Publications by authors named "Igor Cestari"

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Identifying Trypanosoma cruzi Proteins Targeted by Chagas Disease Patient Antibodies Using Yeast Surface Display.
Mira Loock, Igor Cestari

Methods Mol Biol· November 2025

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Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection.
Lissa Cruz-Saavedra, Mira Loock, Luiza Berenguer Antunes, Igor Cestari

Nat Commun· November 2025

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Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes.
Luiza Berenguer Antunes, Tony Isebe, Oksana Kutova, Igor Cestari

Nat Commun· November 2025

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Helminth-derived metabolites induce tolerogenic functional, metabolic, and transcriptional signatures in dendritic cells that attenuate experimental colitis.
Nathalia L Malacco, Aubrey N Michi, Elizabeth Siciliani, Ana G Madrigal, Tamara Sternlieb, Igor Cestari

bioRxiv· August 2024

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Editorial: Cellular immune response and escape mechanisms of intracellular parasites.
Patrícia Maria Lourenço Dutra, Luciana Silva Rodrigues, Roberta Olmo Pinheiro, Wânia Ferraz Pereira Manfro, Igor Cestari

Front Immunol· January 2024

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Identifying Antigenic Switching by Clonal Cell Barcoding and Nanopore Sequencing in .
Abdoulie O Touray, Tamara Sternlieb, Tony Isebe, Igor Cestari

Bio Protoc· December 2023

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PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes.
Abdoulie O Touray, Rishi Rajesh, Tony Isebe, Tamara Sternlieb, Mira Loock, Igor Cestari

Elife· November 2023

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High-Efficiency Transformation and Expression of Genomic Libraries in Yeast.
Mira Loock, Luiza Berenguer Antunes, Rhiannon T Heslop, Antonio Alfonso De Lauri, Andressa Brito Lira, Igor Cestari

Methods Protoc· September 2023

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Genome-Wide Libraries for Protozoan Pathogen Drug Target Screening Using Yeast Surface Display.
Rhiannon Heslop, Mengjin Gao, Andressa Brito Lira, Tamara Sternlieb, Mira Loock, Igor Cestari

ACS Infect Dis· May 2023

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Erratum: Update Notice: Efficient Generation of Genome-wide Libraries for Protein-ligand Screens Using Gibson Assembly.
Tamara Sternlieb, Mira Loock, Mengjin Gao, Igor Cestari

Bio Protoc· May 2023

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Efficient Generation of Genome-wide Libraries for Protein-ligand Screens Using Gibson Assembly.
Tamara Sternlieb, Mira Loock, Mengjin Gao, Igor Cestari

Bio Protoc· November 2022

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The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets.
Fernando Altamura, Rishi Rajesh, Carolina M C Catta-Preta, Nilmar S Moretti, Igor Cestari

Drug Dev Res· April 2022

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Protein acetylation in the critical biological processes in protozoan parasites.
Suellen Rodrigues Maran, Krista Fleck, Natália Melquie Monteiro-Teles, Tony Isebe, Pegine Walrad, Igor Cestari

Trends Parasitol· September 2021

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ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in .
Paula Andrea Marin, Ricardo Obonaga, Raphael Souza Pavani, Marcelo Santos da Silva, Christiane Bezerra de Araujo, Igor Cestari

Front Cell Dev Biol· December 2020

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The phosphoinositide regulatory network in Trypanosoma brucei: Implications for cell-wide regulation in eukaryotes.
Igor Cestari, Kenneth Stuart

PLoS Negl Trop Dis· October 2020

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Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.
Inna Aphasizheva, Juan Alfonzo, Jason Carnes, Igor Cestari, Jorge Cruz-Reyes

Trends Parasitol· April 2020

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Phosphoinositide signaling and regulation in Trypanosoma brucei: Specialized functions in a protozoan pathogen.
Igor Cestari

PLoS Pathog· January 2020

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Plasmodium Secretion Induces Hepatocyte Lysosome Exocytosis and Promotes Parasite Entry.
Kamalakannan Vijayan, Igor Cestari, Fred D Mast, Elizabeth K K Glennon, Suzanne M McDermott

iScience· November 2019

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Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry.
Igor Cestari

J Vis Exp· July 2019

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Nuclear Phosphatidylinositol 5-Phosphatase Is Essential for Allelic Exclusion of Variant Surface Glycoprotein Genes in Trypanosomes.
Igor Cestari, Hilary McLeland-Wieser, Kenneth Stuart

Mol Cell Biol· February 2019

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Inositol polyphosphate multikinase regulation of Trypanosoma brucei life stage development.
Igor Cestari, Atashi Anupama, Kenneth Stuart

Mol Biol Cell· May 2018

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Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes.
Igor Cestari, Ken Stuart

Curr Genomics· February 2018

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Comparative Proteomic Analysis of Lysine Acetylation in Trypanosomes.
Nilmar Silvio Moretti, Igor Cestari, Atashi Anupama, Ken Stuart, Sergio Schenkman

J Proteome Res· January 2018

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Chemogenetic Characterization of Inositol Phosphate Metabolic Pathway Reveals Druggable Enzymes for Targeting Kinetoplastid Parasites.
Igor Cestari, Paige Haas, Nilmar Silvio Moretti, Sergio Schenkman, Ken Stuart

Cell Chem Biol· May 2016

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GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Qiong Li, Christopher Leija, Filipa Rijo-Ferreira, Jun Chen, Igor Cestari

Mol Microbiol· September 2015

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