Publications by authors named "Igor A Butovich"

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Abnormal meibum is associated with SREBF1 mutation and IFAP Syndrome-2.
Igor A Butovich, Martha Schatz, Ujwala S Saboo, Jadwiga C Wojtowicz, Daniel A Johnson

Exp Eye Res· January 2026

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Lipid Composition and Thermotropic Properties of Meibum of Animal Models and Humans with Meibomian Gland Dysfunction.
Igor A Butovich, Jadwiga C Wojtowicz, Amber Wilkerson, Seher Yuksel

Int J Mol Sci· November 2025

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Abnormal Meibum Is Associated With Mutation And IFAP Syndrome-2.
Igor A Butovich, Martha Schatz, Ujwala S Saboo, Jadwiga C Wojtowicz, Daniel A Johnson

medRxiv· October 2025

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Aging Affects Lipid Homeostasis in Lacrimal Glands by Upregulating Lipogenesis and Changing Its Specificity.
Seher Yuksel, Prashant Kumar, Sydney E Krenz, Kaitlin K Scholand, Zhiyuan Yu, Igor A Butovich

Invest Ophthalmol Vis Sci· October 2025

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Lipid composition determines thermotropic properties of meibum of animals and humans with Meibomian gland disorders.
Igor A Butovich, Jadwiga C Wojtowicz, Amber Wilkerson, Seher Yuksel

bioRxiv· August 2025

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Biosynthesis of fatty aldehydes and alcohols in the eye and their role in meibogenesis.
Seher Yuksel, Igor A Butovich

J Biol Chem· July 2025

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Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression.
Sudhir Verma, Paola A Guevara Montoya, Mingxia Sun, Sudan Puri, Seher Yuksel, Igor A Butovich

Invest Ophthalmol Vis Sci· July 2025

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Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease.
Erin A Hisey, Sydni Wong, Sangwan Park, Kevin Aguirre Gamarra, Sara A Adelman, Igor A Butovich

Ocul Surf· October 2024

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Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface.
Amber Wilkerson, Seher Yuksel, Riya Acharya, Igor A Butovich

Invest Ophthalmol Vis Sci· July 2024

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Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology.
Yuqiuhe Liu, Igor A Butovich, Fabian Garreis, Ingrid Zahn, Michael Scholz

Int J Mol Sci· March 2024

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Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1-Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease.
Xiaojie Xu, Amber Wilkerson, Guangle Li, Igor A Butovich, Yi Y Zuo

Invest Ophthalmol Vis Sci· August 2023

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Dysregulation of Lipid Metabolism in Aging Meibomian Glands and Its Molecular Markers.
Igor A Butovich, Amber Wilkerson, Seher Yuksel

Int J Mol Sci· August 2023

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Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis.
Igor A Butovich, Amber Wilkerson, Kelli R Goggans, Olga V Belyaeva, Natalia Y Kedishvili

J Biol Chem· June 2023

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Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis.
Seher Yuksel, Bogale Aredo, Yeshumenesh Zegeye, Cynthia X Zhao, Miao Tang, Igor A Butovich

Commun Biol· May 2023

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Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography-tandem mass spectrometry study.
Igor A Butovich, Seher Yuksel, Amber Wilkerson

J Biol Chem· April 2023

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Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition.
Céline Portal, Yvonne Lin, Varuni Rastogi, Cornelia Peterson, Samuel Chi-Hung Yiu, Igor A Butovich

Commun Biol· March 2023

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Dynamic Changes in the Gene Expression Patterns and Lipid Profiles in the Developing and Maturing Meibomian Glands.
Igor A Butovich, Amber Wilkerson

Int J Mol Sci· July 2022

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Novel Lipids of the Rabbit Harderian Gland Improve Tear Stability in an Animal Model of Dry Eye Disease.
Igor A Butovich, Seher Yuksel, Brian Leonard, Tom Gadek, Arthur S Polans

J Ocul Pharmacol Ther· December 2021

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Effects of Aging on Human Meibum.
Igor A Butovich, Tomo Suzuki

Invest Ophthalmol Vis Sci· September 2021

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Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands.
Igor A Butovich, Amber Wilkerson, Seher Yuksel

J Steroid Biochem Mol Biol· July 2021

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Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a -Null Mouse Model.
Igor A Butovich, Amber Wilkerson, Seher Yuksel

Int J Mol Sci· February 2021

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Delineating a novel metabolic high triglycerides-low waxes syndrome that affects lipid homeostasis in meibomian and sebaceous glands.
Igor A Butovich, Tomo Suzuki

Exp Eye Res· October 2020

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Comprehensive profiling of Asian and Caucasian meibomian gland secretions reveals similar lipidomic signatures regardless of ethnicity.
Igor A Butovich, Tomo Suzuki, Jadwiga Wojtowicz, Nita Bhat, Seher Yuksel

Sci Rep· September 2020

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On the pivotal role of /ELOVL3 in meibogenesis and ocular physiology of mice.
Igor A Butovich, Amber Wilkerson, Nita Bhat, Anne McMahon, Seher Yuksel

FASEB J· September 2019

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Comparative Transcriptomic and Lipidomic Analyses of Human Male and Female Meibomian Glands Reveal Common Signature Genes of Meibogenesis.
Igor A Butovich, Nita Bhat, Jadwiga C Wojtowicz

Int J Mol Sci· September 2019

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