Publications by authors named "Ingrid Deckman"

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Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
Robert H Scannevin, Richard Alexander, Tara Mezzasalma Haarlander, Sharon L Burke, Monica Singer, Ingrid Deckman

J Biol Chem· October 2017

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Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution.
Céline Schalk-Hihi, Carsten Schubert, Richard Alexander, Shariff Bayoumy, Jose C Clemente, Ingrid Deckman

Protein Sci· April 2011

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A novel fluorogenic substrate for the measurement of endothelial lipase activity.
Andrew L Darrow, Matthew W Olson, Hong Xin, Sharon L Burke, Charles Smith, Ingrid C Deckman

J Lipid Res· February 2011

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Potency variation of small-molecule chymase inhibitors across species.
Jukka Kervinen, Carl Crysler, Shariff Bayoumy, Marta C Abad, John Spurlino, Ingrid Deckman

Biochem Pharmacol· October 2010

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Structural basis for elastolytic substrate specificity in rodent alpha-chymases.
Jukka Kervinen, Marta Abad, Carl Crysler, Michael Kolpak, Andrew D Mahan, Ingrid Deckman

J Biol Chem· January 2008

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Enhancing recombinant protein quality and yield by protein stability profiling.
Tara M Mezzasalma, James K Kranz, Winnie Chan, Geoffrey T Struble, Céline Schalk-Hihi, Ingrid C Deckman

J Biomol Screen· April 2007

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Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.
Carsten Schubert, Céline Schalk-Hihi, Geoffrey T Struble, Hong-Chang Ma, Ioanna P Petrounia, Ingrid C Deckman

J Biol Chem· February 2007

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Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.
Céline Schalk-Hihi, Hong-Chang Ma, Geoffrey T Struble, Shariff Bayoumy, Robyn Williams, Ingrid C Deckman

J Biol Chem· February 2007

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Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity.
Jukka Kervinen, Hongchang Ma, Shariff Bayoumy, Carsten Schubert, Cynthia Milligan, Ingrid Deckman

Arch Biochem Biophys· May 2006

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Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.
Anna C Maroney, Juan J Marugan, Tara M Mezzasalma, Alexander N Barnakov, Thomas A Garrabrant, Ingrid C Deckman

Biochemistry· May 2006

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Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.
Lei Qiao, Christian A Baumann, Carl S Crysler, Nisha S Ninan, Marta C Abad, Ingrid C Deckman

Bioorg Med Chem Lett· January 2006

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Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.
Bruce L Grasberger, Tianbao Lu, Carsten Schubert, Daniel J Parks, Theodore E Carver, Ingrid C Deckman

J Med Chem· February 2005

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Design and synthesis of 4,5-disubstituted-thiophene-2-amidines as potent urokinase inhibitors.
M Jonathan Rudolph, Carl R Illig, Nalin L Subasinghe, Kenneth J Wilson, James B Hoffman, Ingrid C Deckman

Bioorg Med Chem Lett· February 2002

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