Publications by authors named "Insoo Yoon"

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Solcumin™: a functional hybrid particle with potent anti-inflammatory and antioxidant activities and enhanced storage stability.
Jinhee Jeong, Sujin Hwang, Chan Hee Lee, Chan Yang Lee, Byoung Seung Jeon, In-Soo Yoon

Pharmacol Rep· December 2025

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Benzoxazole Derivatives as Potent FXR and PPARα Dual Agonists With Anti-Fibrotic and Metabolic Regulatory Effects.
Mi-Jeong Kim, Dong-Gyun Han, Hyeon Seo Park, Sugyeong Ha, Sang Gyun Noh, In-Soo Yoon

MedComm (2020)· November 2025

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Pharmacokinetic and Bioequivalence Evaluation of Two Sitagliptin Tablets With Different Salts in Healthy Subjects.
Usok Hyun, Seongnam Chu, Sungyun Kim, Jung-Ki Hong, Taeyoung Kim, In-Soo Yoon

Clin Pharmacol Drug Dev· October 2025

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Leukocyte Esterase-Activated Nanoconjugates Enables Precise Local Therapy of Ulcerative Colitis via Inflamed Tissue-Selective Drug Delivery.
Juho Lee, Aruzhan Saparbayeva, Jihyun Kim, Dongmin Kwak, Hyunwoo Kim, In-Soo Yoon

ACS Appl Mater Interfaces· September 2025

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Estimation of BPA, BPS, and BPF exposure levels in the general Korean population using the physiologically-based toxicokinetic model and human urinary biomonitoring for risk assessment.
Min-Ju Kim, Yong-Kook Kwon, Hyung-Jun Kim, Dong-Gyun Han, In-Soo Yoon

Int J Hyg Environ Health· August 2025

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Colon-Targeted β-Adrenoceptor Agonist Mirabegron Enhances Anticolitic Potency of the Drug via Potentiating the Nrf2-HO-1 Pathway.
Jaejeong Kim, Changyu Kang, Jin-Wook Yoo, In-Soo Yoon, Yunjin Jung

Mol Pharm· May 2025

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In vitro and in vivo efficacy studies of an engineered endolysin targeting Gram-negative pathogens.
Hye-Won Hong, Jaeyeon Jang, Young Deuk Kim, Tae-Hwan Jeong, Dogeun Lee, In-Soo Yoon, Hyunjin Yoon

Int J Biol Macromol· April 2025

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Elucidating a Tumor-Selective Nanoparticle Delivery Mechanism at the Colorectal Lumen-Tumor Interface for Precise Local Cancer Therapy.
Juho Lee, Dongmin Kwak, Hyunwoo Kim, Muneeb Ullah, Jihyun Kim, In-Soo Yoon

Small· March 2025

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Hypoxia increases methylated histones to prevent histone clipping and heterochromatin redistribution during Raf-induced senescence.
Soojeong Chang, Ramhee Moon, Dowoon Nam, Sang-Won Lee, Insoo Yoon

Nucleic Acids Res· January 2025

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Author Correction: 3C methods in cancer research: recent advances and future prospects.
Insoo Yoon, Uijin Kim, Kyung Oh Jung, Yousuk Song, Taesoo Park

Exp Mol Med· November 2024

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A simple and sensitive high-performance liquid chromatographic method combined with fluorescence detection for bioanalysis of scopoletin in rat plasma: Application to a pharmacokinetic study.
Taeyoung Kim, Dong-Gyun Han, In-Soo Yoon

Biomed Chromatogr· October 2024

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3C methods in cancer research: recent advances and future prospects.
Insoo Yoon, Uijin Kim, Kyung Oh Jung, Yousuk Song, Taesoo Park

Exp Mol Med· April 2024

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N-Succinylaspartic-Acid-Conjugated Riluzole Is a Safe and Potent Colon-Targeted Prodrug of Riluzole against DNBS-Induced Rat Colitis.
Jaejeong Kim, Changyu Kang, Jin-Wook Yoo, In-Soo Yoon, Yunjin Jung

Pharmaceutics· November 2023

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A High-Performance Liquid Chromatography with Photodiode Array Detection Method for Simultaneous Determination of Three Compounds Isolated from : Assessment of the Effects on Cytochrome P450-Mediated Metabolism In Vitro and In Vivo.
Min-Ji Keem, Seong-Wook Seo, Taeyoung Kim, Beom-Geun Jo, Su-Nam Kim, In-Soo Yoon

Nutrients· September 2023

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Physicochemical characterization and phase II metabolic profiling of echinochrome A, a bioactive constituent from sea urchin, and its physiologically based pharmacokinetic modeling in rats and humans.
Dong-Gyun Han, Jinsook Kwak, Eugene Choi, Seong-Wook Seo, Elena A Vasileva, In-Soo Yoon

Biomed Pharmacother· June 2023

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Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC-MS/MS method: In vitro, in situ, and in vivo evaluations.
Seong-Wook Seo, Dong-Gyun Han, Young Mee Baek, Min Chul Park, Jin-Wook Yoo, In-Soo Yoon

Drug Dev Res· May 2023

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pH-sustaining nanostructured hydroxyapatite/alginate composite hydrogel for gastric protection and intestinal release of GG.
Jihyun Kim, Shwe Phyu Hlaing, Juho Lee, Dongmin Kwak, Hyunwoo Kim, In-Soo Yoon

Bioeng Transl Med· May 2023

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N-Acetylserotonin is an oxidation-responsive activator of Nrf2 ameliorating colitis in rats.
Changyu Kang, Seongkeun Jeong, Jaejeong Kim, Sanghyun Ju, Eunok Im, In-Soo Yoon

J Pineal Res· January 2023

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5-Fluorouracil crystal-incorporated, pH-responsive, and release-modulating PLGA/Eudragit FS hybrid microparticles for local colorectal cancer-targeted chemotherapy.
Juho Lee, Junhwan Bae, Dongmin Kwak, Hyunwoo Kim, Jihyun Kim, In-Soo Yoon

Int J Pharm· January 2023

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Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: , , and evaluations.
Seong-Wook Seo, Dong-Gyun Han, Eugene Choi, Min-Jeong Seo, Im-Sook Song, In-Soo Yoon

Pharm Biol· December 2022

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Determination of Leuprolide-Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats.
Gi-Sang Seong, Seong-Wook Seo, Ji Young Cho, Kye Wan Lee, Beom-Jin Lee, In-Soo Yoon

Molecules· December 2022

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Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A.
Changyu Kang, Jaejeong Kim, Sanghyun Ju, Heeyeong Cho, Hyun Young Kim, In-Soo Yoon

Pharmaceutics· December 2022

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Donepezil hydrochloride-reinforced cellulose nanocrystal-aggregated gel structure for long-acting drug delivery.
Da In Jeong, Sungyun Kim, Min-Hwan Kim, In-Soo Yoon, Seung-Hwan Lee

Carbohydr Polym· November 2022

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Bacteria-Adhesive Nitric Oxide-Releasing Graphene Oxide Nanoparticles for MRPA-Infected Wound Healing Therapy.
Jiafu Cao, Shwe Phyu Hlaing, Juho Lee, Jihyun Kim, Eun Hee Lee, In-Soo Yoon

ACS Appl Mater Interfaces· November 2022

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Fractional transit compartment model for describing drug delayed response to tumors using Mittag-Leffler distribution on age-structured PKPD model.
Jong Hyuk Byun, Yunil Roh, In-Soo Yoon, Kwang Su Kim, Il Hyo Jung

PLoS One· November 2022

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