Publications by authors named "Irina Ingold"

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A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.
Svenja M Lorenz, Adam Wahida, Mark J Bostock, Tobias Seibt, André Santos Dias Mourão, Irina Ingold

Cell· December 2025

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Author Correction: Targeting ferroptosis protects against experimental (multi)organ dysfunction and death.
Samya Van Coillie, Emily Van San, Ines Goetschalckx, Bartosz Wiernicki, Banibrata Mukhopadhyay, Irina Ingold

Nat Commun· September 2025

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Repression of ferroptotic cell death by mitochondrial calcium signaling.
Jianwen Chen, Bao Zhao, Shen Wang, Anjun Ma, Hong Dong, Irina Ingold

Res Sq· July 2023

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GPX4: old lessons, new features.
Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Irina Ingold

Biochem Soc Trans· June 2022

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Targeting ferroptosis protects against experimental (multi)organ dysfunction and death.
Samya Van Coillie, Emily Van San, Ines Goetschalckx, Bartosz Wiernicki, Banibrata Mukhopadhyay, Irina Ingold

Nat Commun· February 2022

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Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4.
Noelia Fradejas-Villar, Wenchao Zhao, Uschi Reuter, Michael Doengi, Irina Ingold

Redox Biol· December 2021

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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mässenhausen, Irina Ingold

Nat Commun· July 2021

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FSP1 is a glutathione-independent ferroptosis suppressor.
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold

Nature· November 2019

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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.
Behrouz Hassannia, Bartosz Wiernicki, Irina Ingold, Feng Qu, Simon Van Herck

J Clin Invest· August 2018

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Selenium and iron, two elemental rivals in the ferroptotic death process.
Irina Ingold, Marcus Conrad

Oncotarget· April 2018

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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
Irina Ingold, Carsten Berndt, Sabine Schmitt, Sebastian Doll, Gereon Poschmann

Cell· January 2018

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold

Nat Chem Biol· January 2017

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Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth.
Sung Eun Kim, Li Zhang, Kai Ma, Michelle Riegman, Feng Chen, Irina Ingold

Nat Nanotechnol· November 2016

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Human thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration.
Eliska Holzerova, Katharina Danhauser, Tobias B Haack, Laura S Kremer, Marlen Melcher, Irina Ingold

Brain· February 2016

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A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair.
Michèle Telorack, Michael Meyer, Irina Ingold, Marcus Conrad, Wilhelm Bloch

PLoS Genet· January 2016

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ROS, thiols and thiol-regulating systems in male gametogenesis.
Marcus Conrad, Irina Ingold, Katalin Buday, Sho Kobayashi, Jose Pedro Friedmann Angeli

Biochim Biophys Acta· August 2015

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Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility.
Irina Ingold, Michaela Aichler, Elena Yefremova, Antonella Roveri, Katalin Buday

J Biol Chem· June 2015

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Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Juliane Hellfritsch, Julian Kirsch, Manuela Schneider, Tamara Fluege, Markus Wortmann, Irina Ingold

Antioxid Redox Signal· April 2015

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