D Patel, Iara M Backes, Sean A Taylor, Yike Jiang, Arnaud Marchant

Sci Transl Med· April 2019

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Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease.
Yike Jiang, Chaya D Patel, Richard Manivanh, Brian North, Iara M Backes

mBio· July 2017

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Brain-derived neurotrophic factor modulates angiotensin signaling in the hypothalamus to increase blood pressure in rats.
Benedek Erdos, Iara Backes, Michael L McCowan, Linda F Hayward, Deborah A Scheuer

Am J Physiol Heart Circ Physiol· March 2015

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