Publications by authors named "Inga Hoffmann"

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Transcriptome Analysis of Matched Cohorts of Long- and Short-term Survivors in Advanced High-grade Serous Tubo-ovarian Cancer.
Sofya Marchenko, Niklas Goernitz, Wiebke A Zoern, Maria Joosten, Inga Hoffmann

Clin Cancer Res· September 2025

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AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.
Nanna Monjé, Mihnea P Dragomir, Bruno V Sinn, Inga Hoffmann, Anuar Makhmut

Br J Cancer· May 2024

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LRP1B-a prognostic marker in tubo-ovarian high-grade serous carcinoma.
Svenja Kolb, Inga Hoffmann, Nanna Monjé, Mihnea P Dragomir, Paul Jank

Hum Pathol· November 2023

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Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer.
Inga Hoffmann, Mihnea P Dragomir, Nanna Monjé, Carlotta Keunecke, Catarina Alisa Kunze

Neoplasia· October 2023

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High EVI1 and PARP1 expression as favourable prognostic markers in high-grade serous ovarian carcinoma.
Paul Jank, Jonas Leichsenring, Svenja Kolb, Inga Hoffmann, Philip Bischoff

J Ovarian Res· July 2023

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Prognostic value of regulatory T cells and T helper 17 cells in high grade serous ovarian carcinoma.
Sofya Marchenko, Iris Piwonski, Inga Hoffmann, Bruno Valentin Sinn, Catarina Alisa Kunze

J Cancer Res Clin Oncol· June 2023

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Proficiency testing of PIK3CA mutations in HR+/HER2-breast cancer on liquid biopsy and tissue.
Claudia Vollbrecht, Inga Hoffmann, Annika Lehmann, Sabine Merkelbach-Bruse, Jana Fassunke

Virchows Arch· April 2023

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DNA methylation-based classification of sinonasal tumors.
Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Inga Hoffmann

Nat Commun· November 2022

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Low Expression of RGS2 Promotes Poor Prognosis in High-Grade Serous Ovarian Cancer.
Jana Ihlow, Nanna Monjé, Inga Hoffmann, Philip Bischoff, Bruno Valentin Sinn

Cancers (Basel)· September 2022

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Mucosal melanomas of different anatomic sites share a common global DNA methylation profile with cutaneous melanoma but show location-dependent patterns of genetic and epigenetic alterations.
Philipp Jurmeister, Niklas Wrede, Inga Hoffmann, Claudia Vollbrecht, Daniel Heim

J Pathol· January 2022

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Comparative investigation of cell cycle and immunomodulatory genes in mucosal and cutaneous melanomas: Preliminary data suggest a potential promising clinical role for p16 and the PD-1/PD-L1 axis.
Niklas Wrede, Inga Hoffmann, Claudia Vollbrecht, Ines Koch, Peggy Wolkenstein

Pathol Res Pract· January 2022

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The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.
Martin Roatsch, Inga Hoffmann, Martine I Abboud, Rebecca L Hancock, Hanna Tarhonskaya

ACS Chem Biol· August 2019

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Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases.
Martin Roatsch, Dina Robaa, Martin Pippel, Joanne E Nettleship, Yamini Reddivari, Inga Hoffmann

Future Med Chem· September 2016

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4-Biphenylalanine- and 3-Phenyltyrosine-Derived Hydroxamic Acids as Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A.
Ludovica Morera, Martin Roatsch, Michael C D Fürst, Inga Hoffmann, Johanna Senger

ChemMedChem· September 2016

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Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide.
Linda Sooman, Anneli Wennman, Mats Hamberg, Inga Hoffmann, Ernst H Oliw

Biochim Biophys Acta· February 2016

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Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes.
Inga Hoffmann, Fredrik Jernerén, Ernst H Oliw

J Lipid Res· October 2014

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Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum.
Inga Hoffmann, Ernst H Oliw

J Lipid Res· December 2013

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7,8- and 5,8-Linoleate diol synthases support the heterolytic scission of oxygen-oxygen bonds by different amide residues.
Inga Hoffmann, Ernst H Oliw

Arch Biochem Biophys· November 2013

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Expression of fusion proteins of Aspergillus terreus reveals a novel allene oxide synthase.
Inga Hoffmann, Fredrik Jernerén, Ernst H Oliw

J Biol Chem· April 2013

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The role of histone demethylases in cancer therapy.
Inga Hoffmann, Martin Roatsch, Martin L Schmitt, Luca Carlino, Martin Pippel

Mol Oncol· December 2012

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Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs.
Inga Hoffmann, Mats Hamberg, Roland Lindh, Ernst H Oliw

Biochim Biophys Acta· December 2012

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Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases.
Ernst H Oliw, Anneli Wennman, Inga Hoffmann, Ulrike Garscha, Mats Hamberg

J Lipid Res· November 2011

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Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms.
Ernst H Oliw, Fredrik Jernerén, Inga Hoffmann, Margareta Sahlin, Ulrike Garscha

Biochim Biophys Acta· March 2011

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Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain. A comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase.
Inga Hoffmann, Fredrik Jernerén, Ulrike Garscha, Ernst H Oliw

Arch Biochem Biophys· February 2011

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Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus.
Fredrik Jernerén, Ulrike Garscha, Inga Hoffmann, Mats Hamberg, Ernst H Oliw

Biochim Biophys Acta· April 2010

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