Publications by authors named "Inmaculada Robina"

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Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes.
Marina Carranza, Ana T Carmona, Claudio D Navo, Inmaculada Robina, Simone Fratta

Org Lett· October 2023

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Transferring Substituents from Alkynes to Furans and Pyrroles through Heteronorbornadienes as Intermediates: Synthesis of β-Substituted Pyrroles/Furans.
Javier García-Domínguez, Marina Carranza, Edijs Jansons, Ana T Carmona, Inmaculada Robina

J Org Chem· September 2023

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Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer.
Simone Fratta, Paulina Biniecka, Antonio J Moreno-Vargas, Ana T Carmona, Aimable Nahimana, Inmaculada Robina

Eur J Med Chem· March 2023

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Studies on the Regioselective Rearrangement of Azanorbornanic Aminyl Radicals into 2,8-Diazabicyclo[3.2.1]oct-2-ene Systems.
Enrique Gil de Montes, Matteo A Tallarida, Ana T Carmona, Claudio D Navo, Inmaculada Robina

J Org Chem· December 2022

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Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
Jian-Fei Bai, Somi Reddy Majjigapu, Bernard Sordat, Sophie Poty, Pierre Vogel, Inmaculada Robina

Eur J Med Chem· September 2022

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STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket.
Serena Monaco, Jonathan Ramírez-Cárdenas, Ana Teresa Carmona, Inmaculada Robina, Jesus Angulo

Pharmaceuticals (Basel)· August 2022

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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors.
Jorge Franco, Francesco Piacente, Melanie Walter, Simone Fratta, Moustafa Ghanem, Inmaculada Robina

Pharmaceuticals (Basel)· July 2022

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Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars.
Valeria Pingitore, Macarena Martínez-Bailén, Ana T Carmona, Zuzana Mészáros, Natalia Kulik, Inmaculada Robina

Bioorg Chem· March 2022

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Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.
Giovanna Sociali, Nara Liessi, Alessia Grozio, Irene Caffa, Marco Daniele Parenti, Inmaculada Robina

Mol Divers· August 2020

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Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B.
Serena Monaco, Samuel Walpole, Hassan Doukani, Ridvan Nepravishta, Macarena Martínez-Bailén, Inmaculada Robina

Chemistry· August 2020

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Regioselectivity of the 1,3-Dipolar Cycloaddition of Organic Azides to 7-Heteronorbornadienes. Synthesis of β-Substituted Furans/Pyrroles.
Enrique Gil de Montes, Macarena Martı Nez-Bailén, Ana T Carmona, Inmaculada Robina, Antonio J Moreno-Vargas

J Org Chem· July 2020

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Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation.
Enrique Gil de Montes, Alena Istrate, Claudio D Navo, Ester Jiménez-Moreno, Emily A Hoyt, Inmaculada Robina

Angew Chem Int Ed Engl· April 2020

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Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease.
Macarena Martínez-Bailén, Ana T Carmona, Francesca Cardona, Camilla Matassini, Andrea Goti, Inmaculada Robina

Eur J Med Chem· April 2020

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Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars.
Macarena Martínez-Bailén, Elena Jiménez-Ortega, Ana T Carmona, Inmaculada Robina, Julia Sanz-Aparicio

Bioorg Chem· August 2019

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Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition.
Macarena Martínez-Bailén, Ana T Carmona, Athéna C Patterson-Orazem, Raquel L Lieberman, Daisuke Ide, Inmaculada Robina

Bioorg Chem· May 2019

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Azabicyclic vinyl sulfones for residue-specific dual protein labelling.
Enrique Gil de Montes, Ester Jiménez-Moreno, Bruno L Oliveira, Claudio D Navo, Pedro M S D Cal, Inmaculada Robina

Chem Sci· April 2019

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Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine-(Thio)urea Hybrid Molecules Generated via Click Chemistry.
Pilar Elías-Rodríguez, Valeria Pingitore, Ana T Carmona, Antonio J Moreno-Vargas, Daisuke Ide, Inmaculada Robina

J Org Chem· August 2018

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Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors.
Ana T Carmona, Sebastián Carrión-Jiménez, Valeria Pingitore, Elena Moreno-Clavijo, Inmaculada Robina

Eur J Med Chem· May 2018

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Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.
Claudia Bello, Jianfei Bai, Bartosz K Zambron, Pilar Elías-Rodríguez, Consuelo Gajate, Inmaculada Robina

Eur J Med Chem· April 2018

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Epididymal α-l-fucosidase and its possible role in remodelling the surface of bull spermatozoa.
Andrea Carolina Aguilera, Veronica Boschin, Inmaculada Robina, Pilar Elías-Rodríguez, Miguel Angel Sosa

Theriogenology· December 2017

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Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases.
Stefania Mirabella, Giampiero D'Adamio, Camilla Matassini, Andrea Goti, Sandra Delgado, Inmaculada Robina

Chemistry· October 2017

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Tuning of β-glucosidase and α-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules.
Macarena Martínez-Bailén, Ana T Carmona, Elena Moreno-Clavijo, Inmaculada Robina, Daisuke Ide

Eur J Med Chem· September 2017

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Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines.
Audrey Hottin, Sebastián Carrión-Jiménez, Elena Moreno-Clavijo, Antonio J Moreno-Vargas, Ana T Carmona, Inmaculada Robina

Org Biomol Chem· March 2016

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Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar.
Camilla Matassini, Stefania Mirabella, Andrea Goti, Inmaculada Robina, Antonio J Moreno-Vargas

Beilstein J Org Chem· January 2016

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Reversibility of the interactions between a novel surfactant derived from lysine and biomolecules.
Victoria Isabel Martín, Beatriz Sarrión, Manuel López-López, Pilar López-Cornejo, Inmaculada Robina

Colloids Surf B Biointerfaces· November 2015

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