Publications by authors named "Igor A Schepetkin"

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c-Jun N-Terminal Kinase (JNK) Inhibitor IQ-1S as a Suppressor of Tumor Spheroid Growth.
Elena Afrimzon, Mordechai Deutsch, Maria Sobolev, Naomi Zurgil, Andrei I Khlebnikov, Igor A Schepetkin

Molecules· November 2025

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Activity-Based Profiling of Papain-like Cysteine Proteases During Late-Stage Leaf Senescence in Barley.
Igor A Schepetkin, Andreas M Fischer

Plants (Basel)· October 2025

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Design, Synthesis, and Biological Evaluation of Novel Heteroaryl, Squaramide, and Indolcarboxamide Derivatives as Formyl Peptide Receptor 2 Agonists to Target Neuroinflammation.
Fabio Francavilla, Daniele Vitone, Igor A Schepetkin, Lilya N Kirpotina, Antonio Carrieri

ACS Chem Neurosci· September 2025

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Hydrogen Sulfide (HS)-Donating Formyl Peptide Receptor 2 (FPR2) Agonists: Design, Synthesis, and Biological Evaluation in Primary Mouse Microglia Culture.
Leonardo Brunetti, Fabio Francavilla, Mauro Niso, Jakub Kosma Frydrych, Ewa Trojan, Igor A Schepetkin

Antioxidants (Basel)· July 2025

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Tricyclic Isatin Derivatives as Anti-Inflammatory Compounds with High Kinase Binding Affinity.
Alexander V Uvarov, Igor A Schepetkin, Mark T Quinn, Andrei I Khlebnikov

Molecules· July 2025

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Regulation of Blood-Brain Barrier Permeability via JNK Signaling Pathway: Mechanisms and Potential Therapeutic Strategies for Ischemic Stroke, Alzheimer's Disease and Brain Tumors.
Mark B Plotnikov, Anna M Anishchenko, Andrei I Khlebnikov, Igor A Schepetkin

Molecules· May 2025

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Development of small-molecule fluorescent probes targeting neutrophils -formyl peptide receptors.
Qi Xu, Kalwant S Authi, Liliya N Kirpotina, Igor A Schepetkin, Mark T Quinn

RSC Med Chem· March 2025

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Cathepsin B- and L-like Protease Activities Are Induced During Developmental Barley Leaf Senescence.
Igor A Schepetkin, Andreas M Fischer

Plants (Basel)· October 2024

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Evaluation of Nitric Oxide-Donating Properties of 11-indeno[1,2-]quinoxalin-11-one Oxime (IQ-1) by Electron Paramagnetic Resonance Spectroscopy.
Viacheslav V Andrianov, Igor A Schepetkin, Leah V Bazan, Khalil L Gainutdinov, Anastasia R Kovrizhina

Molecules· August 2024

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Phytochemical Composition and Biological Activity of the Essential Oil from Collected in Southwestern Montana, United States.
Igor A Schepetkin, Gulmira Özek, Temel Özek, Liliya N Kirpotina, Andrei I Khlebnikov

Plants (Basel)· July 2024

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Anti-Inflammatory Activity of Pyrazolo[1,5-]quinazolines.
Letizia Crocetti, Andrei I Khlebnikov, Gabriella Guerrini, Igor A Schepetkin, Fabrizio Melani

Molecules· May 2024

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Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity.
Letizia Crocetti, Francesca Catarzi, Maria Paola Giovannoni, Claudia Vergelli, Gianluca Bartolucci, Igor A Schepetkin

RSC Med Chem· April 2024

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Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models.
Fabio Francavilla, Federica Sarcina, Igor A Schepetkin, Lilya N Kirpotina, Marialessandra Contino

Eur J Med Chem· December 2023

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Volatile Composition, Antimicrobial Activity, and In Vitro Innate Immunomodulatory Activity of (L.) Moench Essential Oils.
Noura S Dosoky, Liliya N Kirpotina, Igor A Schepetkin, Andrei I Khlebnikov, Brent L Lisonbee

Molecules· October 2023

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Immunomodulatory Activity of Polysaccharides Isolated from L. and Ledeb.
Igor A Schepetkin, Marina G Danilets, Anastasia A Ligacheva, Evgenia S Trofimova, Natalia S Selivanova

Molecules· September 2023

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Composition and Biological Activity of the Essential Oils from Wild Horsemint, Yarrow, and Yampah from Subalpine Meadows in Southwestern Montana: Immunomodulatory Activity of Dillapiole.
Igor A Schepetkin, Gulmira Özek, Temel Özek, Liliya N Kirpotina, Robyn A Klein

Plants (Basel)· July 2023

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Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia.
Mark B Plotnikov, Galina A Chernysheva, Vera I Smol'yakova, Oleg I Aliev, Anna M Anishchenko, Igor A Schepetkin

Pharmaceuticals (Basel)· July 2023

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Novel Tryptanthrin Derivatives with Selectivity as -Jun N-Terminal Kinase (JNK) 3 Inhibitors.
Igor A Schepetkin, Oleksander S Karpenko, Anastasia R Kovrizhina, Liliya N Kirpotina, Andrei I Khlebnikov

Molecules· June 2023

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Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives.
Igor A Schepetkin, Zhangeldy S Nurmaganbetov, Serik D Fazylov, Oralgazy A Nurkenov, Andrei I Khlebnikov

Molecules· April 2023

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Cardioprotective Effects of a Selective c-Jun N-terminal Kinase Inhibitor in a Rat Model of Myocardial Infarction.
Mark B Plotnikov, Galina A Chernysheva, Vera I Smol'yakova, Oleg I Aliev, Tatyana I Fomina, Igor A Schepetkin

Biomedicines· February 2023

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Neutrophil Immunomodulatory Activity of Nerolidol, a Major Component of Essential Oils from Buds and Propolis.
Igor A Schepetkin, Gulmira Özek, Temel Özek, Liliya N Kirpotina, Polina I Kokorina

Plants (Basel)· December 2022

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Design, synthesis and biological evaluation of novel O-substituted tryptanthrin oxime derivatives as c-Jun -terminal kinase inhibitors.
Igor A Schepetkin, Anastasia R Kovrizhina, Ksenia S Stankevich, Andrei I Khlebnikov, Liliya N Kirpotina

Front Pharmacol· September 2022

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Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia-Reperfusion.
Igor A Schepetkin, Galina A Chernysheva, Oleg I Aliev, Liliya N Kirpotina, Vera I Smol'yakova

Biomedicines· August 2022

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Neutrophil Immunomodulatory Activity of (-)-Borneol, a Major Component of Essential Oils Extracted from .
Igor A Schepetkin, Gulmira Özek, Temel Özek, Liliya N Kirpotina, Andrei I Khlebnikov

Molecules· July 2022

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Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity.
Niccolo Cantini, Igor A Schepetkin, Nadezhda V Danilenko, Andrei I Khlebnikov, Letizia Crocetti

Molecules· June 2022

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