Publications by authors named "Ina Nepstad"

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Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.
Ina Nepstad, Kimberley Joanne Hatfield, Ida Sofie Grønningsæter, Elise Aasebø, Maria Hernandez-Valladares

Signal Transduct Target Ther· February 2021

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The PI3K-Akt-mTOR Signaling Pathway in Human Acute Myeloid Leukemia (AML) Cells.
Ina Nepstad, Kimberley Joanne Hatfield, Ida Sofie Grønningsæter, Håkon Reikvam

Int J Mol Sci· April 2020

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Clonal Heterogeneity Reflected by PI3K-AKT-mTOR Signaling in Human Acute Myeloid Leukemia Cells and Its Association with Adverse Prognosis.
Ina Nepstad, Kimberley Joanne Hatfield, Tor Henrik Anderson Tvedt, Håkon Reikvam, Øystein Bruserud

Cancers (Basel)· September 2018

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Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic, and transcriptomic comparison.
Ina Nepstad, Kimberley J Hatfield, Elise Aasebø, Maria Hernandez-Valladares, Annette K Brenner

Expert Opin Ther Targets· July 2018

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Cytokines, Adhesion Molecules, and Matrix Metalloproteases as Predisposing, Diagnostic, and Prognostic Factors in Venous Thrombosis.
Knut A Mosevoll, Silje Johansen, Øystein Wendelbo, Ina Nepstad, Øystein Bruserud

Front Med (Lausanne)· May 2018

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Resistance to the Antiproliferative In Vitro Effect of PI3K-Akt-mTOR Inhibition in Primary Human Acute Myeloid Leukemia Cells Is Associated with Altered Cell Metabolism.
Ina Nepstad, Håkon Reikvam, Annette K Brenner, Øystein Bruserud, Kimberley J Hatfield

Int J Mol Sci· January 2018

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Patients with acute myeloid leukemia can be subclassified based on the constitutive cytokine release of the leukemic cells; the possible clinical relevance and the importance of cellular iron metabolism.
Annette K Brenner, Tor Henrik Anderson Tvedt, Ina Nepstad, Kristin P Rye, Karen M Hagen

Expert Opin Ther Targets· April 2017

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Antileukemic effects of midostaurin in acute myeloid leukemia - the possible importance of multikinase inhibition in leukemic as well as nonleukemic stromal cells.
Tor Henrik Tvedt, Ina Nepstad, Øystein Bruserud

Expert Opin Investig Drugs· March 2017

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Mesenchymal Stem Cells Support Survival and Proliferation of Primary Human Acute Myeloid Leukemia Cells through Heterogeneous Molecular Mechanisms.
Annette K Brenner, Ina Nepstad, Øystein Bruserud

Front Immunol· February 2017

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Correction: Pharmacologic targeting of the PI3K/mTOR pathway controls release of angioregulators from primary human acute myeloid leukemia cells and their neighboring stromal cells.
Håkon Reikvam, Ina Nepstad, Øystein Bruserud, Kimberley Joanne Hatfield

Oncotarget· January 2017

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Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia.
Pierre Sujobert, Laury Poulain, Etienne Paubelle, Florence Zylbersztejn, Adrien Grenier, Ina Nepstad

Cell Rep· June 2015

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Connexin expression in human acute myeloid leukemia cells: identification of patient subsets based on protein and global gene expression profiles.
Håkon Reikvam, Anita Ryningen, Lars Rune Sæterdal, Ina Nepstad, Brynjar Foss

Int J Mol Med· March 2015

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STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia.
Øystein Bruserud, Ina Nepstad, Michelle Hauge, Kimberley Joanne Hatfield, Håkon Reikvam

Expert Rev Hematol· February 2015

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Heat shock protein 70 - the next chaperone to target in the treatment of human acute myelogenous leukemia?
Håkon Reikvam, Annette K Brenner, Ina Nepstad, André Sulen, Øystein Bruserud

Expert Opin Ther Targets· August 2014

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Comparison of in vitro responses to fresh whole blood and reconstituted whole blood after collagen stimulation.
Ina Nepstad, Håkon Reikvam, Geir Strandenes, John R Hess, Torunn O Apelseth

Blood Transfus· January 2014

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Predicting effects of kinase inhibitor in therapy for myeloid malignancies - the challenges in capturing disease heterogeneity.
Håkon Reikvam, Ina Nepstad, Jerome Tamburini

Expert Opin Investig Drugs· November 2013

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The angioregulatory cytokine network in human acute myeloid leukemia - from leukemogenesis via remission induction to stem cell transplantation.
Håkon Reikvam, Kimberley Joanne Hatfield, Hanne Fredly, Ina Nepstad, Knut Anders Mosevoll

Eur Cytokine Netw· July 2013

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Pharmacological targeting of the PI3K/mTOR pathway alters the release of angioregulatory mediators both from primary human acute myeloid leukemia cells and their neighboring stromal cells.
Håkon Reikvam, Ina Nepstad, Øystein Bruserud, Kimberley Joanne Hatfield

Oncotarget· June 2013

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Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors.
Håkon Reikvam, Ina Nepstad, André Sulen, Bjørn Tore Gjertsen, Kimberley Joanne Hatfield

Expert Opin Investig Drugs· May 2013

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The effects of selective serotonin reuptake inhibitors on platelet function in whole blood and platelet concentrates.
Anne-Grete Reikvam, Steinar Hustad, Håkon Reikvam, Torunn Oveland Apelseth, Ina Nepstad

Platelets· November 2012

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Inhibition of Mammalian target of rapamycin in human acute myeloid leukemia cells has diverse effects that depend on the environmental in vitro stress.
Anita Ryningen, Håkon Reikvam, Ina Nepstad, Kristin Paulsen Rye, Oystein Bruserud

Bone Marrow Res· October 2012

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Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?
Galina Tsykunova, Håkon Reikvam, Aymen Bushra Ahmed, Ina Nepstad, Bjørn Tore Gjertsen

Expert Opin Investig Drugs· May 2012

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Characterisation and expression analysis of the Atlantic halibut (Hippoglossus hippoglossus L.) cytokines: IL-1β, IL-6, IL-11, IL-12β and IFNγ.
Aina-Cathrine Øvergård, Ina Nepstad, Audun Helge Nerland, Sonal Patel

Mol Biol Rep· March 2012

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