Publications by authors named "Igor Linhart"

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Carcinogenicity of talc and acrylonitrile.
Leslie T Stayner, Tania Carreón-Valencia, Paul A Demers, Jason M Fritz, Malcolm R Sim, Igor Linhart

Lancet Oncol· August 2024

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New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen.
Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz, Šárka Dušková

Chem Res Toxicol· March 2023

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HPLC-ESI-HRMS2 Determination of N-(2-Hydroxyethyl)-l-valyl-l-leucine in Human Urine: Method Validation.
Iveta Hanzlíková, Jaroslav Mráz, Monika Tvrdíková, Hana Chrástecká, Alena Moulisová, Igor Linhart

J Anal Toxicol· February 2023

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Novel aminoarylcysteine adducts in globin of rats dosed with naphthylamine and nitronaphthalene isomers.
Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz, Šárka Dušková, Monika Tvrdíková

Arch Toxicol· January 2021

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N-(2-Hydroxyethyl)-l-valyl-l-leucine: a novel urinary biomarker of ethylene oxide exposure in humans.
Jaroslav Mráz, Iveta Hanzlíková, Šárka Dušková, Monika Tvrdíková, Igor Linhart

Toxicol Lett· June 2020

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N-(2-Hydroxyethyl)-L-valyl-L-leucine in rat urine as a hydrolytic cleavage product of ethylene oxide adduct with globin.
Jaroslav Mráz, Iveta Hanzlíková, Igor Linhart, Šárka Dušková, Ludmila Dabrowská

Arch Toxicol· March 2019

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Determination of N-(2-hydroxyethyl)valine in globin of ethylene oxide-exposed workers using total acidic hydrolysis and HPLC-ESI-MS.
Jaroslav Mráz, Iveta Hanzlíková, Šárka Dušková, Monika Tvrdíková, Hana Chrástecká, Igor Linhart

Toxicol Lett· December 2018

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Identification of three new phase II metabolites of a designer drug methylone formed in rats by N-demethylation followed by conjugation with dicarboxylic acids.
Monika Židková, Igor Linhart, Marie Balíková, Michal Himl, Veronika Dvořáčková

Xenobiotica· June 2018

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S-(3-Aminobenzanthron-2-yl)cysteine in the globin of rats as a novel type of adduct and possible biomarker of exposure to 3-nitrobenzanthrone, a potent environmental carcinogen.
Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz, Šárka Dušková

Arch Toxicol· October 2017

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Erratum to: S-(3-Aminobenzanthron-2-yl)cysteine in the globin of rats as a novel type of adduct and possible biomarker of exposure to 3-nitrobenzanthrone, a potent environmental carcinogen.
Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz, Šárka Dušková

Arch Toxicol· October 2017

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Study on the metabolism of 5,6-methylenedioxy-2-aminoindane (MDAI) in rats: identification of urinary metabolites.
Monika Židková, Igor Linhart, Marie Balíková, Michal Himl, Lubomír Váňa

Xenobiotica· June 2017

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Biological fate of styrene oxide adducts with globin: Elimination of cleavage products in the rat urine.
Jaroslav Mráz, Iveta Hanzlíková, Šárka Dušková, Ludmila Dabrowská, Hana Chrástecká, Igor Linhart

Toxicol Lett· November 2016

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Radical and Nitrenoid Reactivity of 3-Halo-3-phenyldiazirines.
Rafael Navrátil, Ján Tarábek, Igor Linhart, Tomáš Martinů

Org Lett· August 2016

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Hydrolytic Cleavage Products of Globin Adducts in Urine as Possible Biomarkers of Cumulative Dose: Proof of Concept Using Styrene Oxide as a Model Adduct-Forming Compound.
Jaroslav Mráz, Iveta Hanzlíková, Alena Moulisová, Šárka Dušková, Kamil Hejl, Igor Linhart

Chem Res Toxicol· April 2016

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Metabolic profile of mephedrone: Identification of nor-mephedrone conjugates with dicarboxylic acids as a new type of xenobiotic phase II metabolites.
Igor Linhart, Michal Himl, Monika Židková, Marie Balíková, Eva Lhotková

Toxicol Lett· January 2016

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Identification of new DNA adducts of phenylnitrenium.
Antonín Králík, Igor Linhart, Lubomír Váňa, Alena Moulisová

Chem Res Toxicol· June 2015

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3-(3,4-Dihydroxyphenyl)adenine, a urinary DNA adduct formed in mice exposed to high concentrations of benzene.
Petr Mikeš, Václav Sístek, Jan Krouželka, Antonín Králík, Emil Frantík, Igor Linhart

J Appl Toxicol· June 2013

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Reactions of benzene oxide, a reactive metabolite of benzene, with model nucleophiles and DNA.
Kateřina Míčová, Igor Linhart

Xenobiotica· October 2012

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Vinylphenylmercapturic acids in human urine as biomarkers of styrene ring oxidation.
Igor Linhart, Jaroslav Mráz, Ludmila Dabrowská, Milan Mališ, Jan Krouželka

Toxicol Lett· September 2012

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Carcinogenic 3-nitrobenzanthrone but not 2-nitrobenzanthrone is metabolised to an unusual mercapturic acid in rats.
Igor Linhart, Jaroslav Mráz, Iveta Hanzlíková, Alexandra Silhánková, Emil Frantík

Toxicol Lett· February 2012

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Metabolism of N²-(4-hydroxyphenyl)guanine, a DNA adduct formed from p-benzoquinone, in rat.
Igor Linhart, Petr Mikeš, Antonín Králík, Jaroslav Mráz, Emil Frantík

Toxicol Lett· September 2011

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DNA adducts formed from p-benzoquinone, an electrophilic metabolite of benzene, are extensively metabolized in vivo.
Igor Linhart, Petr Mikes, Emil Frantík, Jaroslav Mráz

Chem Res Toxicol· March 2011

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Urinary N3 adenine DNA adducts in humans occupationally exposed to styrene.
Petr Mikes, Marek Korínek, Igor Linhart, Jan Krouzelka, Ludmila Dabrowská

Toxicol Lett· September 2010

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New urinary metabolites formed from ring-oxidized metabolic intermediates of styrene.
Igor Linhart, Jaroslav Mráz, Jan Scharff, Jan Krouzelka, Sárka Dusková

Chem Res Toxicol· January 2010

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Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene.
Petr Mikes, Marek Korínek, Igor Linhart, Jan Krouzelka, Emil Frantík

Toxicol Lett· January 2009

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