Publications by authors named "Ilaria Tassi"

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The Alzheimer's disease risk genes MS4A4A and MS4A6A cooperate to negatively regulate TREM2 and microglia states.
Dalya Rosner, Jiahong Sun, Rita Cacace, Angie Yee, Chaitanya Wagh, Ilaria Tassi

Neuron· December 2025

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Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease.
Hua Long, Adam Simmons, Arthur Mayorga, Brady Burgess, Tuan Nguyen, Ilaria Tassi

Alzheimers Res Ther· October 2024

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Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report.
Michael T Patterson, Yingzheng Xu, Hannah Hillman, Victoria Osinski, Patricia R Schrank, Ilaria Tassi

Arterioscler Thromb Vasc Biol· July 2024

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TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Francesca Cignarella, Fabia Filipello, Bryan Bollman, Claudia Cantoni, Alberto Locca, Ilaria Tassi

Acta Neuropathol· October 2020

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Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
Shoutang Wang, Meer Mustafa, Carla M Yuede, Santiago Viveros Salazar, Philip Kong, Ilaria Tassi

J Exp Med· September 2020

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Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation.
Estefania Claudio, Ilaria Tassi, Hongshan Wang, Wanhu Tang, Hye-Lin Ha

J Immunol· October 2015

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Adaptive immune-mediated host resistance to Toxoplasma gondii is governed by the NF-κB regulator Bcl-3 in dendritic cells.
Ilaria Tassi, Estefania Claudio, Hongshan Wang, Wanhu Tang, Hye-Lin Ha

Eur J Immunol· July 2015

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The NF-κB regulator Bcl-3 modulates inflammation during contact hypersensitivity reactions in radioresistant cells.
Ilaria Tassi, Nimisha Rikhi, Estefania Claudio, Hongshan Wang, Wanhu Tang

Eur J Immunol· April 2015

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The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity.
Ilaria Tassi, Estefania Claudio, Hongshan Wang, Wanhu Tang, Hye-lin Ha

J Immunol· November 2014

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The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells.
Wanhu Tang, Hongshan Wang, Estefania Claudio, Ilaria Tassi, Hye-lin Ha

Immunity· October 2014

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IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms.
Hye-Lin Ha, Hongshan Wang, Prapaporn Pisitkun, Jin-Chul Kim, Ilaria Tassi

Proc Natl Acad Sci U S A· August 2014

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Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin.
Karel Otero, Isaiah R Turnbull, Pietro Luigi Poliani, William Vermi, Elisa Cerutti, Ilaria Tassi

Nat Immunol· July 2009

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Requirement of phospholipase C-gamma2 (PLCgamma2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization.
Ilaria Tassi, Marina Cella, Iris Castro, Susan Gilfillan, Wasif N Khan

Eur J Immunol· May 2009

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DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo.
Ilaria Tassi, Gaelle Le Friec, Susan Gilfillan, Toshiyuki Takai, Wayne M Yokoyama

Eur J Immunol· April 2009

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NK cell-activating receptors require PKC-theta for sustained signaling, transcriptional activation, and IFN-gamma secretion.
Ilaria Tassi, Marina Cella, Rachel Presti, Angela Colucci, Susan Gilfillan

Blood· November 2008

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Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation.
Laura Piccio, Cecilia Buonsanti, Marina Cella, Ilaria Tassi, Robert E Schmidt

Brain· November 2008

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Increased frequency of human leukocyte antigen-E inhibitory receptor CD94/NKG2A-expressing peritoneal natural killer cells in patients with endometriosis.
Ricciarda Galandrini, Maria Grazia Porpora, Antonella Stoppacciaro, Federica Micucci, Cristina Capuano, Ilaria Tassi

Fertil Steril· May 2008

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p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells.
Ilaria Tassi, Marina Cella, Susan Gilfillan, Isaiah Turnbull, Thomas G Diacovo

Immunity· August 2007

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FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.
Timothy J Wilson, Rachel M Presti, Ilaria Tassi, Edgar T Overton, Marina Cella

Blood· May 2007

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Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse.
Ilaria Tassi, Julia Klesney-Tait, Marco Colonna

Immunol Rev· December 2006

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The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells.
Ilaria Tassi, Marco Colonna

J Immunol· December 2005

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Arf6: a new player in FcgammaRIIIA lymphocyte-mediated cytotoxicity.
Ricciarda Galandrini, Federica Micucci, Ilaria Tassi, Maria Grazia Cifone, Benedetta Cinque

Blood· July 2005

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Phospholipase C-gamma 2 is a critical signaling mediator for murine NK cell activating receptors.
Ilaria Tassi, Rachel Presti, Sungjin Kim, Wayne M Yokoyama, Susan Gilfillan

J Immunol· July 2005

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Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.
Marina Cella, Keiko Fujikawa, Ilaria Tassi, Sunjin Kim, Kevin Latinis

J Exp Med· September 2004

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SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells.
Ricciarda Galandrini, Ilaria Tassi, Gianfranco Mattia, Luisa Lenti, Mario Piccoli

Blood· December 2002

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