Publications by authors named "Irem Ulku"

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Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway.
Irem Ulku, Fatima El Ansari, Mark A Hancock, Hedi Zhou, Gael Cagnone

Proc Natl Acad Sci U S A· November 2025

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Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expression.
Irem Ulku, Rocher Leung, Fritz Herre, Lina Walther, Adeola Shobo

J Biol Chem· August 2024

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Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.
Irem Ulku, Filip Liebsch, S Can Akerman, Jana F Schulz, Luka Kulic

Sci Rep· February 2023

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Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.
Lisa Gallwitz, Lina Schmidt, André R A Marques, Andreas Tholey, Liam Cassidy, Irem Ulku

Neurobiol Dis· December 2022

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Etoposide Loaded SPION-PNIPAM Nanoparticles Improve the in vitro Therapeutic Outcome on Metastatic Prostate Cancer Cells via Enhanced Apoptosis.
Merve Erkisa, Ferda Ari, Irem Ulku, Rouhollah Khodadust, Yasemin Yar

Chem Biodivers· November 2020

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Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.
Filip Liebsch, Luka Kulic, Charlotte Teunissen, Adeola Shobo, Irem Ulku

Nat Commun· May 2019

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Sparse representations for online-learning-based hyperspectral image compression.
İrem Ülkü, Behçet Uğur Töreyin

Appl Opt· October 2015

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