Publications by authors named "Inmaculada Posadas"

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Tuna Collagen-Based hydrogels for the targeted delivery of BET inhibitors and BET-PROTACs in breast cancer therapy.
Irene Sevilla-Carrillo, Carolina Hermida-Merino, Inmaculada Posadas, Martin Kreuzer, María Del Mar Noblejas-López

Eur J Pharm Biopharm· December 2025

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The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex.
Stefan Redl, Felix Von Zweydorf, Christian J Gloeckner, Inmaculada Posadas, Valentín Ceña

Sci Rep· November 2025

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Nanoparticles and siRNA: A new era in therapeutics?
María Dolores Pérez-Carrión, Inmaculada Posadas, Valentín Ceña

Pharmacol Res· March 2024

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A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells.
Cristina de la Torre, Pablo Játiva, Inmaculada Posadas, Darío Manzanares, José L Jiménez Blanco

Pharmaceutics· November 2022

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LRRK2 and Proteostasis in Parkinson's Disease.
María Dolores Pérez-Carrión, Inmaculada Posadas, Javier Solera, Valentín Ceña

Int J Mol Sci· June 2022

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Engineered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death.
Inmaculada Posadas, Laura Romero-Castillo, Rosa-Anna Ronca, Andrii Karpus, Serge Mignani

Int J Mol Sci· April 2022

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Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy.
Enrique Niza, Cristina Nieto-Jiménez, María Del Mar Noblejas-López, Iván Bravo, José Antonio Castro-Osma, Inmaculada Posadas

Nanomaterials (Basel)· August 2019

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Assessment of doxorubicin delivery devices based on tailored bare polycaprolactone against glioblastoma.
Enrique Niza, José A Castro-Osma, Inmaculada Posadas, Carlos Alonso-Moreno, Iván Bravo

Int J Pharm· March 2019

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Second Generation Amphiphilic Poly-Lysine Dendrons Inhibit Glioblastoma Cell Proliferation without Toxicity for Neurons or Astrocytes.
Jolanta Janiszewska, Inmaculada Posadas, Pablo Játiva, Marta Bugaj-Zarebska, Zofia Urbanczyk-Lipkowska

PLoS One· June 2017

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Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells.
Laura Gallego-Yerga, Inmaculada Posadas, Cristina de la Torre, Jesús Ruiz-Almansa, Francesco Sansone

Front Pharmacol· May 2017

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Synthesis, characterization, DNA interactions and antiproliferative activity on glioblastoma of iminopyridine platinum(II) chelate complexes.
Inmaculada Posadas, Carlos Alonso-Moreno, Iván Bravo, Fernando Carrillo-Hermosilla, Andrés Garzón

J Inorg Biochem· March 2017

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Nanoparticles for brain-specific drug and genetic material delivery, imaging and diagnosis.
Inmaculada Posadas, Silvia Monteagudo, Valentín Ceña

Nanomedicine (Lond)· April 2016

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The endoplasmic reticulum stress and the HIF-1 signalling pathways are involved in the neuronal damage caused by chemical hypoxia.
Beatriz López-Hernández, Valentin Ceña, Inmaculada Posadas

Br J Pharmacol· June 2015

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Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine.
Beatriz Moreno, Iciar Lopez, Begoña Fernández-Díez, Miroslav Gottlieb, Carlos Matute, Inmaculada Posadas

PLoS One· November 2014

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Nicotinic receptors in neurodegeneration.
Inmaculada Posadas, Beatriz López-Hernández, Valentín Ceña

Curr Neuropharmacol· May 2013

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Acetaminophen induces human neuroblastoma cell death through NFKB activation.
Inmaculada Posadas, Pablo Santos, Valentín Ceña

PLoS One· April 2013

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Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death.
Inmaculada Posadas, Francisco C Pérez-Martínez, Javier Guerra, Prado Sánchez-Verdú, Valentín Ceña

J Neurochem· February 2012

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HIF-1α is neuroprotective during the early phases of mild hypoxia in rat cortical neurons.
Beatriz López-Hernández, Inmaculada Posadas, Petar Podlesniy, María A Abad, Ramón Trullas

Exp Neurol· January 2012

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Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death.
Daniel Tornero, Inmaculada Posadas, Valentín Ceña

PLoS One· September 2011

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Barriers to non-viral vector-mediated gene delivery in the nervous system.
Francisco C Pérez-Martínez, Javier Guerra, Inmaculada Posadas, Valentín Ceña

Pharm Res· August 2011

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Acetaminophen induces apoptosis in rat cortical neurons.
Inmaculada Posadas, Pablo Santos, Almudena Blanco, Maríangeles Muñoz-Fernández, Valentín Ceña

PLoS One· December 2010

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Nonviral vectors for the delivery of small interfering RNAs to the CNS.
Inmaculada Posadas, Francisco Javier Guerra, Valentín Ceña

Nanomedicine (Lond)· October 2010

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Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity.
Inmaculada Posadas, Beatriz López-Hernández, Maria Isabel Clemente, Jose Luis Jiménez, Paula Ortega

Pharm Res· May 2009

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Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro.
Francesca Borrelli, Inmaculada Posadas, Raffaele Capasso, Gabriella Aviello, Valeria Ascione

Eur J Pharmacol· October 2005

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Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo.
Mariarosaria Bucci, Fiorentina Roviezzo, Inmaculada Posadas, Jun Yu, Luca Parente

Proc Natl Acad Sci U S A· January 2005

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