Publications by authors named "Ida Hilden"

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A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Henrik Østergaard, Jacob Lund, Per J Greisen, Stine Kjellev, Anette Henriksen, Ida Hilden

Blood· October 2021

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Thrombin generation potential in the presence of concizumab and rFVIIa, APCC, rFVIII, or rFIX: In vitro and ex vivo analyses.
Marianne Kjalke, Mads Kjelgaard-Hansen, Søren Andersen, Ida Hilden

J Thromb Haemost· July 2021

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Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.
Mari Enoksson, Erika J Martin, Heidi Holmberg, Mette S Jensen, Mads Kjelgaard-Hansen, Ida Hilden

J Thromb Haemost· January 2020

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Measurement of plasma and platelet tissue factor pathway inhibitor, factor V and Protein S in people with haemophilia.
Paul E R Ellery, Ida Hilden, Peter Thyregod, Nicholas D Martinez, Susan A Maroney

Haemophilia· November 2019

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Concizumab promotes haemostasis via a tissue factor-factor VIIa-dependent mechanism supporting prophylactic treatment of haemophilia: Results from a rabbit haemophilia bleeding model.
Brian Lauritzen, Ida Hilden

Haemophilia· November 2019

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Administration of recombinant FVIIa (rFVIIa) to concizumab-dosed monkeys is safe, and concizumab does not affect the potency of rFVIIa in hemophilic rabbits.
Brian Lauritzen, Janne Olling, Kristin L Abel, Cecilia Augustsson, Kristoffer Balling, Ida Hilden

J Thromb Haemost· March 2019

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Correlates of plasma and platelet tissue factor pathway inhibitor, factor V, and Protein S.
Paul E R Ellery, Ida Hilden, Ken Sejling, Mette Loftager, Nicholas D Martinez

Res Pract Thromb Haemost· January 2018

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TFPIα interacts with FVa and FXa to inhibit prothrombinase during the initiation of coagulation.
Jeremy P Wood, Helle H Petersen, Bingke Yu, Xiaoai Wu, Ida Hilden

Blood Adv· December 2017

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Inhibitory effects of LDL-associated tissue factor pathway inhibitor.
Cecilia Augustsson, Ida Hilden, Lars C Petersen

Thromb Res· July 2014

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Pharmacokinetics of an anti-TFPI monoclonal antibody (concizumab) blocking the TFPI interaction with the active site of FXa in Cynomolgus monkeys after iv and sc administration.
Henrik Agersø, Rune Viig Overgaard, Mads Bjelke Petersen, Lene Hansen, Mette Brunsgaard Hermit, Ida Hilden

Eur J Pharm Sci· June 2014

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Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor.
Lene Hansen, Lars Christian Petersen, Brian Lauritzen, Jes Thorn Clausen, Susanne Nedergaard Grell, Ida Hilden

Thromb Res· March 2014

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A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.
Henning R Stennicke, Marianne Kjalke, Ditte M Karpf, Kristoffer W Balling, Peter B Johansen, Ida Hilden

Blood· March 2013

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Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.
Ida Hilden, Brian Lauritzen, Brit Binow Sørensen, Jes Thorn Clausen, Christina Jespersgaard

Blood· June 2012

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Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1).
Cristina Ionica Øie, Rupa Shree Appa, Ida Hilden, Helle Heibroch Petersen, Albrecht Gruhler

J Hepatol· December 2011

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Regulation of thrombin generation by TFPI in plasma without and with heparin.
Ellen Brodin, Hege Appelbom, Bjarne Osterud, Ida Hilden, Lars C Petersen

Transl Res· March 2009

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