Publications by authors named "In-Youb Chang"

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SLX1 Inhibition Enhances Olaparib Sensitivity by Impairing Homologous Recombination Repair in Breast Cancer.
Jin-Young Kim, Jeeho Kim, In-Youb Chang, Sang-Gon Park, Ho Jin You

Int J Mol Sci· November 2025

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The role of Ephexin1 in translation and mTOR-targeted cancer therapy.
Jeeho Kim, In-Youb Chang, Jung-Hee Lee, Jeongsik Yong, Young Jin Jeon

Exp Mol Med· August 2025

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The feasible role of soluble E‑cadherin in spheroidogenesis of HCT116 colorectal cancer cells, a candidate biomarker for liquid biopsy.
In-Youb Chang, Hye-Jin Boo, Jin Won Hyun, Sang-Pil Yoon

Oncol Lett· May 2025

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Chitosan oligosaccharide enhances the anti-cancer effects of 5-fluorouracil on SNU-C5 colorectal cancer cells by activating ERK.
Ji-Su Han, Hye-Jin Boo, Jin Won Hyun, Heesang Song, In-Youb Chang

Oncol Res· May 2025

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Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation.
Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

Exp Mol Med· February 2025

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Increased soluble E‑cadherin of spheroid formation supplemented with fetal bovine serum in colorectal cancer cells.
In-Youb Chang, Sang-Pil Yoon

Oncol Lett· May 2023

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SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination.
Seo-Yeon Jeong, Gurusamy Hariharasudhan, Min-Ji Kim, Ji-Yeon Lim, Sung Mi Jung, In-Youb Chang

Nucleic Acids Res· October 2022

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Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1.
Jeeho Kim, In-Youb Chang, Ho Jin You

Cell Death Dis· June 2022

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HspBP1 is a dual function regulatory protein that controls both DNA repair and apoptosis in breast cancer cells.
Cha Kyung Youn, Jung-Hee Lee, Gurusamy Hariharasudhan, Hong Beum Kim, Jeeho Kim, In-Youb Chang

Cell Death Dis· April 2022

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TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair.
Gurusamy Hariharasudhan, Seo-Yeon Jeong, Min-Ji Kim, Sung Mi Jung, Gwanwoo Seo, In-Youb Chang

Nucleic Acids Res· February 2022

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Akt-mediated Ephexin1-Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation.
Jeeho Kim, Young Jin Jeon, Sung-Chul Lim, Joohyun Ryu, Jung-Hee Lee, In-Youb Chang

Cell Death Dis· October 2021

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Oncogenic Ras downregulates expression through generation of reactive oxygen species.
Semo Jun, Seok Won Kim, Byeol Kim, In-Youb Chang, Seon-Joo Park

Korean J Physiol Pharmacol· May 2020

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Karyopherin α-2 Mediates MDC1 Nuclear Import through a Functional Nuclear Localization Signal in the tBRCT Domain of MDC1.
Kamalakannan Radhakrishnan, Seon-Joo Park, Seok Won Kim, Gurusamy Hariharasudhan, Seo-Yeon Jeong, In Youb Chang

Int J Mol Sci· April 2020

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Author Correction: ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability.
Jung-Hee Lee, Seon-Joo Park, Gurusamy Hariharasudhan, Min-Ji Kim, Sung Mi Jung, In-Youb Chang

Nat Commun· June 2018

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ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability.
Jung-Hee Lee, Seon-Joo Park, Gurusamy Hariharasudhan, Min-Ji Kim, Sung Mi Jung, In-Youb Chang

Nat Commun· October 2017

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Morphological effects of mitomycin C on urothelial responses to experimentally-induced urethral stricture in rats.
In Youb Chang, Jin Nam Kim, Sun-Ouck Kim, Misook Han, Jung-Sik Huh

Int J Urol· July 2015

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MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1.
Jung-Hee Lee, Seon-Joo Park, Seo-Yeon Jeong, Min-Ji Kim, Semo Jun, In-Youb Chang

Cancer Res· April 2015

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Apurinic/apyrimidinic endonuclease 1 on aging-associated deteriorations in rat kidneys.
In Youb Chang, Jung-Hee Lee, Jin Nam Kim, Kun Ho Lee, Kyung Soo Park

Free Radic Res· January 2015

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A comparison of the steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing 6 on the brain and testes between young and aged rats.
In Youb Chang, Takbum Ohn, Young Jin Jeon, Kun Ho Lee, Jung Woo Kim

Acta Histochem· May 2014

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Apurinic/apyrimidinic endonuclease 1, the sensitive marker for DNA deterioration in dextran sulfate sodium-induced acute colitis.
In-Youb Chang, Jin Nam Kim, Young Hee Maeng, Sang Pil Yoon

Redox Rep· April 2014

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Colon cancer progression is driven by APEX1-mediated upregulation of Jagged.
Mi-Hwa Kim, Hong-Beum Kim, Sang Pil Yoon, Sung-Chul Lim, Man Jin Cha, In-Youb Chang

J Clin Invest· July 2013

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Acute responses of DNA repair proteins and StarD6 in rat hippocampus after domoic acid-induced excitotoxicity.
In Youb Chang, Jin Ho Kim, Kyung Won Cho, Sang Pil Yoon

Acta Histochem· April 2013

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A role of DNA-dependent protein kinase for the activation of AMP-activated protein kinase in response to glucose deprivation.
Parmeshwar Narayan Amatya, Hong-Beum Kim, Seon-Joo Park, Cha-Kyung Youn, Jin-Won Hyun, In-Youb Chang

Biochim Biophys Acta· December 2012

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Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine.
Byung Joo Kim, In Youb Chang, Insuk So

Cell Physiol Biochem· November 2012

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MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2.
Chunmei Piao, Cha-Kyung Youn, Min Jin, Sang Pil Yoon, In-Youb Chang

Cell Cycle· September 2012

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