Publications by authors named "Irina Zueva"

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Targeted delivery of 2-PAM to the brain using cationic liposomes modified with lipid-like surfactants for the treatment of acute organophosphorus poisoning.
Darya A Kuznetsova, Denis M Kuznetsov, Gulnara A Gaynanova, Irina V Zueva, Vasily M Babaev

Chem Biol Interact· October 2025

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Disease-modifying effect of donepezil on APP/PS1 mice at different stages of Alzheimer's disease.
Irina Zueva, Grigory Belyaev, Konstantin Petrov

Mol Cell Biochem· September 2025

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Ionic and Non-Ionic Counterparts Based on Bis(Uracilyl)Alkane Moiety with Highest Selectivity Towards Acetylcholinesterase for Protection Against Organophosphate Poisoning and Treating Alzheimer's Disease.
Irina V Zueva, Liliya F Saifina, Liliya M Gubaidullina, Marina M Shulaeva, Alexandra D Kharlamova

Int J Mol Sci· April 2025

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Design of reversible cholinesterase inhibitors: Fine-tuning of enzymatic activity by PAMAM-calix-dendrimers.
Igor Shiabiev, Dmitry Pysin, Alexandra Kharlamova, Irina Zueva, Konstantin Petrov

Int J Biol Macromol· January 2025

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Conjugation of Triterpenic Acids with 3-Aminoquinuclidine Moiety: An Approach to Acetylcholinesterase Mixed or Uncompetitive Type Inhibitors.
Anastasiya V Petrova, Ha T T Nguyen, Irina V Zueva, Konstantin A Petrov, Alexander N Lobov

Molecules· December 2024

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Conjugates of nucleobases with triazole-hydroxamic acids for the reactivation of acetylcholinesterase and treatment of delayed neurodegeneration induced by organophosphate poisoning.
Marina M Shulaeva, Irina V Zueva, Anton E Nikolaev, Liliya F Saifina, Dilyara R Sharafutdinova

Bioorg Chem· December 2023

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Can Activation of Acetylcholinesterase by β-Amyloid Peptide Decrease the Effectiveness of Cholinesterase Inhibitors?
Irina V Zueva, Elmira A Vasilieva, Gulnara A Gaynanova, Andrey V Moiseenko, Anna D Burtseva

Int J Mol Sci· November 2023

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Synthesis, Properties, and Biomedical Application of Dicationic Gemini Surfactants with Dodecane Spacer and Carbamate Fragments.
Leysan Vasileva, Gulnara Gaynanova, Farida Valeeva, Elvira Romanova, Rais Pavlov, Irina Zueva

Int J Mol Sci· August 2023

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Mitochondria-Targeted Delivery Strategy of Dual-Loaded Liposomes for Alzheimer's Disease Therapy.
Leysan Vasileva, Gulnara Gaynanova, Farida Valeeva, Grigory Belyaev, Irina Zueva

Int J Mol Sci· June 2023

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The Formation of Morphologically Stable Lipid Nanocarriers for Glioma Therapy.
Rais Pavlov, Elvira Romanova, Denis Kuznetsov, Anna Lyubina, Syumbelya Amerhanova, Irina Zueva

Int J Mol Sci· February 2023

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Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning.
Liliya F Saifina, Mohnad Abdalla, Liliya M Gubaidullina, Irina V Zueva, Wafa Ali Eltayb

Eur J Med Chem· January 2023

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Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes.
Elmira A Vasilieva, Darya A Kuznetsova, Farida G Valeeva, Denis M Kuznetsov, Andrey V Zakharov, Irina V Zueva

Pharmaceutics· December 2022

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Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer's Disease.
Vyacheslav E Semenov, Irina V Zueva, Sofya V Lushchekina, Eduard G Suleimanov, Liliya M Gubaidullina

Molecules· November 2022

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Transdermal Delivery of 2-PAM as a Tool to Increase the Effectiveness of Traditional Treatment of Organophosphate Poisoning.
Leysan Vasileva, Gulnara Gaynanova, Irina Zueva, Anna Lyubina, Syumbelya Amerhanova

Int J Mol Sci· November 2022

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Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning.
Darya A Kuznetsova, Gulnara A Gaynanova, Elmira A Vasilieva, Rais V Pavlov, Irina V Zueva

Pharmaceutics· September 2022

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α-tocopherol, a slow-binding inhibitor of acetylcholinesterase.
Irina Zueva, Sofya Lushchekina, Polina Shulnikova, Oksana Lenina, Konstantin Petrov

Chem Biol Interact· October 2021

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Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments.
Irina Zueva, Oksana Lenina, Ramilya Kayumova, Konstantin Petrov, Patrick Masson

Chem Biol Interact· August 2021

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Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat.
Daina N Buzyurova, Tatiana N Pashirova, Irina V Zueva, Evgenia A Burilova, Zukhra M Shaihutdinova

Toxicology· November 2020

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1-(3--Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies.
Irina V Zueva, Sofya V Lushchekina, Ian R Pottie, Sultan Darvesh, Patrick Masson

Biomolecules· November 2020

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Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning.
Oksana A Lenina, Irina V Zueva, Vladimir V Zobov, Vyacheslav E Semenov, Patrick Masson

Sci Rep· October 2020

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Biomedical potentialities of cationic geminis as modulating agents of liposome in drug delivery across biological barriers and cellular uptake.
Rais V Pavlov, Gulnara A Gaynanova, Darya A Kuznetsova, Leysan A Vasileva, Irina V Zueva

Int J Pharm· September 2020

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Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease.
Vyacheslav E Semenov, Irina V Zueva, Marat A Mukhamedyarov, Sofya V Lushchekina, Elena O Petukhova

Molecules· September 2020

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Bi-functional sterically hindered phenol lipid-based delivery systems as potential multi-target agents against Alzheimer's disease via an intranasal route.
Evgenia A Burilova, Tatiana N Pashirova, Irina V Zueva, Elmira M Gibadullina, Sofya V Lushchekina

Nanoscale· July 2020

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Steady-State Kinetics of Enzyme-Catalyzed Hydrolysis of Echothiophate, a P-S Bonded Organophosphorus as Monitored by Spectrofluorimetry.
Irina V Zueva, Sofya V Lushchekina, David Daudé, Eric Chabrière, Patrick Masson

Molecules· March 2020

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Water-soluble betaines and amines based on thiacalix[4]arene scaffold as new cholinesterase inhibitors.
Pavel L Padnya, Egor E Bayarashov, Irina V Zueva, Sofya V Lushchekina, Oksana A Lenina

Bioorg Chem· January 2020

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