Publications by authors named "Imre Timea"

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Target Agnostic Photoaffinity Labelling by Sulfonylhydrazones.
Kristóf Garami, Nikolett Péczka, László Petri, Tímea Imre, Tamás Langó

Angew Chem Int Ed Engl· April 2025

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Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents.
Levente Kollár, Katarina Grabrijan, Martina Hrast Rambaher, Krištof Bozovičar, Tímea Imre

J Enzyme Inhib Med Chem· December 2024

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Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a precision-guided warhead scaffold.
Ádám Levente Póti, Dániel Bálint, Anita Alexa, Péter Sok, Kristóf Ozsváth

Nat Commun· October 2024

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Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads.
Dániel Bálint, Ádám Levente Póti, Anita Alexa, Péter Sok, Krisztián Albert

Nat Commun· October 2024

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Site-Selective Antibody Conjugation with Dibromopyrazines.
Dénes Szepesi Kovács, Bettina Pásztor, Péter Ábrányi-Balogh, László Petri, Tímea Imre

Bioconjug Chem· September 2024

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Mapping protein binding sites by photoreactive fragment pharmacophores.
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri

Commun Chem· July 2024

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Molecular Mechanism of Labelling Functional Cysteines by Heterocyclic Thiones.
Levente M Mihalovits, Levente Kollár, Dávid Bajusz, Damijan Knez, Krištof Bozovičar

Chemphyschem· January 2024

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Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch

J Med Chem· January 2024

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Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4).
Márk Kozsurek, Kornél Király, Klára Gyimesi, Erika Lukácsi, Csaba Fekete

Int J Mol Sci· January 2023

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Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead.
Katarina Grabrijan, Martina Hrast, Matic Proj, Ana Dolšak, Irena Zdovc

Eur J Med Chem· December 2022

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Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors.
Péter Ábrányi-Balogh, Aaron Keeley, György G Ferenczy, László Petri, Tímea Imre

Pharmaceuticals (Basel)· November 2022

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A covalent strategy to target intrinsically disordered proteins: Discovery of novel tau aggregation inhibitors.
László Petri, Péter Ábrányi-Balogh, Darius Vagrys, Tímea Imre, Nikolett Varró

Eur J Med Chem· March 2022

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Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads.
Levente Kollár, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez

Cells· December 2021

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Discovery of selective fragment-sized immunoproteasome inhibitors.
Levente Kollár, Martina Gobec, Bence Szilágyi, Matic Proj, Damijan Knez

Eur J Med Chem· July 2021

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Age-Related Inflammatory Balance Shift, Nasal Barrier Function, and Cerebro-Morphological Status in Healthy and Diseased Rodents.
Zsófia Varga-Medveczky, Noémi Kovács, Melinda E Tóth, Miklós Sántha, Ildikó Horváth, Timea Imre

Front Neurosci· July 2021

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Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
László Petri, Péter Ábrányi-Balogh, Imre Tímea, Gyula Pálfy, András Perczel

Chembiochem· February 2021

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WIDOCK: a reactive docking protocol for virtual screening of covalent inhibitors.
Andrea Scarpino, László Petri, Damijan Knez, Tímea Imre, Péter Ábrányi-Balogh

J Comput Aided Mol Des· February 2021

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An electrophilic warhead library for mapping the reactivity and accessibility of tractable cysteines in protein kinases.
László Petri, Attila Egyed, Dávid Bajusz, Tímea Imre, Anasztázia Hetényi

Eur J Med Chem· December 2020

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Bromo-Cyclobutenaminones as New Covalent UDP--Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors.
David J Hamilton, Péter Ábrányi-Balogh, Aaron Keeley, László Petri, Martina Hrast

Pharmaceuticals (Basel)· November 2020

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Corrigendum to "DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits". Neurobiology of Disease 134 (2020) 104629.
Katalin Solti, Wei-Li Kuan, Balázs Fórizs, Gergely Kustos, Judith Mihály

Neurobiol Dis· August 2020

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Verification of P-Glycoprotein Function at the Dermal Barrier in Diffusion Cells and Dynamic "Skin-On-A-Chip" Microfluidic Device.
Ágnes Bajza, Dorottya Kocsis, Orsolya Berezvai, András József Laki, Bence Lukács

Pharmaceutics· August 2020

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Modulation of nose-to-brain delivery of a P-glycoprotein (MDR1) substrate model drug (quinidine) in rats.
Luca Anna Bors, Ágnes Bajza, Míra Mándoki, Benedek József Tasi, György Cserey

Brain Res Bull· July 2020

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Comparative reactivity analysis of small-molecule thiol surrogates.
László Petri, Péter Ábrányi-Balogh, Petra Regina Varga, Tímea Imre, György Miklós Keserű

Bioorg Med Chem· April 2020

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Cysteine specific bioconjugation with benzyl isothiocyanates.
László Petri, Péter A Szijj, Ádám Kelemen, Tímea Imre, Ágnes Gömöry

RSC Adv· April 2020

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DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits.
Katalin Solti, Wei-Li Kuan, Balázs Fórizs, Gergely Kustos, Judith Mihály

Neurobiol Dis· February 2020

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