Publications by authors named "Inge de Graaf"

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Setting goals for agricultural nitrogen emission reduction to ensure safe air and groundwater quality: A case study of Quzhou, the North China Plain.
Fanlei Meng, Reinder Ronda, Maryna Strokal, Carolien Kroeze, Lin Ma, Inge de Graaf

J Environ Manage· February 2024

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Unraveling Hematotoxicity of α-Amanitin in Cultured Hematopoietic Cells.
Willemien F J Hof, Miranda Visser, Joyce J de Jong, Marian N Rajasekar, Jan Jacob Schuringa, Inge A M de Graaf

Toxins (Basel)· January 2024

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Multicompartment Depletion Factors for Water Consumption on a Global Scale.
Eleonore Pierrat, Martin Dorber, Inge de Graaf, Alexis Laurent, Michael Z Hauschild

Environ Sci Technol· March 2023

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Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits.
Natalia Estrada-Ortiz, Viktoriia Starokozhko, Hidde van Steenwijk, Cor van der Heide, Hjalmar Permentier, Inge Anne Maria de Graaf

J Appl Toxicol· December 2022

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Rifampicin Induces Gene, Protein, and Activity of P-Glycoprotein (ABCB1) in Human Precision-Cut Intestinal Slices.
Ondrej Martinec, Carin Biel, Inge A M de Graaf, Martin Huliciak, Koert P de Jong

Front Pharmacol· June 2021

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Prenatal smoke exposure induces persistent methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring.
Khosbayar Lkhagvadorj, Karolin F Meyer, Laura P Verweij, Wierd Kooistra, Marjan Reinders-Luinge, Inge A M de Graaf

Epigenetics· December 2020

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Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Methylation.
Khosbayar Lkhagvadorj, Zhijun Zeng, Karolin F Meyer, Laura P Verweij, Wierd Kooistra, Inge A M de Graaf

Int J Mol Sci· December 2020

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Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells.
Leanne Ambrosio, Monica Argenziano, Marie Angèle Cucci, Margherita Grattarola, Inge A M de Graaf

Antioxidants (Basel)· October 2020

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Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin: Evaluation of toxicity and transport mechanisms in the liver.
Martina Daga, Inge A M de Graaf, Monica Argenziano, Ana Sofia Martinez Barranco, Maximillian Loeck

Toxicol In Vitro· June 2020

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toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands.
Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A M de Graaf

Toxicol Res (Camb)· November 2019

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Environmental flow limits to global groundwater pumping.
Inge E M de Graaf, Tom Gleeson, L P H Rens van Beek, Edwin H Sutanudjaja, Marc F P Bierkens

Nature· October 2019

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Growth factors of stem cell niche extend the life-span of precision-cut intestinal slices in culture: A proof-of-concept study.
Emilia Bigaeva, Jordy J M Bomers, Carin Biel, Henricus A M Mutsaers, Inge A M de Graaf

Toxicol In Vitro· September 2019

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Human and rat precision-cut intestinal slices as ex vivo models to study bile acid uptake by the apical sodium-dependent bile acid transporter.
Ming Li, Ivan Vokral, Bernard Evers, Inge A M de Graaf, Marina H de Jager

Eur J Pharm Sci· August 2018

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On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent.
Sarah Spreckelmeyer, Natalia Estrada-Ortiz, Gerian G H Prins, Margot van der Zee, Bente Gammelgaard, Inge A M de Graaf

Metallomics· December 2017

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Rat precision-cut liver slices predict drug-induced cholestatic injury.
Viktoriia Starokozhko, Rick Greupink, Petra van de Broek, Nashwa Soliman, Samiksha Ghimire, Inge A M de Graaf

Arch Toxicol· October 2017

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Anticancer Gold N-Heterocyclic Carbene Complexes: A Comparative in vitro and ex vivo Study.
Natalia Estrada-Ortiz, Federica Guarra, Inge A M de Graaf, Lorella Marchetti, Marina H de Jager

ChemMedChem· September 2017

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The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
Ming Li, Inge A M de Graaf, Evita van de Steeg, Marina H de Jager, Geny M M Groothuis

Toxicol In Vitro· April 2017

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P-gp activity and inhibition in the different regions of human intestine ex vivo.
Ming Li, Inge A M de Graaf, Marina H de Jager, Geny M M Groothuis

Biopharm Drug Dispos· March 2017

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Precision-cut intestinal slices: alternative model for drug transport, metabolism, and toxicology research.
Ming Li, Inge A M de Graaf, Geny M M Groothuis

Expert Opin Drug Metab Toxicol· September 2016

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An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures.
George J Dugbartey, Luke J Peppone, Inge A M de Graaf

Toxicology· September 2016

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Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin.
Jill Moser, Peter Heeringa, Rianne M Jongman, Peter J Zwiers, Anita E Niemarkt, Inge A de Graaf

J Immunol· June 2016

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The Consequence of Drug-Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices.
Ming Li, Inge A M de Graaf, Sanna Siissalo, Marina H de Jager, Annie van Dam

Drug Metab Dispos· May 2016

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Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
Ming Li, Inge A M de Graaf, Marina H de Jager, Geny M M Groothuis

Toxicol In Vitro· August 2015

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Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group.
Julienne K Muenzner, Tobias Rehm, Bernhard Biersack, Angela Casini, Inge A M de Graaf

J Med Chem· August 2015

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Precision-cut rat, mouse, and human intestinal slices as novel models for the early-onset of intestinal fibrosis.
Bao Tung Pham, Wouter Tobias van Haaften, Dorenda Oosterhuis, Judith Nieken, Inge Anne Maria de Graaf

Physiol Rep· April 2015

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