Publications by authors named "Ingolf Lachmann"

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Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer's disease.
Barbara Morgado, Hans-Wolfgang Klafki, Chris Bauer, Katharina Waniek, Hermann Esselmann, Ingolf Lachmann

Eur Arch Psychiatry Clin Neurosci· December 2025

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Evaluation of a fully automated assay for the measurement of plasma pTau217 and a composite score integrating the ratio Aβ1-42/1-40 as biomarkers of Alzheimer's disease.
Barbara Morgado, Hans-Wolfgang Klafki, Chris Bauer, Annik Steiert, Katharina Waniek, Ingolf Lachmann

Eur Arch Psychiatry Clin Neurosci· September 2025

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Letter to the Editor: The WHO HDV RNA international standard does not reflect variability of real-world samples.
Lisa Sandmann, Birgit Bremer, Katja Deterding, Kerstin Port, Beatrix Gey, Ingolf Lachmann

Hepatology· February 2025

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Alzheimer and Parkinson diseases, frontotemporal lobar degeneration and amyotrophic lateral sclerosis overlapping neuropathology start in the first two decades of life in pollution exposed urbanites and brain ultrafine particulate matter and industrial nanoparticles, including Fe, Ti, Al, V, Ni, Hg, Co, Cu, Zn, Ag, Pt, Ce, La, Pr and W are key players. Metropolitan Mexico City health crisis is in progress.
Lilian Calderón-Garcidueñas, Elijah W Stommel, Ricardo Torres-Jardón, Jacqueline Hernández-Luna, Mario Aiello-Mora, Ingolf Lachmann

Front Hum Neurosci· January 2024

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Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD.
Stefanie Lerche, Milan Zimmermann, Benjamin Roeben, Isabel Wurster, Franca Laura Fries, Ingolf Lachmann

NPJ Parkinsons Dis· March 2023

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Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation.
Hans-W Klafki, Jonathan Vogelgsang, Ekaterina Manuilova, Chris Bauer, Alexander Jethwa, Ingolf Lachmann

Alzheimers Res Ther· September 2022

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Linking the phenotype of SNCA Triplication with PET-MRI imaging pattern and alpha-synuclein CSF seeding.
Isabel Wurster, Corinne Quadalti, Marcello Rossi, Ann-Kathrin Hauser, Christian Deuschle, Ingolf Lachmann

NPJ Parkinsons Dis· September 2022

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TDP-43 CSF Concentrations Increase Exponentially with Age in Metropolitan Mexico City Young Urbanites Highly Exposed to PM and Ultrafine Particles and Historically Showing Alzheimer and Parkinson's Hallmarks. Brain TDP-43 Pathology in MMC Residents Is Associated with High Cisternal CSF TDP-43 Concentrations.
Lilian Calderón-Garcidueñas, Elijah W Stommel, Ingolf Lachmann, Katharina Waniek, Chih-Kai Chao

Toxics· September 2022

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CSF and Serum Levels of Inflammatory Markers in PD: Sparse Correlation, Sex Differences and Association With Neurodegenerative Biomarkers.
Stefanie Lerche, Milan Zimmermann, Isabel Wurster, Benjamin Roeben, Franca Laura Fries, Ingolf Lachmann

Front Neurol· February 2022

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CSF Protein Level of Neurotransmitter Secretion, Synaptic Plasticity, and Autophagy in PD and DLB.
Stefanie Lerche, Simon Sjödin, Ann Brinkmalm, Kaj Blennow, Isabel Wurster, Ingolf Lachmann

Mov Disord· November 2021

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Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson's disease and dementia with Lewy bodies.
Kathrin Brockmann, Corinne Quadalti, Stefanie Lerche, Marcello Rossi, Isabel Wurster, Ingolf Lachmann

Acta Neuropathol Commun· October 2021

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Aggrecan modulates the expression and phosphorylation of tau in a novel bigenic TauP301L - Acan mouse model.
Sophie Schmidt, Caroline Stapf, Sandra Schmutzler, Ingolf Lachmann, Thomas Arendt

Eur J Neurosci· June 2021

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The Mutation Matters: CSF Profiles of GCase, Sphingolipids, α-Synuclein in PD.
Stefanie Lerche, Claudia Schulte, Isabel Wurster, Gerrit Machetanz, Benjamin Roeben, Ingolf Lachmann

Mov Disord· May 2021

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Quadruple abnormal protein aggregates in brainstem pathology and exogenous metal-rich magnetic nanoparticles (and engineered Ti-rich nanorods). The substantia nigrae is a very early target in young urbanites and the gastrointestinal tract a key brainstem portal.
Lilian Calderón-Garcidueñas, Angélica González-Maciel, Rafael Reynoso-Robles, Jessica Hammond, Randy Kulesza, Ingolf Lachmann

Environ Res· December 2020

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Development and Technical Validation of an Immunoassay for the Detection of APP (Aβ) in Biological Samples.
Hans W Klafki, Petra Rieper, Anja Matzen, Silvia Zampar, Oliver Wirths, Ingolf Lachmann

Int J Mol Sci· September 2020

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Differential diagnostic value of total alpha-synuclein assay in the cerebrospinal fluid between Alzheimer's disease and dementia with Lewy bodies from the prodromal stage.
Olivier Bousiges, Nathalie Philippi, Thomas Lavaux, Armand Perret-Liaudet, Ingolf Lachmann

Alzheimers Res Ther· September 2020

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Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease.
Sonia M Vallabh, Eric Vallabh Minikel, Victoria J Williams, Becky C Carlyle, Alison J McManus, Ingolf Lachmann

BMC Med· June 2020

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Parkinson's Disease: Glucocerebrosidase 1 Mutation Severity Is Associated with CSF Alpha-Synuclein Profiles.
Stefanie Lerche, Isabel Wurster, Benjamin Roeben, Milan Zimmermann, Benjamin Riebenbauer, Ingolf Lachmann

Mov Disord· March 2020

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Cerebrospinal fluid non-phosphorylated tau in the differential diagnosis of Creutzfeldt-Jakob disease: a comparative prospective study with 14-3-3.
Franc Llorens, Anna Villar-Piqué, Peter Hermann, Matthias Schmitz, Stefan Goebel, Ingolf Lachmann

J Neurol· February 2020

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Non-Phosphorylated Tau in Cerebrospinal Fluid is a Marker of Alzheimer's Disease Continuum in Young Urbanites Exposed to Air Pollution.
Lilian Calderón-Garcidueñas, Partha S Mukherjee, Katharina Waniek, Max Holzer, Chih-Kai Chao, Ingolf Lachmann

J Alzheimers Dis· November 2019

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Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.
Stefanie Lerche, Gerrit Machetanz, Isabel Wurster, Benjamin Roeben, Milan Zimmermann, Ingolf Lachmann

Mov Disord· July 2019

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Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases.
Anna Villar-Piqué, Matthias Schmitz, Ingolf Lachmann, André Karch, Olga Calero

Mol Neurobiol· April 2019

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Evaluation of cerebrospinal fluid proteins as potential biomarkers for early stage Parkinson's disease diagnosis.
Marcia Cristina T Dos Santos, Dieter Scheller, Claudia Schulte, Irene R Mesa, Peter Colman, Ingolf Lachmann

PLoS One· April 2019

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Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease.
Joana R F Santos, Chris Bauer, Johannes Schuchhardt, Dirk Wedekind, Katharina Waniek, Ingolf Lachmann

J Neural Transm (Vienna)· March 2019

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Cerebrospinal Fluid Prion Disease Biomarkers in Pre-clinical and Clinical Naturally Occurring Scrapie.
Franc Llorens, Tomás Barrio, Ângela Correia, Anna Villar-Piqué, Katrin Thüne, Ingolf Lachmann

Mol Neurobiol· November 2018

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