Publications by authors named "Iris Alroy"

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Discovery of Small Molecules That Inhibit MYC mRNA Translation Through hnRNPK and Induction of Stress Granule-Mediated mRNA Relocalization.
Yoni Sheinberger, Rina Wassermann, Jasmine Khier, Ephrem Kassa, Linoy Vaturi, Iris Alroy

Int J Mol Sci· August 2025

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Virtual plates: Getting the best out of high content screens.
Inbal Shapira Lots, Iris Alroy

SLAS Discov· January 2024

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Expanding small-molecule target space to mRNA translation regulation.
Iris Alroy, Wissam Mansour, Mordehay Klepfish, Yoni Sheinberger

Drug Discov Today· March 2021

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ELX-02 Generates Protein via Premature Stop Codon Read-Through without Inducing Native Stop Codon Read-Through Proteins.
Daniel K Crawford, Iris Alroy, Neal Sharpe, Matthew M Goddeeris, Greg Williams

J Pharmacol Exp Ther· August 2020

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The novel aminoglycoside, ELX-02, permits CTNSW138X translational read-through and restores lysosomal cystine efflux in cystinosis.
Emma J Brasell, Lee Lee Chu, Murielle M Akpa, Idit Eshkar-Oren, Iris Alroy

PLoS One· March 2020

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Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds.
Lilach Vaks, Dana Litvak-Greenfeld, Stav Dror, LeeRon Shefet-Carasso, Galia Matatov, Iris Alroy

Antibodies (Basel)· July 2018

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Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction.
Christian Gratzke, Tomi Streng, Christian G Stief, Iris Alroy, Brian J Limberg

J Urol· February 2011

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Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats.
Christian Gratzke, Tomi Streng, Christian G Stief, Thomas R Downs, Iris Alroy

Eur Urol· June 2010

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Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine.
Zhe Yang, Karin R Aubrey, Iris Alroy, Robert J Harvey, Robert J Vandenberg

Biochem Pharmacol· October 2008

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The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp.
Shmuel Tuvia, Daniel Taglicht, Omri Erez, Iris Alroy, Iris Alchanati

J Cell Biol· April 2007

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The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production.
Iris Alroy, Shmuel Tuvia, Tsvika Greener, Daphna Gordon, Haim M Barr

Proc Natl Acad Sci U S A· February 2005

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Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.
Ido Amit, Liat Yakir, Menachem Katz, Yaara Zwang, Mina D Marmor, Iris Alroy

Genes Dev· July 2004

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Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.
Ami Citri, Iris Alroy, Sara Lavi, Chanan Rubin, Wanping Xu

EMBO J· May 2002

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