Publications by authors named "Iris Heer"

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Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling.
Wies R Vallentgoed, Youri Hoogstrate, Karin A van Garderen, Levi van Hijfte, Erik van Dijk, Iris de Heer

Nat Cancer· October 2025

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The Influence of Electroencephalographic Density Spectral Array Guidance of Sevoflurane Administration on Recovery From General Anesthesia in Children. A Randomized Controlled Trial.
Iris J de Heer, Hannah A C Raab, Joost de Vries, Gulhan Karaöz-Bulut, Frank Weber

Paediatr Anaesth· April 2025

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Gemistocytic tumor cells programmed for glial scarring characterize T cell confinement in IDH-mutant astrocytoma.
Levi van Hijfte, Marjolein Geurts, Iris de Heer, Santoesha A Ghisai, Hayri E Balcioglu

Nat Commun· January 2025

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Epigenetic landscape reorganisation and reactivation of embryonic development genes are associated with malignancy in IDH-mutant astrocytoma.
Santoesha A Ghisai, Levi van Hijfte, Wies R Vallentgoed, C Mircea S Tesileanu, Iris de Heer

Acta Neuropathol· October 2024

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Electroencephalographic density spectral array monitoring during propofol/sevoflurane coadministration in children, an exploratory observational study.
Iris J de Heer, Hannah A C Raab, Stephan Krul, Gulhan Karaöz-Bulut, Robert-Jan Stolker

Anaesth Crit Care Pain Med· April 2024

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Epigenetic landscape reorganization and reactivation of embryonic development genes are associated with malignancy in IDH-mutant astrocytoma.
Santoesha A Ghisai, Levi van Hijfte, Wies R Vallentgoed, C Mircea S Tesileanu, Iris de Heer

bioRxiv· March 2024

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Longitudinal characteristics of T2-FLAIR mismatch in IDH-mutant astrocytomas: Relation to grade, histopathology, and overall survival in the GLASS-NL cohort.
Karin A van Garderen, Wies R Vallentgoed, Anna Lavrova, Johanna M Niers, Wendy W J de Leng, Iris de Heer

Neurooncol Adv· November 2023

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Electroencephalographic Density Spectral Array monitoring in pediatric anesthesia: clinical background and practical applications.
Iris J de Heer, Frank Weber

Minerva Anestesiol· April 2023

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Transcriptome analysis reveals tumor microenvironment changes in glioblastoma.
Youri Hoogstrate, Kaspar Draaisma, Santoesha A Ghisai, Levi van Hijfte, Nastaran Barin, Iris de Heer

Cancer Cell· April 2023

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3D-Engineered Scaffolds to Study Microtubes and Localization of Epidermal Growth Factor Receptor in Patient-Derived Glioma Cells.
Nastaran Barin, Hayri E Balcioglu, Iris de Heer, Maurice de Wit, Martine L M Lamfers

Small· December 2022

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Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
C Mircea S Tesileanu, Marc Sanson, Wolfgang Wick, Alba A Brandes, Paul M Clement, Iris de Heer

Clin Cancer Res· June 2022

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Prognostic Significance of DNA Methylation Profiles at MRI Enhancing Tumor Recurrence: a Report from the EORTC 26091 TAVAREC Trial.
Kaspar Draaisma, C Mircea S Tesileanu, Iris de Heer, Martin Klein, Marion Smits

Clin Cancer Res· June 2022

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The EGFRvIII transcriptome in glioblastoma: A meta-omics analysis.
Youri Hoogstrate, Santoesha A Ghisai, Maurice de Wit, Iris de Heer, Kaspar Draaisma

Neuro Oncol· March 2022

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Midlatency auditory evoked potentials during anesthesia in children: A narrative review.
Yuen M Cheung, Iris J de Heer, Robert Jan Stolker, Frank Weber

Paediatr Anaesth· October 2021

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Prognostic significance of genome-wide DNA methylation profiles within the randomized, phase 3, EORTC CATNON trial on non-1p/19q deleted anaplastic glioma.
C Mircea S Tesileanu, Martin J van den Bent, Marc Sanson, Wolfgang Wick, Alba A Brandes, Iris de Heer

Neuro Oncol· September 2021

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Non-IDH1-R132H IDH1/2 mutations are associated with increased DNA methylation and improved survival in astrocytomas, compared to IDH1-R132H mutations.
C Mircea S Tesileanu, Wies R Vallentgoed, Marc Sanson, Walter Taal, Paul M Clement, Iris de Heer

Acta Neuropathol· June 2021

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Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study.
Martin J van den Bent, C Mircea S Tesileanu, Wolfgang Wick, Marc Sanson, Alba Ariela Brandes, Iris de Heer

Lancet Oncol· June 2021

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The predictive value of the Pleth Variability Index on fluid responsiveness in spontaneously breathing anaesthetized children-A prospective observational study.
Frank Weber, Bharat K Rashmi, Gülhan Karaoz-Bulut, Jaap Dogger, Iris J de Heer

Paediatr Anaesth· October 2020

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Electroencephalographic density spectral array monitoring during propofol sedation in teenagers, using the narcotrend electroencephalographic monitor.
Iris J de Heer, Annejet T Warmenhoven, Frank Weber

Minerva Anestesiol· June 2020

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Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors.
Maurice de Wit, Ya Gao, Darlene Mercieca, Iris de Heer, Bart Valkenburg

EBioMedicine· June 2020

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EGFR mutations are associated with response to depatux-m in combination with temozolomide and result in a receptor that is hypersensitive to ligand.
Youri Hoogstrate, Wies Vallentgoed, Johan M Kros, Iris de Heer, Maurice de Wit

Neurooncol Adv· December 2019

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Defining EGFR amplification status for clinical trial inclusion.
Pim J French, Marica Eoli, Juan Manuel Sepulveda, Iris de Heer, Johan M Kros

Neuro Oncol· October 2019

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Development of a whole plant bioassay to test effects of potentized calcium carbonate in pillule formulation.
Bianka Lutz, Iris Heer, Ramona Katzensteiner, Christa Raak, Ursula Wolf

Complement Ther Med· October 2018

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Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.
Martin J van den Bent, Martin Klein, Marion Smits, Jaap C Reijneveld, Pim J French, Iris de Heer

Lancet Oncol· September 2018

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