Publications by authors named "Iris D Young"

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Serial-femtosecond crystallography reveals how a phytochrome variant couples chromophore and protein structural changes.
Luisa Sauthof, Michal Szczepek, Andrea Schmidt, Asmit Bhowmick, Medhanjali Dasgupta, Iris D Young

Sci Adv· May 2025

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: a suite for processing serial crystallographic data.
Aaron S Brewster, Daniel W Paley, Asmit Bhowmick, David W Mittan-Moreau, Iris D Young

bioRxiv· May 2025

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ExaFEL: extreme-scale real-time data processing for X-ray free electron laser science.
Johannes P Blaschke, Robert Bolotovsky, Aaron S Brewster, Jeffrey Donatelli, Antoine DuJardin, Iris D Young

Front High Perform Comput· October 2024

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Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young

Elife· June 2024

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Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young

bioRxiv· March 2024

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Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography.
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Iris D Young

Sci Adv· March 2024

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Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography.
Alexander M Wolff, Eriko Nango, Iris D Young, Aaron S Brewster, Minoru Kubo

Nat Chem· November 2023

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Interpreting macromolecular diffraction through simulation.
Iris D Young, Derek Mendez, Billy K Poon, Johannes P Blaschke, Felix Wittwer

Methods Enzymol· September 2023

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Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography.
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Iris D Young

bioRxiv· August 2023

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De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Guillaume Tetreau, Michael R Sawaya, Elke De Zitter, Elena A Andreeva, Anne-Sophie Banneville, Iris D Young

Nat Commun· July 2022

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Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Kaitlyn Tsai, Vanja Stojković, D John Lee, Iris D Young, Teresa Szal

Nat Struct Mol Biol· February 2022

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Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.
Kaitlyn Tsai, Vanja Stojković, Lianet Noda-Garcia, Iris D Young, Alexander G Myasnikov

Elife· January 2022

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Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Stephen M Keable, Adrian Kölsch, Philipp S Simon, Medhanjali Dasgupta, Ruchira Chatterjee, Iris D Young

Sci Rep· November 2021

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Structural dynamics in the water and proton channels of photosystem II during the S to S transition.
Rana Hussein, Mohamed Ibrahim, Asmit Bhowmick, Philipp S Simon, Ruchira Chatterjee, Iris D Young

Nat Commun· November 2021

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X-ray free-electron laser studies reveal correlated motion during isopenicillin synthase catalysis.
Patrick Rabe, Jos J A G Kamps, Kyle D Sutherlin, James D S Linyard, Pierre Aller, Iris D Young

Sci Adv· August 2021

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STEM Pride: Perspectives from transgender, nonbinary, and genderqueer scientists.
Adam Armada-Moreira, Carrie Cizauskas, Gabriela Fleury, Sofia Kirke Forslund, Eartha Mae Guthman, Iris D Young

Cell· June 2021

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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Meghna Gupta, Caleigh M Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Iris D Young

bioRxiv· May 2021

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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Meghna Gupta, Caleigh M Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Iris D Young

Res Sq· May 2021

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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Iris D Young

Sci Adv· April 2021

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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
David E Gordon, Joseph Hiatt, Mehdi Bouhaddou, Veronica V Rezelj, Svenja Ulferts, Iris D Young

Science· December 2020

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Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Iris D Young

bioRxiv· November 2020

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Untangling the sequence of events during the S → S transition in photosystem II and implications for the water oxidation mechanism.
Mohamed Ibrahim, Thomas Fransson, Ruchira Chatterjee, Mun Hon Cheah, Rana Hussein, Iris D Young

Proc Natl Acad Sci U S A· June 2020

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Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit.
Vanja Stojković, Alexander G Myasnikov, Iris D Young, Adam Frost, James S Fraser

Nucleic Acids Res· March 2020

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Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Guillaume Tetreau, Anne-Sophie Banneville, Elena A Andreeva, Aaron S Brewster, Mark S Hunter, Iris D Young

Nat Commun· March 2020

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Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.
Alexander M Wolff, Iris D Young, Raymond G Sierra, Aaron S Brewster, Michael W Martynowycz

IUCrJ· March 2020

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