Publications by authors named "Ionel Sandovici"

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Loss of choroid plexus-derived insulin-like growth factor 2 (IGF2) leads to hyposmia, while retaining post-partum mood resilience in mice.
Hollian R Phillipps, Eleni C R Hackwell, Ionel Sandovici, Miguel Constância, David R Grattan

J Neuroendocrinol· September 2025

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Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities.
Ionel Sandovici, Tiago Morais, Miguel Constância, Mariana P Monteiro

J Endocr Soc· September 2025

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Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Ionel Sandovici, Denise S Fernandez-Twinn, Niamh Campbell, Wendy N Cooper, Yoichi Sekita

Cell Rep· September 2024

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A genetically small fetus impairs placental adaptations near term.
Ionel Sandovici, Olatejumoye Knee, Jorge Lopez-Tello, Norman Shreeve, Abigail L Fowden

Dis Model Mech· August 2024

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Neuronal activity drives IGF2 expression from pericytes to form long-term memory.
Kiran Pandey, Benjamin Bessières, Susan L Sheng, Julian Taranda, Pavel Osten, Ionel Sandovici

Neuron· December 2023

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Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene.
Jorge Lopez-Tello, Hannah E J Yong, Ionel Sandovici, Georgina K C Dowsett, Efthimia R Christoforou

Cell Metab· July 2023

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Protocol to isolate and culture primary mouse feto-placental endothelial cells.
Ionel Sandovici, Moritz Reiterer, Miguel Constância, Cristina M Branco

STAR Protoc· December 2022

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Sex differences in the intergenerational inheritance of metabolic traits.
Ionel Sandovici, Denise S Fernandez-Twinn, Antonia Hufnagel, Miguel Constância, Susan E Ozanne

Nat Metab· May 2022

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Adipose Tissue Epigenetic Profile in Obesity-Related Dysglycemia - A Systematic Review.
Sara Andrade, Tiago Morais, Ionel Sandovici, Alexandre L Seabra, Miguel Constância

Front Endocrinol (Lausanne)· January 2022

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The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth.
Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello

Dev Cell· January 2022

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Placental secretome characterization identifies candidates for pregnancy complications.
Tina Napso, Xiaohui Zhao, Marta Ibañez Lligoña, Ionel Sandovici, Richard G Kay

Commun Biol· June 2021

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Autocrine IGF2 programmes β-cell plasticity under conditions of increased metabolic demand.
Ionel Sandovici, Constanze M Hammerle, Sam Virtue, Yurena Vivas-Garcia, Adriana Izquierdo-Lahuerta

Sci Rep· April 2021

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Deletion of the Imprinted Gene Increases Placental Passive Permeability in the Mouse.
Emily Angiolini, Ionel Sandovici, Philip M Coan, Graham J Burton, Colin P Sibley

Genes (Basel)· April 2021

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Analysis of Histone Modifications in Rodent Pancreatic Islets by Native Chromatin Immunoprecipitation.
Ionel Sandovici, Lisa M Nicholas, Laura P O'Neill

Methods Mol Biol· December 2020

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Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.
Constanze M Hammerle, Ionel Sandovici, Gemma V Brierley, Nicola M Smith, Warren E Zimmer

PLoS Genet· October 2020

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Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta.
Agnes Wieczorek, Clara V Perani, Mark Nixon, Miguel Constancia, Ionel Sandovici

Am J Physiol Endocrinol Metab· July 2019

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Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice.
Jorge López-Tello, Vicente Pérez-García, Jaspreet Khaira, Laura C Kusinski, Wendy N Cooper, Ionel Sandovici

Elife· June 2019

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Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine.
Amber N Ziegler, Qiang Feng, Shravanthi Chidambaram, Jaimie M Testai, Ekta Kumari, Ionel Sandovici

Stem Cell Reports· April 2019

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Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth.
Amanda N Sferruzzi-Perri, Ionel Sandovici, Miguel Constancia, Abigail L Fowden

J Physiol· August 2017

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Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p'-DDE.
Diogo Pestana, Diana Teixeira, Manuela Meireles, Cláudia Marques, Sónia Norberto, Ionel Sandovici

Sci Rep· June 2017

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Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets.
Ionel Sandovici, Constanze M Hammerle, Wendy N Cooper, Noel H Smith, Jane L Tarry-Adkins

Diabetologia· March 2016

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Extracardiac control of embryonic cardiomyocyte proliferation and ventricular wall expansion.
Hua Shen, Susana Cavallero, Kristine D Estrada, Ionel Sandovici, S Ram Kumar

Cardiovasc Res· March 2015

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Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes.
Ionel Sandovici, Constanze M Hammerle, Susan E Ozanne, Miguel Constância

Cell Mol Life Sci· May 2013

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Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.
Victoria L Haley, David J Barnes, Ionel Sandovici, Miguel Constancia, Christopher F Graham

EMBO Mol Med· August 2012

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Placental adaptations to the maternal-fetal environment: implications for fetal growth and developmental programming.
Ionel Sandovici, Katharina Hoelle, Emily Angiolini, Miguel Constância

Reprod Biomed Online· July 2012

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